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Results for “GBA1 Parkinson Disease”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)UnknownNCT02914366
What this trial is testing

Ambroxol as a Treatment for Parkinson's Disease Dementia

Who this might be right for
Parkinson's Disease Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 55
Not applicableStudy completedNCT04370665
What this trial is testing

Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease

Who this might be right for
Parkinson Disease
InSightec 4
Testing effectiveness (Phase 2)UnknownNCT06193421
What this trial is testing

High-Dose Ambroxol in GBA1-Related Parkinson

Who this might be right for
Parkinson DiseaseGBA Gene Mutation
Agyany Pharma LTD 40
Not applicableAvailableNCT07522606
What this trial is testing

Compassionate Use for BIA 28-6156 in Patients With Parkinson's Disease (PD) Who Have a Pathogenic Variant in the GBA1 Gene (GBA-PD) and Completed the ACTIVATE Study

Who this might be right for
Parkinson Disease
Bial R&D Investments, S.A.
Not applicableLooking for participantsNCT04388969
What this trial is testing

World Data on Ambroxol for Patients With GD and GBA Related PD

Who this might be right for
Gaucher DiseaseParkinson DiseaseGBA Gene Mutation
Shaare Zedek Medical Center 300
Not applicableLooking for participantsNCT05536388
What this trial is testing

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Who this might be right for
Parkinson DiseaseGaucher DiseaseHealthy+1 more
New York Stem Cell Foundation Research Institute 60
Testing effectiveness (Phase 2)Temporarily pausedNCT07011771
What this trial is testing

A Clinical Trial of CAP-003 Gene Therapy in Adult Patients With GBA1 Associated Parkinson's Disease

Who this might be right for
GBA1 Parkinson Disease
Capsida Biotherapeutics, Inc. 31
Not applicableStudy completedNCT04268030
What this trial is testing

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

Who this might be right for
Parkinson Disease
Rush University Medical Center 9
Large-scale testing (Phase 3)UnknownNCT05830396
What this trial is testing

GRoningen Early-PD Ambroxol Treatment

Who this might be right for
ParkinsonParkinson Disease
University Medical Center Groningen 80
Not applicableUnknownNCT04387812
What this trial is testing

Evaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationLeucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation
Tel-Aviv Sourasky Medical Center 240
Not applicableEnrolling By InvitationNCT06451419
What this trial is testing

Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease

Who this might be right for
Parkinson Disease
Juan Pablo Romero. MD, PhD 40
Not applicableEnrolling By InvitationNCT00001215
What this trial is testing

Genetic Studies of Lysosomal Storage Disorders

Who this might be right for
Lysosomal Storage DisordersGaucher DiseaseParkinson Disease
National Human Genome Research Institute (NHGRI) 1,000
Not applicableStudy completedNCT03234478
What this trial is testing

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Who this might be right for
ParkinsonParkinson DiseaseGenetic Predisposition+2 more
Rutgers, The State University of New Jersey 150
Not applicableLooking for participantsNCT06814431
What this trial is testing

Study on the Incidence of Malignant Neoplasms in Patients with Parkinson's Disease and Heterozygous Mutation of the GBA Gene

Who this might be right for
Idiopathic Parkinson's Disease (PD)
Azienda USL Reggio Emilia - IRCCS 3,000
Not applicableStudy completedNCT04668898
What this trial is testing

LRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's Disease

Who this might be right for
Parkinson DiseaseLRRK2GBA Gene Mutation
Icahn School of Medicine at Mount Sinai 203
Not applicableNot Yet RecruitingNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
Not applicableLooking for participantsNCT04101968
What this trial is testing

The GBA Multimodal Study in Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationGaucher Disease
Pacific Parkinson's Research Centre 25
Not applicableNot Yet RecruitingNCT07474779
What this trial is testing

Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging

Who this might be right for
Parkinson's Disease (PD)GBA1 Parkinson DiseaseREM Sleep Behavior Disorder (iRBD)
University of Pavia 160
Early research (Phase 1)Looking for participantsNCT06732180
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Parkinson's Disease

Who this might be right for
Parkinson Disease
Gain Therapeutics, Inc. 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT04127578
What this trial is testing

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

Who this might be right for
Parkinson Disease
Prevail Therapeutics 32
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