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Results for “Gaucher Disease, Type 2”

108 trials

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Showing 20 of 108 results

Large-scale testing (Phase 3)Study completedNCT03485677
What this trial is testing

Safety and Efficacy of Eliglustat With or Without Imiglucerase in Pediatric Patients With Gaucher Disease (GD) Type 1 and Type 3

Who this might be right for
Gaucher's Disease Type IGaucher's Disease Type III
Sanofi 57
Early research (Phase 1)Active Not RecruitingNCT03635632
What this trial is testing

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Who this might be right for
Relapsed NeuroblastomaRefractory NeuroblastomaRelapsed Osteosarcoma+4 more
Baylor College of Medicine 94
Testing effectiveness (Phase 2)Ended earlyNCT04750239
What this trial is testing

Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung Cancer

Who this might be right for
SCLC
Y-mAbs Therapeutics 3
Early research (Phase 1)Study completedNCT01460901
What this trial is testing

Study of Donor Derived, Multi-virus-specific, Cytotoxic T-Lymphocytes for Relapsed/Refractory Neuroblastoma

Who this might be right for
Neuroblastoma
Children's Mercy Hospital Kansas City 5
Testing effectiveness (Phase 2)Looking for participantsNCT06026657
What this trial is testing

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8HER2-Negative Breast Carcinoma
Margaret Gatti-Mays 42
Not applicableEnrolling By InvitationNCT05368038
What this trial is testing

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program

Who this might be right for
Acid Sphingomyelinase DeficiencyCeroid Lipofuscinosis, Neuronal, 2Cerebrotendinous Xanthomatosis+11 more
Albert Einstein College of Medicine 100,000
Not applicableStudy completedNCT05641103
What this trial is testing

PREDIGA 2: Spanish Acronym of "Educational and Diagnostic Project for Gaucher and ASMD"

Who this might be right for
Gaucher DiseaseAcid SphingoMyelinase DeficiencyASMD+2 more
Fundación Española de Hematología y Hemoterapía 122
Early research (Phase 1)Study completedNCT00085930
What this trial is testing

Blood T-Cells and EBV Specific CTLs Expressing GD-2 Specific Chimeric T Cell Receptors to Neuroblastoma Patients

Who this might be right for
Neuroblastoma
Baylor College of Medicine 19
Early research (Phase 1)Looking for participantsNCT05298995
What this trial is testing

GD2-CAR T Cells for Pediatric Brain Tumours

Who this might be right for
Brain Tumor, PediatricMedulloblastoma, ChildhoodEmbryonal Tumor+4 more
Bambino Gesù Hospital and Research Institute 54
Not applicableStudy completedNCT00597272
What this trial is testing

Determine Toxicity and Antibody Responses With a KLH Conjugated Bivalent Vaccine Containing GD2 Lactone, GD3 Lactone With Immunological Adjuvant QS-DG or OPT-821 in Patients With Disease Free AJCC Stage III or IV Cutaneous Melanoma

Who this might be right for
Melanoma
Memorial Sloan Kettering Cancer Center 34
Testing effectiveness (Phase 2)UnknownNCT04637503
What this trial is testing

4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma

Who this might be right for
Neuroblastoma
Shenzhen Geno-Immune Medical Institute 100
Early research (Phase 1)Not Yet RecruitingNCT06839703
What this trial is testing

International Phase I Trial of Dinutuximab Beta With VDC/IE in GD2-Positive Ewing Sarkoma

Who this might be right for
High-risk GD2-Positive Ewing Sarcoma
Prof. Dr. Dirk Reinhardt 18
Testing effectiveness (Phase 2)Study completedNCT06438614
What this trial is testing

Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma

Who this might be right for
Refractory NeuroblastomaSoft Tissue Cancer
Fundació Sant Joan de Déu 47
Not applicableUnknownNCT02120235
What this trial is testing

Investigating Lysosomal Storage Diseases in Minority Groups

Who this might be right for
Lysosomal Storage DisordersGaucher DiseaseFabry Disease+2 more
O & O Alpan LLC 20,000
Testing effectiveness (Phase 2)UnknownNCT04429438
What this trial is testing

Multi-CAR-T Cells Targeting B Cell Lymphomas

Who this might be right for
B Cell Lymphoma (BCL)
Shenzhen Geno-Immune Medical Institute 11
Testing effectiveness (Phase 2)Study completedNCT00004184
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Melanoma (Skin)
University of Alabama at Birmingham 50
Not applicableStudy completedNCT01418495
What this trial is testing

Pharmacokinetics of Ch14.18 in Younger Patients With High-Risk Neuroblastoma

Who this might be right for
Localized Resectable NeuroblastomaLocalized Unresectable NeuroblastomaNeurotoxicity Syndrome+4 more
National Cancer Institute (NCI) 12
Early research (Phase 1)Study completedNCT02765243
What this trial is testing

Anti-GD2 4th Generation CART Cells Targeting Refractory and/or Recurrent Neuroblastoma

Who this might be right for
NeuroblastomaEffects of Immunotherapy
Zhujiang Hospital 12
Large-scale testing (Phase 3)Study completedNCT00224484
What this trial is testing

Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old

Who this might be right for
Herpes Simplex
GlaxoSmithKline 5,960
Testing effectiveness (Phase 2)Looking for participantsNCT06739226
What this trial is testing

Combination Immunotherapy Targeting Melanoma

Who this might be right for
Melanoma
Shenzhen Geno-Immune Medical Institute 30
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