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Results for “First in Man Study to Evaluate Initial Safety”

754 trials

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Showing 20 of 754 results

Early research (Phase 1)Study completedNCT02316756
What this trial is testing

A Single Ascending Dose Study To Evaluate Safety And Pharmacokinetics Of Compound PF-06648671 In Healthy Subjects

Who this might be right for
Healthy Subjects
Pfizer 18
Early research (Phase 1)Study completedNCT02340572
What this trial is testing

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRS-080

Who this might be right for
Healthy
Pieris Pharmaceuticals GmbH 48
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07460375
What this trial is testing

Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
LigaChem Biosciences, Inc. 191
Early research (Phase 1)Study completedNCT03061981
What this trial is testing

Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects

Who this might be right for
Diabetes Mellitus, Type 2
Dong-A ST Co., Ltd. 60
Early research (Phase 1)Study completedNCT03919409
What this trial is testing

First-in-Human Study With Single and Multiple Doses of TS-161 in Healthy Participants

Who this might be right for
Healthy Volunteers
Taisho Pharmaceutical R&D Inc. 70
Early research (Phase 1)Temporarily pausedNCT05993611
What this trial is testing

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Chronic Graft Versus Host DiseaseHematologic and Lymphocytic DisorderSteroid Refractory Graft Versus Host Disease
City of Hope Medical Center 27
Early research (Phase 1)UnknownNCT05921006
What this trial is testing

Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects

Who this might be right for
Drug Safety
Nanjing Ruijie Pharma Co., Ltd. 98
Early research (Phase 1)Study completedNCT05585034
What this trial is testing

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMelanoma Excluding Uveal MelanomaNon-small Cell Lung Cancer, Squamous or Non-squamous+6 more
Xencor, Inc. 60
Early research (Phase 1)Study completedNCT06857799
What this trial is testing

A Study on the Safety, Tolerability and Pharmacokinetics of WS-0101 Tablets in Chinese Healthy Subjects

Who this might be right for
Healthy Adult Subjects
Peking University First Hospital 27
Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Testing effectiveness (Phase 2)Ended earlyNCT05397171
What this trial is testing

A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours

Who this might be right for
Urinary Bladder NeoplasmsColorectal CancerCarcinoma, Non-Small-Cell Lung
AstraZeneca 17
Early research (Phase 1)Study completedNCT03055000
What this trial is testing

Safety and Immunogenicity of a First-in-Human Mosquito Saliva Peptide Vaccine

Who this might be right for
Mosquito-Borne Disease
National Institute of Allergy and Infectious Diseases (NIAID) 49
Testing effectiveness (Phase 2)Study completedNCT02100839
What this trial is testing

Safety Study of AEM-28 to Treat Refractory Hypercholesterolemia

Who this might be right for
HypercholesterolemiaHyperlipoproteinemia Type II
LipimetiX Development, LLC 52
Early research (Phase 1)Ended earlyNCT03426995
What this trial is testing

First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 48
Early research (Phase 1)Looking for participantsNCT07348211
What this trial is testing

First in Human Study of SIM0610 in Solid Tumors

Who this might be right for
Advanced Solid TumoursNon-Small Cell Lung CancerColorectal Cancer+2 more
Jiangsu Simcere Pharmaceutical Co., Ltd. 260
Early research (Phase 1)Looking for participantsNCT05318534
What this trial is testing

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease

Who this might be right for
First in Man Study to Evaluate Initial Safety
Gliknik Inc. 70
Early research (Phase 1)Study completedNCT01906164
What this trial is testing

Study of Single and Multiple Doses of ALS-008176 in Healthy Volunteers

Who this might be right for
Respiratory Syncytial Virus Infections
Alios Biopharma Inc. 101
Early research (Phase 1)Study completedNCT06536101
What this trial is testing

The Purpose of the Study is to Evaluate the Safety, Tolerability and Pharmacokinetics of Single-ascending and Multiple-ascending Doses of GIM-407

Who this might be right for
Healthy Volunteers
Georgiamune Inc 48
Early research (Phase 1)Study completedNCT03758001
What this trial is testing

First in Human Study of IBI101 in Chinese Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Innovent Biologics (Suzhou) Co. Ltd. 38
Early research (Phase 1)Study completedNCT05635084
What this trial is testing

A First-in-human Study of YN001 in Healthy Volunteers

Who this might be right for
Cardiovascular Diseases
Beijing Inno Medicine Co., Ltd. 64
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