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Results for “GBA1 Parkinson Disease”

32 trials

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Showing 20 of 32 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055087
What this trial is testing

Prevent Cognitive Decline in GBA-associated Parkinson's Disease

Who this might be right for
Parkinson's Disease
University Hospital Tuebingen 120
Very early researchNot Yet RecruitingNCT07685444
What this trial is testing

A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of Intracerebral Injection of LY-N001 Injection for the Treatment of Moderate to Advanced Parkinson's Disease With GBA1 Mutations

Who this might be right for
Parkinson's Disease (PD)
Lingyi Biotech Co., Ltd. 18
Not applicableNot Yet RecruitingNCT07474779
What this trial is testing

Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging

Who this might be right for
Parkinson's Disease (PD)GBA1 Parkinson DiseaseREM Sleep Behavior Disorder (iRBD)
University of Pavia 160
Early research (Phase 1)Looking for participantsNCT06732180
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Parkinson's Disease

Who this might be right for
Parkinson Disease
Gain Therapeutics, Inc. 20
Not applicableStudy completedNCT04268030
What this trial is testing

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

Who this might be right for
Parkinson Disease
Rush University Medical Center 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07414290
What this trial is testing

A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R08b in Parkinson's Disease Patients With GBA1 Mutations

Who this might be right for
Parkinson Disease (PD)
Shanghai Vitalgen BioPharma Co., Ltd. 17
Not applicableUnknownNCT05536388
What this trial is testing

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Who this might be right for
Parkinson DiseaseGaucher DiseaseHealthy+1 more
New York Stem Cell Foundation Research Institute 60
Not applicableEnrolling By InvitationNCT00001215
What this trial is testing

Genetic Studies of Lysosomal Storage Disorders

Who this might be right for
Lysosomal Storage DisordersGaucher DiseaseParkinson Disease
National Human Genome Research Institute (NHGRI) 1,000
Not applicableStudy completedNCT00302146
What this trial is testing

Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations

Who this might be right for
Parkinson DiseaseGaucher Disease
National Human Genome Research Institute (NHGRI) 64
Not applicableStudy completedNCT04668898
What this trial is testing

LRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's Disease

Who this might be right for
Parkinson DiseaseLRRK2GBA Gene Mutation
Icahn School of Medicine at Mount Sinai 203
Testing effectiveness (Phase 2)Study completedNCT05287503
What this trial is testing

Ambroxol as a Disease-modifying Treatment in GBA-PD

Who this might be right for
Parkinson DiseaseGBA Gene Mutation
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 65
Testing effectiveness (Phase 2)UnknownNCT06193421
What this trial is testing

High-Dose Ambroxol in GBA1-Related Parkinson

Who this might be right for
Parkinson DiseaseGBA Gene Mutation
Agyany Pharma LTD 40
Testing effectiveness (Phase 2)Ended earlyNCT02906020
What this trial is testing

A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation

Who this might be right for
Parkinson's Disease
Genzyme, a Sanofi Company 273
Not applicableLooking for participantsNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
Not applicableNo Longer AvailableNCT07522606
What this trial is testing

Compassionate Use for BIA 28-6156 in Patients With Parkinson's Disease (PD) Who Have a Pathogenic Variant in the GBA1 Gene (GBA-PD) and Completed the ACTIVATE Study

Who this might be right for
Parkinson Disease
Bial R&D Investments, S.A.
Not applicableActive Not RecruitingNCT04228172
What this trial is testing

Genotypic Influences on Network Progression in Parkinson's Disease

Who this might be right for
Parkinson's Disease
Northwell Health 32
Not applicableStudy completedNCT03234478
What this trial is testing

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Who this might be right for
ParkinsonParkinson DiseaseGenetic Predisposition+2 more
Rutgers, The State University of New Jersey 150
Not applicableStudy completedNCT04370665
What this trial is testing

Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease

Who this might be right for
Parkinson Disease
InSightec 4
Not applicableUnknownNCT06451419
What this trial is testing

Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease

Who this might be right for
Parkinson Disease
Juan Pablo Romero. MD, PhD 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05819359
What this trial is testing

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Who this might be right for
Parkinson's Disease
Bial R&D Investments, S.A. 237
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