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Results for “First in Man Study to Evaluate Initial Safety”

731 trials

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Showing 20 of 731 results

Testing effectiveness (Phase 2)Ended earlyNCT05348889
What this trial is testing

First-in-Human (FIH) Trial of 1A46 in Subjects with Advanced CD20 And/or CD19 Positive B-cell Hematologic Malignancies

Who this might be right for
Non-Hodgkin's Lymphoma (disorder)Acute Lymphoid Leukemia, Disease (disorder)
Chimagen Biosciences, Ltd 7
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06895889
What this trial is testing

EB-OC for the Treatment of Focal Chondral/Osteochondral Defects in the Knee

Who this might be right for
Chondral DefectOsteochondral Defect
Epibone, Inc. 36
Early research (Phase 1)Study completedNCT05307406
What this trial is testing

A First-in-Human Study With XAB05 in Healthy Subjects

Who this might be right for
Infection, Bacterial
Xenothera SAS 25
Early research (Phase 1)Looking for participantsNCT06911008
What this trial is testing

MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers

Who this might be right for
Metastatic Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
Mayo Clinic 42
Early research (Phase 1)Study completedNCT03599063
What this trial is testing

Singe Dose, First in Human Study of PF- 06946860 in Healthy Adult Subjects

Who this might be right for
Healthy
Pfizer 63
Early research (Phase 1)Looking for participantsNCT06577337
What this trial is testing

Phase 1 Single Ascending Doses (SAD) of M5542 in Healthy Participants

Who this might be right for
Healthy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 49
Early research (Phase 1)Ended earlyNCT04601285
What this trial is testing

A Phase I Study of JS108 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Shanghai Junshi Bioscience Co., Ltd. 25
Early research (Phase 1)Study completedNCT04405908
What this trial is testing

SCB-2019 as COVID-19 Vaccine

Who this might be right for
COVID-19
Clover Biopharmaceuticals AUS Pty 166
Early research (Phase 1)Ended earlyNCT02041715
What this trial is testing

Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study for Intravenous (IV) TKM-100802

Who this might be right for
Ebola Virus Infection
Arbutus Biopharma Corporation 21
Not applicableLooking for participantsNCT06552689
What this trial is testing

Sutra Hemi-valve First-in-Human Study

Who this might be right for
Mitral Regurgitation
Sutra Medical, Inc. 15
Early research (Phase 1)Study completedNCT04144842
What this trial is testing

Phase 1 Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of ATOR-1017

Who this might be right for
Solid TumorNeoplasms
Alligator Bioscience AB 27
Early research (Phase 1)Study completedNCT04536337
What this trial is testing

ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects

Who this might be right for
Chronic Hepatitis B
Aligos Therapeutics 165
Early research (Phase 1)UnknownNCT03784131
What this trial is testing

Tissue Engineered Veins in Patients With Chronic Venous Insufficiency

Who this might be right for
Chronic Venous Insufficiency
Verigraft AB 15
Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Early research (Phase 1)Looking for participantsNCT06217822
What this trial is testing

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Who this might be right for
Advanced Metastatic Castration-resistant Prostate CancerProstate Specific Membrane Antigen (PSMA) Expression
Bayer 198
Early research (Phase 1)Study completedNCT06536101
What this trial is testing

The Purpose of the Study is to Evaluate the Safety, Tolerability and Pharmacokinetics of Single-ascending and Multiple-ascending Doses of GIM-407

Who this might be right for
Healthy Volunteers
Georgiamune Inc 48
Early research (Phase 1)Ended earlyNCT05561530
What this trial is testing

ALG-125755 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single Doses in Healthy Volunteers, and Single and Multiple Doses in CHB Subjects

Who this might be right for
Chronic Hepatitis B
Aligos Therapeutics 57
Not applicableStudy completedNCT02365454
What this trial is testing

NEXUS™ Aortic Arch Stent Graft System First In Man Study

Who this might be right for
Thoracic Aortic Arch DiseaseThoracic Aortic Aneurysm
Endospan Ltd. 18
Early research (Phase 1)Study completedNCT04644003
What this trial is testing

Safety, Tolerability and Pharmacokinetics Study of STP1 in a Subgroup of Patients With Autism Spectrum Disorder (ASD)

Who this might be right for
Autism Spectrum Disorder
Stalicla SA 12
Testing effectiveness (Phase 2)Looking for participantsNCT06907875
What this trial is testing

A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy

Who this might be right for
Facioscapulohumeral Muscular Dystrophy
Epicrispr Biotechnologies, Inc. 12
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