Testing effectiveness (Phase 2)Looking for participantsNCT04901975What this trial is testingFibrosis and the FontanWho this might be right forSingle-ventricle Children's Hospital of Philadelphia 145
Not applicableLooking for participantsNCT07029230What this trial is testingBlood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.Who this might be right forCongenital Heart SurgeryCongenital Heart Disease in ChildrenFontan Physiology Martin Schweiger 225
Not applicableStudy completedNCT02378857What this trial is testingFontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term EffectsWho this might be right forCongenital Heart Disease Oslo University Hospital 76
Large-scale testing (Phase 3)Study completedNCT03013751What this trial is testingA Extension Study of Udenafil in AdolescentsWho this might be right forFunctional Single Ventricle Heart Disease Mezzion Pharma Co. Ltd 301
Large-scale testing (Phase 3)WithdrawnNCT01607983What this trial is testingEffects of Pulmonary Vasodilation Upon VA Coupling in Fontan PatientsWho this might be right forCongenital Heart DiseaseFontan University of California, San Francisco
Testing effectiveness (Phase 2)Ended earlyNCT02004756What this trial is testingMechanisms of Dysfunction and the Influence of Exercise on Cardiac and Musculoskeletal FunctionWho this might be right forCongenital Heart Disease The Hospital for Sick Children 10
Not applicableNot Yet RecruitingNCT07220226What this trial is testingVenous Compression in FontanWho this might be right forSingle-ventricleFontan Circulation University of Texas Southwestern Medical Center 20
Not applicableStudy completedNCT03223168What this trial is testingNoninvasive Negative Pressure Ventilation to Support Failing Fontan PhysiologyWho this might be right forFailing Fontan PhysiologyPediatric Congenital Heart Disease University of Michigan 10
Not applicableStudy completedNCT03339466What this trial is testingInspiratory Muscle Therapy in Subjects With Fontan CirculationsWho this might be right forSingle-ventricle Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 7
Not applicableStudy completedNCT03119090What this trial is testingFontan Imaging Biomarkers (FIB) StudyWho this might be right forSingle-ventricleCongenital Heart Disease Boston Children's Hospital 200
Testing effectiveness (Phase 2)Study completedNCT02201342What this trial is testingPharmacokinetic/Pharmacodynamic Study of Udenafil in AdolescentsWho this might be right forSingle Ventricle Heart Disease After Fontan Surgery Mezzion Pharma Co. Ltd 36
Not applicableUnknownNCT01413308What this trial is testingPulmonary Functions Test in Patients After Fontan OperationWho this might be right forFontan Operation Rambam Health Care Campus 15
Large-scale testing (Phase 3)Study completedNCT02741115What this trial is testingFontan Udenafil Exercise Longitudinal Assessment TrialWho this might be right forSingle Ventricle Heart Disease Mezzion Pharma Co. Ltd 400
Very early researchStudy completedNCT04463394What this trial is testingThe Hemodynamic Effects of Vasopressin in Patients With Fontan PhysiologyWho this might be right forHypotensionFontan Physiology Stanford University 28
Not applicableUnknownNCT05683067What this trial is testingMicrocirculation and Vascular Function After Fontan SurgeryWho this might be right forCongenital Heart Disease University of Leicester 75
Testing effectiveness (Phase 2)Study completedNCT01292551What this trial is testingStudy of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology.Who this might be right forHypoplastic Left Heart SyndromeTricuspid AtresiaOther Specified Congenital Anomalies of Heart Rigshospitalet, Denmark 75
Early research (Phase 1)Study completedNCT03251742What this trial is testingFeasibility and Efficacy of Portable Non-invasive Negative Pressure Ventilation in Fontan PatientsWho this might be right forFontan Physiology University Health Network, Toronto 20
Not applicableStudy completedNCT00974025What this trial is testingImpact of Vitamin C on Endothelial Function and Exercise Capacity in Fontan-Palliated PatientsWho this might be right forFontan ProcedureHypoplastic Left Heart SyndromeTricuspid Atresia University of Michigan 53
Not applicableStudy completedNCT02283255What this trial is testingCardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise TrainingWho this might be right forCongenital Heart DiseaseSingle VentricleUniventricular Heart University of Sao Paulo 60
Large-scale testing (Phase 3)Study completedNCT00480740What this trial is testingThe Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart DiseaseWho this might be right forCardiac TransplantPatent Ductus ArteriousAtrial Septal Defect+1 more Children's National Research Institute 41