Early research (Phase 1)Study completedNCT00472576What this trial is testingAntidepressant Effects of NR2B in Major DepressionWho this might be right forMajor Depression National Institute of Mental Health (NIMH) 5
Early research (Phase 1)Study completedNCT00526968What this trial is testingThe Effects of a Novel NMDA NR2B-Subtype Selective Antagonist, EVT 101, on Brain FunctionWho this might be right forHuman Volunteers Evotec Neurosciences GmbH 19
Not applicableLooking for participantsNCT01238250What this trial is testingOnline Study of People Who Have Genetic Changes and Features of Autism: Simons SearchlightWho this might be right for16P11.2 Deletion Syndrome16p11.2 Duplications1Q21.1 Deletion+181 more Simons Searchlight 100,000
Large-scale testing (Phase 3)Looking for participantsNCT07224581What this trial is testingBeeline: A Phase 3 Study in GRIN-related Neurodevelopmental DisorderWho this might be right forGRIN-related Neurodevelopmental Disorder GRIN Therapeutics, Inc. 100
Early research (Phase 1)Study completedNCT05666687What this trial is testingAn Open-label, Adaptive Design, Positron Emission Tomography Study in Healthy Male Participants to Characterize Receptor Occupancy by MIJ821 in the BrainWho this might be right forMajor Depressive Disorder Novartis Pharmaceuticals 10
Large-scale testing (Phase 3)Looking for participantsNCT07377032What this trial is testingTAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental DisordersWho this might be right forGRIN-related DisordersGRIN1GRIN2A+4 more Meyer Children's Hospital IRCCS 40
Testing effectiveness (Phase 2)Study completedNCT00163085What this trial is testingThe Effects of an NR2B NMDA Antagonist, CP-101,606, in Patients With Parkinson's DiseaseWho this might be right forParkinson's Disease Pfizer 12
Early research (Phase 1)Active Not RecruitingNCT05818943What this trial is testingHoneycomb: Evaluation of Radiprodil in Children with GRIN-related DisorderWho this might be right forGRIN-related Disorders GRIN Therapeutics, Inc. 24