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Results for “First in Man Study to Evaluate Initial Safety”

817 trials

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Showing 20 of 817 results

Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Very early researchLooking for participantsNCT06639191
What this trial is testing

[177Lu]Lu-AKIR001 First-in-human Study

Who this might be right for
Thyroid Gland Anaplastic CarcinomaPoorly Differentiated Thyroid CarcinomaCancer Head and Neck+3 more
Karolinska University Hospital 15
Early research (Phase 1)UnknownNCT02728115
What this trial is testing

Safety Evaluation of Cellavita HD Administered Intravenously in Participants With Huntington's Disease

Who this might be right for
Huntington Disease
Azidus Brasil 6
Testing effectiveness (Phase 2)Looking for participantsNCT07460375
What this trial is testing

Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
LigaChem Biosciences, Inc. 191
Early research (Phase 1)WithdrawnNCT05487495
What this trial is testing

Donor-Derived CD5 CAR T (CT125B) Cells for Relapsed or Refractory T- Cell Acute Lymphoblastic Leukemia/Lymphoma

Who this might be right for
T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Beijing Boren Hospital
Early research (Phase 1)Not Yet RecruitingNCT07568041
What this trial is testing

Phase 1 Study to Evaluate the Safety and Tolerability of 8M2D in Healthy People and Alzheimer's Patients

Who this might be right for
Alzheimer's Disease (AD)
Cenna Biosciences Inc. 54
Early research (Phase 1)Study completedNCT05585034
What this trial is testing

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMelanoma Excluding Uveal MelanomaNon-small Cell Lung Cancer, Squamous or Non-squamous+6 more
Xencor, Inc. 60
Early research (Phase 1)Study completedNCT06762457
What this trial is testing

A First-in-Human Single and Multiple Ascending Dose Study of MT-501

Who this might be right for
Healthy Volunteers
Mirador Therapeutics, Inc. 72
Early research (Phase 1)Study completedNCT04504669
What this trial is testing

First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

Who this might be right for
Clear Cell Renal Cell CancerNon-Small-Cell Lung CancerTriple Negative Breast Neoplasms+6 more
AstraZeneca 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05593094
What this trial is testing

Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsHER2-positive Breast Cancer
Hoffmann-La Roche 210
Early research (Phase 1)Looking for participantsNCT07422207
What this trial is testing

Investigate the Safety, Tolerability, and Pharmacokinetics of ME3241 Administered Intravenously in Healthy Adult Participants

Who this might be right for
Healthy Volunteers
Meiji Pharma USA Inc. 104
Early research (Phase 1)Active Not RecruitingNCT05753501
What this trial is testing

Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies

Who this might be right for
Hematologic Cancer
AbbVie 135
Early research (Phase 1)Study completedNCT01906164
What this trial is testing

Study of Single and Multiple Doses of ALS-008176 in Healthy Volunteers

Who this might be right for
Respiratory Syncytial Virus Infections
Alios Biopharma Inc. 101
Early research (Phase 1)Study completedNCT05723692
What this trial is testing

A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers

Who this might be right for
Healthy Volunteers
AltruBio Inc. 56
Early research (Phase 1)Active Not RecruitingNCT06216093
What this trial is testing

Phase I, First-In Human Study to Evaluate Safety and Tolerability of EuRSV in Healthy Adults Aged Between 19 Years and 80 Years

Who this might be right for
Respiratory Syncytial Virus InfectionsRespiratory Syncytial Virus (RSV)
EuBiologics Co.,Ltd 100
Early research (Phase 1)Study completedNCT06402136
What this trial is testing

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Who this might be right for
Healthy Volunteers Only
Traws Pharma, Inc. 57
Large-scale testing (Phase 3)Study completedNCT05917509
What this trial is testing

Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral Therapy

Who this might be right for
HIV Infections
ViiV Healthcare 171
Early research (Phase 1)Study completedNCT04350736
What this trial is testing

First in Human SAD and MAD Study of Inhaled TD-0903, a Potential Treatment for ALI Associated With COVID-19

Who this might be right for
Acute Lung Injury (ALI) Associated With COVID-19Inflammatory Lung Conditions Associated With COVID-19
Theravance Biopharma 54
Early research (Phase 1)Looking for participantsNCT07670858
What this trial is testing

Study of Intralesional FLD-103 in Subjects With Basal Cell Carcinoma (BCC)

Who this might be right for
Nodular Basal Cell Carcinoma
Feldan Therapeutics 48
Early research (Phase 1)Study completedNCT03403348
What this trial is testing

A First-In-Human Study of Orally Administered JNJ-64417184 to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses, and the Antiviral Activity of Multiple Doses in a Respiratory Syncytial Virus (RSV) Challenge Study in Healthy Participants

Who this might be right for
Healthy
Janssen BioPharma, Inc. 130
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