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Results for “GBA1 Parkinson Disease”

31 trials

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Showing 20 of 31 results

Not applicableNot Yet RecruitingNCT07474779
What this trial is testing

Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging

Who this might be right for
Parkinson's Disease (PD)GBA1 Parkinson DiseaseREM Sleep Behavior Disorder (iRBD)
University of Pavia 160
Not applicableNot Yet RecruitingNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
Testing effectiveness (Phase 2)Ended earlyNCT02906020
What this trial is testing

A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation

Who this might be right for
Parkinson's Disease
Genzyme, a Sanofi Company 273
Early research (Phase 1)Looking for participantsNCT06732180
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Parkinson's Disease

Who this might be right for
Parkinson Disease
Gain Therapeutics, Inc. 20
Testing effectiveness (Phase 2)Study completedNCT05287503
What this trial is testing

Ambroxol as a Disease-modifying Treatment in GBA-PD

Who this might be right for
Parkinson DiseaseGBA Gene Mutation
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 65
Testing effectiveness (Phase 2)UnknownNCT02914366
What this trial is testing

Ambroxol as a Treatment for Parkinson's Disease Dementia

Who this might be right for
Parkinson's Disease Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 55
Large-scale testing (Phase 3)UnknownNCT05830396
What this trial is testing

GRoningen Early-PD Ambroxol Treatment

Who this might be right for
ParkinsonParkinson Disease
University Medical Center Groningen 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT04127578
What this trial is testing

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

Who this might be right for
Parkinson Disease
Prevail Therapeutics 32
Not applicableStudy completedNCT00302146
What this trial is testing

Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations

Who this might be right for
Parkinson DiseaseGaucher Disease
National Human Genome Research Institute (NHGRI) 64
Testing effectiveness (Phase 2)Temporarily pausedNCT07011771
What this trial is testing

A Clinical Trial of CAP-003 Gene Therapy in Adult Patients With GBA1 Associated Parkinson's Disease

Who this might be right for
GBA1 Parkinson Disease
Capsida Biotherapeutics, Inc. 31
Not applicableUnknownNCT04388969
What this trial is testing

World Data on Ambroxol for Patients With GD and GBA Related PD

Who this might be right for
Gaucher DiseaseParkinson DiseaseGBA Gene Mutation
Shaare Zedek Medical Center 300
Not applicableUnknownNCT03811496
What this trial is testing

Biomarker Analysis for GBA Associated Parkinson's Disease

Who this might be right for
Parkinson DiseaseGaucher Disease
Lysosomal and Rare Disorders Research and Treatment Center, Inc. 100
Not applicableEnrolling By InvitationNCT00001215
What this trial is testing

Genetic Studies of Lysosomal Storage Disorders

Who this might be right for
Lysosomal Storage DisordersGaucher DiseaseParkinson Disease
National Human Genome Research Institute (NHGRI) 1,000
Not applicableLooking for participantsNCT06814431
What this trial is testing

Study on the Incidence of Malignant Neoplasms in Patients with Parkinson's Disease and Heterozygous Mutation of the GBA Gene

Who this might be right for
Idiopathic Parkinson's Disease (PD)
Azienda USL Reggio Emilia - IRCCS 3,000
Not applicableLooking for participantsNCT06323278
What this trial is testing

Effectiveness of Cognitive Stimulation Treatment in Patients With Parkinson's Disease

Who this might be right for
Parkinson Disease
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 68
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07414290
What this trial is testing

A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R08b in Parkinson's Disease Patients With GBA1 Mutations

Who this might be right for
Parkinson Disease (PD)
Shanghai Vitalgen BioPharma Co., Ltd. 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07055087
What this trial is testing

Prevent Cognitive Decline in GBA-associated Parkinson's Disease

Who this might be right for
Parkinson's Disease
University Hospital Tuebingen 120
Not applicableUnknownNCT04387812
What this trial is testing

Evaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationLeucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation
Tel-Aviv Sourasky Medical Center 240
Not applicableStudy completedNCT03234478
What this trial is testing

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Who this might be right for
ParkinsonParkinson DiseaseGenetic Predisposition+2 more
Rutgers, The State University of New Jersey 150
Not applicableStudy completedNCT04268030
What this trial is testing

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

Who this might be right for
Parkinson Disease
Rush University Medical Center 9
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