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Results for “First-line Treatment”

4,311 trials

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Showing 20 of 4,311 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07739186
What this trial is testing

A Study Evaluating BL-B01D1 in Combination With a PD-1/VEGF Bispecific Antibody Versus Tislelizumab Plus Platinum-doublet Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer(PANKU-Lung06)

Who this might be right for
Non-squamous Non-small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 120
Large-scale testing (Phase 3)Looking for participantsNCT07152405
What this trial is testing

BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-positive Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Sichuan Baili Pharmaceutical Co., Ltd. 490
Testing effectiveness (Phase 2)Looking for participantsNCT05190094
What this trial is testing

Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies.

Who this might be right for
Hormonal Receptors Positive, HER2 Negative, Advanced Breast Cancer
International Cancer Research Group, United Arab Emirates 80
Testing effectiveness (Phase 2)Study completedNCT04361331
What this trial is testing

Two-cohort Study of Toripalimab(PD1)+Lenvatnib, or Gemox+Lenvatinib in Advanced Intrahepatic Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma, Intrahepatic
Shanghai Zhongshan Hospital 61
Testing effectiveness (Phase 2)Looking for participantsNCT06029270
What this trial is testing

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Who this might be right for
Metastatic Nasopharyngeal CarcinomaRecurrent Nasopharyngeal CarcinomaStage IV Nasopharyngeal Carcinoma AJCC v8
National Cancer Institute (NCI) 156
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06604351
What this trial is testing

Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction

Who this might be right for
Non-Small Cell Lung Cancer
Hunan Province Tumor Hospital 39
Early research (Phase 1)Looking for participantsNCT07316686
What this trial is testing

Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Castration-Resistant Prostate Adenocarcinoma

Who this might be right for
Prostate Cancer (Adenocarcinoma)
Instituto do Cancer do Estado de São Paulo 18
Testing effectiveness (Phase 2)Ended earlyNCT02452970
What this trial is testing

RRx-001 in Second Line Treatment of Advanced Cholangiocarcinoma Prior to Readministration of First-Line Therapy

Who this might be right for
Cholangiocarcinoma
EpicentRx, Inc. 4
Large-scale testing (Phase 3)Active Not RecruitingNCT05224141
What this trial is testing

Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)

Who this might be right for
Small Cell Lung Carcinoma
Merck Sharp & Dohme LLC 460
Not applicableStudy completedNCT02940639
What this trial is testing

Real-Life Effectiveness and Safety in Participants With Advanced/Metastatic Renal Cell Carcinoma Starting 1st Line Nivolumab and Ipilimumab Combination Therapy or Nivolumab Monotherapy After Prior Therapy

Who this might be right for
Renal Cell Carcinoma
Bristol-Myers Squibb 499
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07420439
What this trial is testing

Treatment in Patients With Advanced Non-Small Cell Lung Carcinoma and Interstitial Lung Disease

Who this might be right for
Non Small Cell Lung Cancer MetastaticInterstitial Lung Disease (ILD)
Intergroupe Francophone de Cancerologie Thoracique 108
Testing effectiveness (Phase 2)UnknownNCT05822453
What this trial is testing

Gemcitabine Plus S1 and Tislelizumab in the First Line Therapy of Advanced Biliary Tract Carcinoma

Who this might be right for
Biliary Tract Carcinoma
Peking Union Medical College Hospital 20
Early research (Phase 1)Ended earlyNCT01714037
What this trial is testing

A Clinical Study on the Safety and Efficacy of Debio 0932 in Combination With Standard of Care in Patients With Non-small Cell Lung Cancer [NSCLC]

Who this might be right for
Non-small Cell Lung Cancer
Debiopharm International SA 82
Testing effectiveness (Phase 2)Study completedNCT00275951
What this trial is testing

Cetuximab Plus P-HDFL for the First-line Treatment of Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
National Taiwan University Hospital 39
Testing effectiveness (Phase 2)Study completedNCT01802684
What this trial is testing

OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer

Who this might be right for
Unresectable Metastatic Colorectal Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 49
Large-scale testing (Phase 3)Not Yet RecruitingNCT07633873
What this trial is testing

SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for Patients With PD-L1-Positive Locally Advanced or Metastatic NSCLC（SYNSTAR 04）

Who this might be right for
Non-Small Cell Lung Cancer
CSPC Megalith Biopharmaceutical Co.,Ltd. 500
Not applicableUnknownNCT03884205
What this trial is testing

GDPE/CEOPE Compared With CEOPE for Newly Diagnosed Patients With PTCL

Who this might be right for
PTCLGemcitabine
Shandong Provincial Hospital 120
Not applicableEnded earlyNCT01098422
What this trial is testing

Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver

Who this might be right for
Colorectal NeoplasmsLiver Neoplasms
Tony Reid, M.D., Ph.D. 10
Testing effectiveness (Phase 2)Study completedNCT01244451
What this trial is testing

GIMEMA CLL0809 Study (BendOfa)

Who this might be right for
Patients With CLL Relapsing After an Initial Response (CR, PR ≥ 6 Months) Following no More Than Two Prior Treatment Lines; orPatients With CLL Refractory (SD, PD or CR/PR < 6 Months) Following no More Than Two Prior Treatment Lines
Gruppo Italiano Malattie EMatologiche dell'Adulto 49
Testing effectiveness (Phase 2)UnknownNCT01131429
What this trial is testing

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Who this might be right for
Neoplasms, LungCarcinoma, Non-Small Cell LungDrug Therapy+1 more
Chinese PLA General Hospital 60
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