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Results for “GATA2 Deficiency”

23 trials

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Showing 20 of 23 results

Early research (Phase 1)Temporarily pausedNCT06454409
What this trial is testing

Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Myelodysplastic Syndrome/Acute Myeloid LeukemiaRecurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic Syndrome+2 more
City of Hope Medical Center 20
Not applicableLooking for participantsNCT01905826
What this trial is testing

Natural History Study of GATA2 Deficiency and Related Disorders

Who this might be right for
GATA2 Deficiency
National Institute of Allergy and Infectious Diseases (NIAID) 600
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04844177
What this trial is testing

Total Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia

Who this might be right for
Severe Congenital NeutropeniaGATA2 Deficiency
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 10
Early research (Phase 1)Looking for participantsNCT06357182
What this trial is testing

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome/Acute Myeloid Leukemia
OHSU Knight Cancer Institute 24
Early research (Phase 1)UnknownNCT04743115
What this trial is testing

A Phase I, Open-Label, Dose Escalation and Cohort Expansion Study of BS HH 002.SA in Patients With AML and MDS

Who this might be right for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Shanghai Bensen Pharmaceutical Co., Ltd. 66
Early research (Phase 1)UnknownNCT05703204
What this trial is testing

QLF32101 in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia and Myelodysplastic Syndrome
Qilu Pharmaceutical Co., Ltd. 122
Not applicableLooking for participantsNCT01212055
What this trial is testing

Apheresis of Patients With Immunodeficiency

Who this might be right for
LAD-1DOCK8GATA2 Deficancy
National Cancer Institute (NCI) 7
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Testing effectiveness (Phase 2)UnknownNCT03018405
What this trial is testing

A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications

Who this might be right for
Acute Myeloid Leukemia/Myelodysplastic SyndromeMultiple Myeloma (MM)
Celyad Oncology SA 146
Testing effectiveness (Phase 2)Active Not RecruitingNCT01522976
What this trial is testing

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic LeukemiaChronic Myelomonocytic Leukemia-1Chronic Myelomonocytic Leukemia-2+4 more
National Cancer Institute (NCI) 282
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Testing effectiveness (Phase 2)Study completedNCT00923364
What this trial is testing

Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC

Who this might be right for
MDSImmunodeficiencyGATA2
National Cancer Institute (NCI) 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT05907746
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency

Who this might be right for
GATA2Immunodeficiency
National Cancer Institute (NCI) 7
Testing effectiveness (Phase 2)Looking for participantsNCT01861106
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

Who this might be right for
GATA2ImmunodeficiencyMDS
National Cancer Institute (NCI) 144
Large-scale testing (Phase 3)Study completedNCT03092674
What this trial is testing

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia
National Cancer Institute (NCI) 76
Early research (Phase 1)WithdrawnNCT04361058
What this trial is testing

Nivolumab for High-Risk MDS/AML Patients After Allogeneic Stem Cell Transplant With Post-Transplant Cyclophosphamide

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic SyndromesMyelodysplastic Syndrome Acute Myeloid Leukemia
SCRI Development Innovations, LLC
Early research (Phase 1)Ended earlyNCT02846376
What this trial is testing

Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant

Who this might be right for
Acute Myeloid Leukemia and Myelodysplastic Syndrome
Hackensack Meridian Health 8
Early research (Phase 1)Looking for participantsNCT06372717
What this trial is testing

Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

Who this might be right for
Acute Myeloid Leukemia RefractoryMyelodysplastic Syndrome Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts+2 more
Apollo Therapeutics Ltd 100
Not applicableLooking for participantsNCT00001467
What this trial is testing

Genetic Analysis of Immune Disorders

Who this might be right for
DOK 8STAT1GATA2+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 5,000
Early research (Phase 1)Looking for participantsNCT06484062
What this trial is testing

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia+6 more
National Cancer Institute (NCI) 54
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