Not applicableUnknownNCT05895942What this trial is testingExploring the Molecular Mechanism Based on KIT MutationWho this might be right forGIST Xijing Hospital 190
Early research (Phase 1)Study completedNCT00654160What this trial is testingIrinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal CancerWho this might be right forAnal CancerCarcinoma of the AppendixColorectal Cancer+9 more Mayo Clinic 7
Not applicableAvailableNCT06948955What this trial is testingExpanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Gastrointestinal Stromal TumorsWho this might be right forGastrointestinal Neoplasms, Gastrointestinal Stromal Tumors Cogent Biosciences, Inc.
Testing effectiveness (Phase 2)Study completedNCT03944304What this trial is testingPaclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib.Who this might be right forGastrointestinal Stromal Tumors Asan Medical Center 40
Testing effectiveness (Phase 2)Study completedNCT02401815What this trial is testingCGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid TumorsWho this might be right forGastrointestinal Stromal Tumors Cogent Biosciences, Inc. 51
Large-scale testing (Phase 3)Study completedNCT02260505What this trial is testingEfficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)Who this might be right forGastrointestinal Stromal TumorsResected Gastrointestinal Stromal TumorsNon-metastatic+2 more Centre Leon Berard 136
Testing effectiveness (Phase 2)Study completedNCT00400569What this trial is testingPhase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue SarcomaWho this might be right forLiposarcomaLeiomyosarcomaFibrosarcoma+1 more H. Lee Moffitt Cancer Center and Research Institute 48
Early research (Phase 1)Study completedNCT04908176What this trial is testingA Drug-drug Interaction Study of Avapritinib and MidazolamWho this might be right forGastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more Blueprint Medicines Corporation 10
Not applicableActive Not RecruitingNCT05038254What this trial is testingEnhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse EventsWho this might be right forClinical Stage IV Esophageal Adenocarcinoma AJCC v8Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+42 more M.D. Anderson Cancer Center 750
Not applicableUnknownNCT03896958What this trial is testingThe PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)Who this might be right forCancer, All TypesCancer of LiverCancer of Stomach+42 more SpeciCare 1,000
Testing effectiveness (Phase 2)Study completedNCT00237185What this trial is testingThe Efficacy and Safety of Imatinib Mesylate in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing C-kit GeneWho this might be right forUnresectable or Metastatic Malignant Gastrointestinal Stromal Tumor (GIST) Novartis Pharmaceuticals 148
Testing effectiveness (Phase 2)Study completedNCT02607332What this trial is testingPaclitaxel in Patients With Metastatic or Advanced Gastrointestinal Stromal Tumors (GIST) After Failure to Imatinib and SunitinibWho this might be right forGastrointestinal Stromal Tumors Asan Medical Center 25
Not applicableActive Not RecruitingNCT04584008What this trial is testingTargeted Agent Evaluation in Digestive Cancers in China Based on Molecular CharacteristicsWho this might be right forBiliary Tract NeoplasmsGastric CancerEsophageal Squamous Cell Carcinoma+6 more Peking University 600
Not applicableStudy completedNCT00976612What this trial is testingNilotinib Pharmacokinetics (PK) in Gastrointestinal Stromal Tumor (GIST): Nilotinib PKWho this might be right forGastrointestinal Stromal Tumors Asan Medical Center 17
Testing effectiveness (Phase 2)Study completedNCT00780494What this trial is testingPh II of Capecitabine, Carboplatin & Bevacizumab for Gastroesophageal Junction & Gastric CarcinomaWho this might be right forStomach CancerGastric (Stomach) CancerNeoplasm of Cardioesophageal Junction+1 more Stanford University 35
Not applicableLooking for participantsNCT07522762What this trial is testingLong-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational StudyWho this might be right forGastrointenstinal Stromal Tumor (GIST) The Netherlands Cancer Institute 330
Early research (Phase 1)Study completedNCT00069940What this trial is testingVaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain TumorWho this might be right forBrain and Central Nervous System TumorsGastrointestinal Stromal TumorSarcoma Dana-Farber Cancer Institute
Not applicableLooking for participantsNCT05464875What this trial is testingStudy of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal TumorsWho this might be right forGastrointestinal Stromal TumorsUnresectable Solid TumorRecurrent Metastatic Malignant Neoplasm Xinhua Zhang, MD 74
Post-approval studies (Phase 4)Ended earlyNCT00461929What this trial is testingChromosome Abnormalities in Chronic Myeloid Leukemia (CML) on Imatinib. GIST Patients on ImatinibWho this might be right forChronic Myeloid LeukemiaGastrointestinal Stromal Cell TumorsChromosome Abnormality University Health Network, Toronto 68
Testing effectiveness (Phase 2)Study completedNCT00474994What this trial is testingSunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent SarcomasWho this might be right forAdult Malignant Fibrous Histiocytoma of BoneDesmoid TumorEndometrial Cancer+3 more Memorial Sloan Kettering Cancer Center 53