Not applicableLooking for participantsNCT05565443What this trial is testingMR-guided Focused Ultrasound Plus GCaseWho this might be right forParkinsons Disease InSightec 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT05819359What this trial is testingEfficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PDWho this might be right forParkinson's Disease Bial R&D Investments, S.A. 237
Large-scale testing (Phase 3)UnknownNCT05830396What this trial is testingGRoningen Early-PD Ambroxol TreatmentWho this might be right forParkinsonParkinson Disease University Medical Center Groningen 80
Testing effectiveness (Phase 2)UnknownNCT02914366What this trial is testingAmbroxol as a Treatment for Parkinson's Disease DementiaWho this might be right forParkinson's Disease Dementia London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 55
Not applicableLooking for participantsNCT06814431What this trial is testingStudy on the Incidence of Malignant Neoplasms in Patients With Parkinson's Disease and Heterozygous Mutation of the GBA GeneWho this might be right forIdiopathic Parkinson's Disease (PD) Azienda USL Reggio Emilia - IRCCS 3,000
Very early researchNot Yet RecruitingNCT07685444What this trial is testingA Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of Intracerebral Injection of LY-N001 Injection for the Treatment of Moderate to Advanced Parkinson's Disease With GBA1 MutationsWho this might be right forParkinson's Disease (PD) Lingyi Biotech Co., Ltd. 18
Not applicableLooking for participantsNCT06993142What this trial is testingSlow-SPEED: Slowing Parkinson's Early Through Exercise DosageWho this might be right forParkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more Radboud University Medical Center 600
Not applicableActive Not RecruitingNCT04228172What this trial is testingGenotypic Influences on Network Progression in Parkinson's DiseaseWho this might be right forParkinson's Disease Northwell Health 32
Not applicableStudy completedNCT04668898What this trial is testingLRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's DiseaseWho this might be right forParkinson DiseaseLRRK2GBA Gene Mutation Icahn School of Medicine at Mount Sinai 203
Not applicableLooking for participantsNCT04388969What this trial is testingWorld Data on Ambroxol for Patients With GD and GBA Related PDWho this might be right forGaucher DiseaseParkinson DiseaseGBA Gene Mutation Shaare Zedek Medical Center 300
Not applicableStudy completedNCT04370665What this trial is testingBlood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's DiseaseWho this might be right forParkinson Disease InSightec 4
Not applicableStudy completedNCT00302146What this trial is testingPositron Emission Tomography (PET) Imaging in People With Gaucher MutationsWho this might be right forParkinson DiseaseGaucher Disease National Human Genome Research Institute (NHGRI) 64
Not applicableNo Longer AvailableNCT07522606What this trial is testingCompassionate Use for BIA 28-6156 in Patients With Parkinson's Disease (PD) Who Have a Pathogenic Variant in the GBA1 Gene (GBA-PD) and Completed the ACTIVATE StudyWho this might be right forParkinson Disease Bial R&D Investments, S.A.
Testing effectiveness (Phase 2)Ended earlyNCT02906020What this trial is testingA Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene MutationWho this might be right forParkinson's Disease Genzyme, a Sanofi Company 273
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055087What this trial is testingPrevent Cognitive Decline in GBA-associated Parkinson's DiseaseWho this might be right forParkinson's Disease University Hospital Tuebingen 120
Not applicableUnknownNCT05536388What this trial is testingDrug Discovery for Parkinson's With Mutations in the GBA GeneWho this might be right forParkinson DiseaseGaucher DiseaseHealthy+1 more New York Stem Cell Foundation Research Institute 60
Not applicableLooking for participantsNCT06323278What this trial is testingEffectiveness of Cognitive Stimulation Treatment in Patients With Parkinson's DiseaseWho this might be right forParkinson Disease Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 68
Early research (Phase 1)Looking for participantsNCT06732180What this trial is testingSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Parkinson's DiseaseWho this might be right forParkinson Disease Gain Therapeutics, Inc. 20
Not applicableUnknownNCT04387812What this trial is testingEvaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's DiseaseWho this might be right forParkinson DiseaseGBA Gene MutationLeucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation Tel-Aviv Sourasky Medical Center 240
Not applicableUnknownNCT03811496What this trial is testingBiomarker Analysis for GBA Associated Parkinson's DiseaseWho this might be right forParkinson DiseaseGaucher Disease Lysosomal and Rare Disorders Research and Treatment Center, Inc. 100