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Results for “Folate Receptor Alpha Positive”

24 trials

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Showing 20 of 24 results

Early research (Phase 1)WithdrawnNCT05622591
What this trial is testing

ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AML

Who this might be right for
Acute Myeloid LeukemiaAML, ChildhoodRelapsed Pediatric AML+1 more
Elucida Oncology
Not applicableNot Yet RecruitingNCT07687602
What this trial is testing

Evaluate Adverse Events and Change in Disease Activity of Mirvetuximab Soravtansine-gynx in Adults With Folate Receptor-Alpha Positive, Platinum-Resistant Ovarian Cancer in a Real-World Setting

Who this might be right for
Folate Receptor-Alpha Positive Platinum-Resistant High-Grade Serous Epithelial Ovarian CancerFolate Receptor-Alpha Positive Platinum-Resistant Fallopian Tube CancerFolate Receptor-Alpha Positive Platinum-Resistant Primary Peritoneal Cancer
AbbVie
Early research (Phase 1)Ended earlyNCT02629549
What this trial is testing

Intraoperative Imaging of Pituitary Adenomas by OTL

Who this might be right for
NeoplasmsPituitary Neoplasms
University of Pennsylvania 33
Testing effectiveness (Phase 2)Looking for participantsNCT03832361
What this trial is testing

Evaluation of Mirvetuximab Soravtansine (IMGN853) in Women With Folate Receptor-α Positive Endometrial Cancer

Who this might be right for
Endometrial Cancer
Alessandro Santin 50
Early research (Phase 1)WithdrawnNCT04941378
What this trial is testing

OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer

Who this might be right for
Ovarian Cancer
Abramson Cancer Center at Penn Medicine
Testing effectiveness (Phase 2)Study completedNCT03106077
What this trial is testing

Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast Cancer

Who this might be right for
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8Anatomic Stage IIB Breast Cancer AJCC v8+18 more
M.D. Anderson Cancer Center 96
Early research (Phase 1)Study completedNCT03552471
What this trial is testing

Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationFolate Receptor Alpha Positive+7 more
Ohio State University Comprehensive Cancer Center 25
Testing effectiveness (Phase 2)Looking for participantsNCT04606914
What this trial is testing

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Who this might be right for
Ovarian CancerFallopian TubePrimary Peritoneal Cancer
University of Alabama at Birmingham 70
Testing effectiveness (Phase 2)Study completedNCT01689766
What this trial is testing

Study Using FolateScan to Identify Subjects With Folate Receptor-Positive Metastatic Renal Cell Carcinoma

Who this might be right for
Metastatic Renal Cell Carcinoma
Endocyte 150
Testing effectiveness (Phase 2)Study completedNCT02872701
What this trial is testing

OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules

Who this might be right for
Lung NeoplasmsLung Cancer
On Target Laboratories, LLC 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT06365853
What this trial is testing

Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Who this might be right for
Recurrent Ovarian CancerFolate Receptor-Alpha Positive
AbbVie 108
Testing effectiveness (Phase 2)Study completedNCT02317705
What this trial is testing

Phase 2 Study of OTL38 for Intra-operative Imaging of Folate Receptor-alpha Positive Ovarian Cancer

Who this might be right for
Ovarian Cancer
On Target Laboratories, LLC 48
Large-scale testing (Phase 3)Study completedNCT04241315
What this trial is testing

ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting

Who this might be right for
Lung NeoplasmsLung Cancer
On Target Laboratories, LLC 112
Testing effectiveness (Phase 2)Study completedNCT01577654
What this trial is testing

Phase 2 Study of EC145 Alone Versus EC145+Docetaxel Versus Docetaxel Alone in Participants With FR(++) 2nd Line Non Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Endocyte 203
Large-scale testing (Phase 3)Study completedNCT03180307
What this trial is testing

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

Who this might be right for
Ovarian Cancer
On Target Laboratories, LLC 140
Not applicableUnknownNCT04521491
What this trial is testing

A Trial of Adjuvant Therapy After Hepatocarcinoma Resection Based on Folate Receptor-positive Circulating Tumor Cells

Who this might be right for
Hepatocellular Carcinoma
Eastern Hepatobiliary Surgery Hospital 184
Early research (Phase 1)Study completedNCT01609556
What this trial is testing

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Mirvetuximab Soravtansine in Adults With Ovarian Cancer and Other Folate Receptor 1 (FOLR1)-Positive Solid Tumors

Who this might be right for
Tumors
ImmunoGen, Inc. 206
Not applicableUnknownNCT05633680
What this trial is testing

Circulating Tumor Cells Screen for Breast Cancer

Who this might be right for
Breast NeoplasmNeoplastic Cells, Circulating
Handan First Hospital 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT06390995
What this trial is testing

TAK-853 in Adult Participants With Folate Receptor Alpha-Positive Advanced Ovarian Cancer And Other Solid Tumors

Who this might be right for
Ovarian CancerSolid Tumors
Takeda 28
Testing effectiveness (Phase 2)Study completedNCT02606305
What this trial is testing

Study of Mirvetuximab Soravtansine in Combination With Bevacizumab, Carboplatin, Pegylated Liposomal Doxorubicin, Pembrolizumab, or Bevacizumab + Carboplatin in Participants With Folate Receptor Alpha (FRα) Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Epithelial Ovarian CancerPrimary Peritoneal CancerFallopian Tube Cancer
ImmunoGen, Inc. 264
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