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Results for “Gastroesophageal Junction (GEJ) Cancers”

199 trials

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Showing 20 of 199 results

Early research (Phase 1)Study completedNCT05327231
What this trial is testing

IN10018 Monotherapy or in Combination With Docetaxel in Gastric or GEJ Adenocarcinoma

Who this might be right for
Gastric Cancer
InxMed (Shanghai) Co., Ltd. 33
Testing effectiveness (Phase 2)UnknownNCT04631757
What this trial is testing

Conversion Therapy of Camrelizumab Plus Chemoradiotherapy in Participants With Initial Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Gastric Cancer
Tianjin Medical University Cancer Institute and Hospital 33
Testing effectiveness (Phase 2)Study completedNCT06238752
What this trial is testing

First-line Apatinib Combined With Tislelizumab and Chemotherapy for Advanced GC

Who this might be right for
Advanced Gastric Adenocarcinoma
Renmin Hospital of Wuhan University 33
Not applicableActive Not RecruitingNCT04359732
What this trial is testing

Assessment of Response to nCRT for GEJ Cancer Using a Fully Integrated PET/MRI

Who this might be right for
Esophageal CancerEsophageal Neoplasms
IRCCS San Raffaele 121
Testing effectiveness (Phase 2)Ended earlyNCT04467515
What this trial is testing

Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer

Who this might be right for
Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment
Precirix 13
Testing effectiveness (Phase 2)UnknownNCT05218148
What this trial is testing

SOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positive Locally Advanced Gastric Adenocarcinoma

Who this might be right for
HER2-positiveLocally Advanced Solid TumorImmunotherapy+4 more
Aiping Zhou 44
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Early research (Phase 1)Study completedNCT03538028
What this trial is testing

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Who this might be right for
Cervical CancerMicrosatellite Instability (MSI)-High Endometrial CancerGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+14 more
Incyte Biosciences International Sàrl 22
Testing effectiveness (Phase 2)Study completedNCT02999295
What this trial is testing

Ramucirumab Plus Nivolumab in Participants With Gastric or GEJ Cancer

Who this might be right for
Gastric CancerGastroesophageal Junction Region (GEJ) Cancer
National Cancer Center, Japan 46
Large-scale testing (Phase 3)Looking for participantsNCT06925243
What this trial is testing

Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])Neoadjuvant TherapyAdjuvant Chemotherapy+3 more
Zuoyi Jiao 682
Not applicableNot Yet RecruitingNCT07260461
What this trial is testing

The Efficacy and Safety of Laparoscopic Proximal Gastrectomy With LPG-tbROSF Versus LTG for Localized Proximal Gastric Cancer.

Who this might be right for
Stomach NeoplasmsAdenocarcinoma - Gastroesophageal Junction (GEJ)Gastroesophageal Junction Cancer
First Affiliated Hospital of Wenzhou Medical University 120
Testing effectiveness (Phase 2)Looking for participantsNCT07026149
What this trial is testing

Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer

Who this might be right for
Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
Ruijin Hospital 30
Not applicableActive Not RecruitingNCT06243757
What this trial is testing

Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers

Who this might be right for
Gastric CancerGastroEsophageal CancerGastroesophageal Junction Adenocarcinoma
Memorial Sloan Kettering Cancer Center 4
Testing effectiveness (Phase 2)Study completedNCT04014075
What this trial is testing

DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)

Who this might be right for
Adenocarcinoma Gastric Stage IV With MetastasesAdenocarcinoma - GEJ
Daiichi Sankyo 79
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439110
What this trial is testing

Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 38
Not applicableActive Not RecruitingNCT06504615
What this trial is testing

Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France

Who this might be right for
Gastric AdenocarcinomaGastro-esophageal Junction AdenocarcinomaEsophageal Adenocarcinoma (EAC)+1 more
Bristol-Myers Squibb 208
Testing effectiveness (Phase 2)Active Not RecruitingNCT05128487
What this trial is testing

NDI 1150-101 in Patients With Solid Tumors

Who this might be right for
Solid TumorRenal Cell Carcinoma (Kidney Cancer)Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma+1 more
Nimbus Saturn, Inc. 106
Early research (Phase 1)Ended earlyNCT05980416
What this trial is testing

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

Who this might be right for
Stomach NeoplasmGastrointestinal NeoplasmsDigestive System Neoplasm+2 more
Elevation Oncology 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT03421288
What this trial is testing

Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness

Who this might be right for
Gastric CancerGastroesophageal Junction Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 677
Large-scale testing (Phase 3)Study completedNCT02494583
What this trial is testing

Study of Pembrolizumab (MK-3475) as First-Line Monotherapy and Combination Therapy for Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-062/KEYNOTE-062)

Who this might be right for
Gastric Adenocarcinoma
Merck Sharp & Dohme LLC 763
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