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Results for “First Line Therapy”

4,208 trials

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Showing 20 of 4,208 results

Not applicableUnknownNCT06349044
What this trial is testing

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Who this might be right for
Her-2 Negative Adenocarcinoma of the Gastro-oesophageal Junction/Gastric AdenocarcinomaHepatocellular CarcinomaBiliary Tract Carcinoma+1 more
Zhejiang Cancer Hospital 120
Post-approval studies (Phase 4)Study completedNCT01129336
What this trial is testing

Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients

Who this might be right for
First or Second Line HER2-negative Breast CancerMetastatic Disease Without Bone Metastasis
Novartis Pharmaceuticals 44
Testing effectiveness (Phase 2)Looking for participantsNCT06971211
What this trial is testing

Radiotherapy Combined With Fluzopanib and Abiraterone Acetate Tablets (II) Treatment for mCRPC

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
Jianbin Bi 40
Testing effectiveness (Phase 2)Looking for participantsNCT07032792
What this trial is testing

Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

Who this might be right for
Cardiac DiseaseSurgeryBleeding
Northwell Health 140
Testing effectiveness (Phase 2)UnknownNCT05055167
What this trial is testing

Envafolimab as First-line Treatment of Aged Patients in Advanced NSCLC

Who this might be right for
Non-small Cell Lung Cancer Stage IV
The First Affiliated Hospital of Xiamen University 20
Testing effectiveness (Phase 2)Study completedNCT03562871
What this trial is testing

IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC

Who this might be right for
NSCLC
IO Biotech 109
Testing effectiveness (Phase 2)Study completedNCT01160744
What this trial is testing

Pemetrexed and Carboplatin/Cisplatin or Gemcitabine and Carboplatin/Cisplatin With or Without IMC-1121B in Participants Previously Untreated With Recurrent or Advanced Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Eli Lilly and Company 280
Testing effectiveness (Phase 2)Ended earlyNCT00531115
What this trial is testing

Phase II Study to Evaluate Safety and Efficacy of Cetuximab in Combination With XELOX for 12 Weeks Followed by Maintenance Treatment With Cetuximab Plus Capecitabine as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer.

Who this might be right for
Metastatic Colorectal Cancer
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 28
Early research (Phase 1)Study completedNCT01346540
What this trial is testing

A Phase I/II Study of Continuous Oral Treatment With BIBF 1120 Added to Standard Gemcitabine/Cisplatin Therapy in First Line NSCLC Patients With Squamous Cell Histology.

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 16
Large-scale testing (Phase 3)UnknownNCT03794440
What this trial is testing

Evaluate the Efficacy and Safety of Sintilimab in Combination With IBI305 (Anti-VEGF Monoclonal Antibody) Compared to Sorafenib as the First-Line Treatment for Advanced Hepatocellular Carcinoma.

Who this might be right for
Hepatocellular Carcinoma
Innovent Biologics (Suzhou) Co. Ltd. 595
Testing effectiveness (Phase 2)Study completedNCT01844791
What this trial is testing

An Exploratory Study of OCZ103-OS in Combination With Standard of Care in Stage IV Non-Small Cell Lung Cancer (NSCLC) Patients

Who this might be right for
Non-small Cell Lung Cancer
Oncozyme Pharma Inc. 25
Testing effectiveness (Phase 2)Study completedNCT01258608
What this trial is testing

Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Human Genome Sciences Inc., a GSK Company 101
Large-scale testing (Phase 3)Study completedNCT03923725
What this trial is testing

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs.

Who this might be right for
Plasmodium Falciparum Malaria (Uncomplicated)
University of Oxford 2,583
Testing effectiveness (Phase 2)Ended earlyNCT00138125
What this trial is testing

Fulvestrant and/or Trastuzumab as First-Line Therapy in Treating Postmenopausal Women With Stage IV Breast Cancer

Who this might be right for
Breast Cancer
Translational Oncology Research International 2
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06094868
What this trial is testing

Clinical Study of Fruquintinib Combined With Sintilimab and XELOX Regimen in the Treatment of Advanced Cancer

Who this might be right for
Gastric Cancer
Second Affiliated Hospital of Nanchang University 45
Not applicableStudy completedNCT01832415
What this trial is testing

First Line Ovarian Cancer Treatment - Cohort Study

Who this might be right for
Epithelial Ovarian Cancer
ARCAGY/ GINECO GROUP 500
Large-scale testing (Phase 3)Study completedNCT03779074
What this trial is testing

Comparing the Efficacy of Hybrid, High-dose Dual and Bismuth Quadruple Therapies

Who this might be right for
Helicobacter Pylori Infection
Kaohsiung Veterans General Hospital. 918
Early research (Phase 1)Active Not RecruitingNCT06049576
What this trial is testing

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

Who this might be right for
Clear Cell Renal Cell CarcinomaSarcomatoid Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8+1 more
City of Hope Medical Center 31
Large-scale testing (Phase 3)Study completedNCT00384176
What this trial is testing

First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX

Who this might be right for
Colorectal Cancer
AstraZeneca 1,814
Testing effectiveness (Phase 2)Study completedNCT01605890
What this trial is testing

Trial Evaluating a First Line Combination Therapy With Raltegravir, Emtricitabine and Tenofovir in HIV-2 Infected Patients

Who this might be right for
HIV-2 Infection
ANRS, Emerging Infectious Diseases 30
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