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Results for “GBA1 Parkinson Disease”

28 trials

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Showing 20 of 28 results

Not applicableStudy completedNCT03234478
What this trial is testing

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Who this might be right for
ParkinsonParkinson DiseaseGenetic Predisposition+2 more
Rutgers, The State University of New Jersey 150
Not applicableNot Yet RecruitingNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
Testing effectiveness (Phase 2)Active Not RecruitingNCT02914366
What this trial is testing

Ambroxol as a Treatment for Parkinson's Disease Dementia

Who this might be right for
Parkinson's Disease Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 55
Testing effectiveness (Phase 2)Ended earlyNCT02906020
What this trial is testing

A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation

Who this might be right for
Parkinson's Disease
Genzyme, a Sanofi Company 273
Large-scale testing (Phase 3)UnknownNCT05830396
What this trial is testing

GRoningen Early-PD Ambroxol Treatment

Who this might be right for
ParkinsonParkinson Disease
University Medical Center Groningen 80
Not applicableUnknownNCT03811496
What this trial is testing

Biomarker Analysis for GBA Associated Parkinson's Disease

Who this might be right for
Parkinson DiseaseGaucher Disease
Lysosomal and Rare Disorders Research and Treatment Center, Inc. 100
Not applicableLooking for participantsNCT04101968
What this trial is testing

The GBA Multimodal Study in Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationGaucher Disease
Pacific Parkinson's Research Centre 25
Early research (Phase 1)Looking for participantsNCT06732180
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Parkinson's Disease

Who this might be right for
Parkinson Disease
Gain Therapeutics, Inc. 20
Not applicableStudy completedNCT00302146
What this trial is testing

Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations

Who this might be right for
Parkinson DiseaseGaucher Disease
National Human Genome Research Institute (NHGRI) 64
Not applicableEnrolling By InvitationNCT00001215
What this trial is testing

Genetic Studies of Lysosomal Storage Disorders

Who this might be right for
Lysosomal Storage DisordersGaucher DiseaseParkinson Disease
National Human Genome Research Institute (NHGRI) 1,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055087
What this trial is testing

Prevent Cognitive Decline in GBA-associated Parkinson's Disease

Who this might be right for
Parkinson's Disease
University Hospital Tuebingen 120
Testing effectiveness (Phase 2)Looking for participantsNCT04127578
What this trial is testing

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

Who this might be right for
Parkinson Disease
Prevail Therapeutics 32
Not applicableLooking for participantsNCT06323278
What this trial is testing

Effectiveness of Cognitive Stimulation Treatment in Patients With Parkinson's Disease

Who this might be right for
Parkinson Disease
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 68
Not applicableLooking for participantsNCT05536388
What this trial is testing

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Who this might be right for
Parkinson DiseaseGaucher DiseaseHealthy+1 more
New York Stem Cell Foundation Research Institute 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05819359
What this trial is testing

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Who this might be right for
Parkinson's Disease
Bial R&D Investments, S.A. 237
Not applicableLooking for participantsNCT06167603
What this trial is testing

Exploring Brain Molecular Imaging and Blood Biomarkers in Subjects With Glucocerebrosidase Mutations: Toward a Precision Medicine Approach to Characterize Parkinson's Disease Clinical Trajectories

Who this might be right for
Parkinson Disease
IRCCS San Raffaele 140
Not applicableStudy completedNCT04268030
What this trial is testing

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

Who this might be right for
Parkinson Disease
Rush University Medical Center 9
Not applicableEnrolling By InvitationNCT06451419
What this trial is testing

Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease

Who this might be right for
Parkinson Disease
Juan Pablo Romero. MD, PhD 40
Not applicableLooking for participantsNCT05565443
What this trial is testing

MR-guided Focused Ultrasound Plus GCase

Who this might be right for
Parkinsons Disease
InSightec 14
Not applicableUnknownNCT04388969
What this trial is testing

World Data on Ambroxol for Patients With GD and GBA Related PD

Who this might be right for
Gaucher DiseaseParkinson DiseaseGBA Gene Mutation
Shaare Zedek Medical Center 300
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