Early research (Phase 1)Study completedNCT03821233What this trial is testingA Dose Finding Study of ZW49 in Patients With HER2-Positive CancersWho this might be right forHER2-expressing Cancers Zymeworks BC Inc. 112
Testing effectiveness (Phase 2)UnknownNCT05594381What this trial is testingA Biomarker Study for Predicting the Efficacy of Neoadjuvant Sintilimab Plus SOX for Gastric Adenocarcinoma.Who this might be right forGastric Cancer The First Affiliated Hospital with Nanjing Medical University 90
Large-scale testing (Phase 3)Active Not RecruitingNCT01924819What this trial is testingTrial of Preoperative Therapy for Gastric and Esophagogastric Junction AdenocarcinomaWho this might be right forGastric Cancer Australasian Gastro-Intestinal Trials Group 574
Testing effectiveness (Phase 2)Study completedNCT02335411What this trial is testingPembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059)Who this might be right forGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma Merck Sharp & Dohme LLC 318
Testing effectiveness (Phase 2)Study completedNCT00917462What this trial is testingSorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction CancerWho this might be right forEsophageal CancerGastroesophageal Junction Cancer Memorial Sloan Kettering Cancer Center 35
Not applicableActive Not RecruitingNCT07663786What this trial is testingEvaluation of Esophagogastric Cancer Treatment With Nivolumab in Daily Clinical PracticeWho this might be right forEsophageal AdenocarcinomaGastro-esophageal Junction AdenocarcinomaGastric Adenocarcinoma Bristol-Myers Squibb 726
Testing effectiveness (Phase 2)Study completedNCT03529266What this trial is testingStudy of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma.Who this might be right forEsophageal CancerGastroesophageal Junction CancerAnastomotic Leak Sun Yat-sen University 57
Post-approval studies (Phase 4)Not Yet RecruitingNCT07768358What this trial is testingTucatinib Continuation StudyWho this might be right forHER2-positive Breast CancerCervical CancerBiliary Tract Neoplasms+4 more Pfizer 175
Not applicableStudy completedNCT01216813What this trial is testingStudy of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological CancerWho this might be right forAdenocarcinoma of the Gastroesophageal JunctionCervical CancerEndometrial Cancer+7 more Royal Marsden NHS Foundation Trust 33
Testing effectiveness (Phase 2)Ended earlyNCT04467515What this trial is testingEvaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) CancerWho this might be right forAdvanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment Precirix 13
Large-scale testing (Phase 3)Looking for participantsNCT04821778What this trial is testingChemoradiotherapy in Esophageal or Esophagogastric Junction CancerWho this might be right forEsophagus CancerEsophagogastric Junction CancerChemoradiation+3 more Cancer Institute and Hospital, Chinese Academy of Medical Sciences 2,000
Not applicableWithdrawnNCT00372450What this trial is testingPlastic Stents Compared With Metal Stents in Treating Patients With Malignant Dysphagia Caused by Esophageal Cancer or Gastroesophageal Junction CancerWho this might be right forEsophageal CancerGastrointestinal Complications Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Looking for participantsNCT07488676What this trial is testingASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid TumorsWho this might be right forGastric or Gastro-esophageal Junction (GEJ) AdenocarcinomaPancreatic Adenocarcinoma Astellas Pharma Global Development, Inc. 150
Testing effectiveness (Phase 2)Ended earlyNCT02241720What this trial is testingRegorafenib Second Line Treatment of Metastatic or Advanced Upper GI CancersWho this might be right forUpper GI Cancer University of Utah 5
Testing effectiveness (Phase 2)Study completedNCT03008278What this trial is testingOlaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by SurgeryWho this might be right forMetastatic Esophageal CarcinomaMetastatic Gastric CarcinomaMetastatic Gastroesophageal Junction Adenocarcinoma+10 more National Cancer Institute (NCI) 51
Testing effectiveness (Phase 2)Study completedNCT01246960What this trial is testingRamucirumab in Participants With Gastric, Esophageal, and Gastroesophageal CancerWho this might be right forStomach CancerEsophageal Cancer Eli Lilly and Company 168
Early research (Phase 1)Study completedNCT03517488What this trial is testingXmAb®20717 in Subjects With Selected Advanced Solid TumorsWho this might be right forMelanomaBreast CarcinomaHepatocellular Carcinoma+25 more Xencor, Inc. 150
Testing effectiveness (Phase 2)UnknownNCT01095120What this trial is testingTesetaxel as Second-line Therapy for Patients With Advanced Gastric CancerWho this might be right forAdenocarcinoma of the StomachAdenocarcinoma of Esophagogastric Junction Genta Incorporated 27
Testing effectiveness (Phase 2)Looking for participantsNCT07262619What this trial is testingEIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) TumorsWho this might be right forAdvanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more Eikon Therapeutics 160
Not applicableNot Yet RecruitingNCT07408999What this trial is testingTotally Versus Hybrid Minimally Invasive Esophagectomy for Esophageal CancerWho this might be right forResecable Esophageal or Gastroesophageal Junction Cancer University Hospital, Lille 327