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Results for “GBA Gene Mutation”

20 trials

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Showing 20 of 20 results

Testing effectiveness (Phase 2)Study completedNCT05287503
What this trial is testing

Ambroxol as a Disease-modifying Treatment in GBA-PD

Who this might be right for
Parkinson DiseaseGBA Gene Mutation
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 65
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055087
What this trial is testing

Prevent Cognitive Decline in GBA-associated Parkinson's Disease

Who this might be right for
Parkinson's Disease
University Hospital Tuebingen 120
Testing effectiveness (Phase 2)Ended earlyNCT02906020
What this trial is testing

A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation

Who this might be right for
Parkinson's Disease
Genzyme, a Sanofi Company 273
Testing effectiveness (Phase 2)Active Not RecruitingNCT04411654
What this trial is testing

Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

Who this might be right for
Gaucher Disease, Type 2
Prevail Therapeutics 7
Testing effectiveness (Phase 2)WithdrawnNCT07011771
What this trial is testing

A Clinical Trial of CAP-003 Gene Therapy in Adult Patients With GBA1 Associated Parkinson's Disease

Who this might be right for
GBA1 Parkinson Disease
Capsida Biotherapeutics, Inc.
Not applicableLooking for participantsNCT04388969
What this trial is testing

World Data on Ambroxol for Patients With GD and GBA Related PD

Who this might be right for
Gaucher DiseaseParkinson DiseaseGBA Gene Mutation
Shaare Zedek Medical Center 300
Not applicableStudy completedNCT04101968
What this trial is testing

The GBA Multimodal Study in Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationGaucher Disease
Pacific Parkinson's Research Centre 30
Not applicableStudy completedNCT04268030
What this trial is testing

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

Who this might be right for
Parkinson Disease
Rush University Medical Center 9
Not applicableUnknownNCT03811496
What this trial is testing

Biomarker Analysis for GBA Associated Parkinson's Disease

Who this might be right for
Parkinson DiseaseGaucher Disease
Lysosomal and Rare Disorders Research and Treatment Center, Inc. 100
Not applicableLooking for participantsNCT06323278
What this trial is testing

Effectiveness of Cognitive Stimulation Treatment in Patients With Parkinson's Disease

Who this might be right for
Parkinson Disease
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 68
Not applicableUnknownNCT05536388
What this trial is testing

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Who this might be right for
Parkinson DiseaseGaucher DiseaseHealthy+1 more
New York Stem Cell Foundation Research Institute 60
Early research (Phase 1)WithdrawnNCT02758730
What this trial is testing

Study Assessing Tolerability and Safety and Exploring the Immunogenicity and Therapeutic Activity of AFFITOPE® PD01A in PD-GBA Patients

Who this might be right for
Parkinson's Disease
Affiris AG
Not applicableLooking for participantsNCT06814431
What this trial is testing

Study on the Incidence of Malignant Neoplasms in Patients With Parkinson's Disease and Heterozygous Mutation of the GBA Gene

Who this might be right for
Idiopathic Parkinson's Disease (PD)
Azienda USL Reggio Emilia - IRCCS 3,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT04127578
What this trial is testing

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

Who this might be right for
Parkinson Disease
Prevail Therapeutics 32
Testing effectiveness (Phase 2)UnknownNCT06193421
What this trial is testing

High-Dose Ambroxol in GBA1-Related Parkinson

Who this might be right for
Parkinson DiseaseGBA Gene Mutation
Agyany Pharma LTD 40
Not applicableStudy completedNCT04668898
What this trial is testing

LRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's Disease

Who this might be right for
Parkinson DiseaseLRRK2GBA Gene Mutation
Icahn School of Medicine at Mount Sinai 203
Not applicableUnknownNCT06451419
What this trial is testing

Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease

Who this might be right for
Parkinson Disease
Juan Pablo Romero. MD, PhD 40
Not applicableUnknownNCT04387812
What this trial is testing

Evaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationLeucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation
Tel-Aviv Sourasky Medical Center 240
Not applicableStudy completedNCT03234478
What this trial is testing

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Who this might be right for
ParkinsonParkinson DiseaseGenetic Predisposition+2 more
Rutgers, The State University of New Jersey 150
Large-scale testing (Phase 3)UnknownNCT05830396
What this trial is testing

GRoningen Early-PD Ambroxol Treatment

Who this might be right for
ParkinsonParkinson Disease
University Medical Center Groningen 80
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