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Results for “Gene Amplification”

313 trials

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Showing 20 of 313 results

Early research (Phase 1)Study completedNCT01613950
What this trial is testing

PI3K Inhibitor BYL719 in Combination With the HSP90 Inhibitor AUY922 in Patients With Advanced or Metastatic Gastric Cancer

Who this might be right for
Stomach Neoplasms Esophageal Neoplasms Metastatic Gastric Cancer Mutated PI3KCA Protein Overexpressed HER2 Protein
Novartis Pharmaceuticals 18
Testing effectiveness (Phase 2)UnknownNCT05016544
What this trial is testing

Inetetamab in Combination With Pyrotinib in HER2 Mutant or Amplified Advanced Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944772
What this trial is testing

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 247
Testing effectiveness (Phase 2)Study completedNCT02447419
What this trial is testing

Study to Evaluate the Safety and Efficacy of Gefitinib, in Subjects With EFGR Amplification Refractory Solid Tumors

Who this might be right for
Solid Tumor
Samsung Medical Center 16
Large-scale testing (Phase 3)Study completedNCT00025428
What this trial is testing

Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma

Who this might be right for
Neuroblastoma
Societe Internationale d'Oncologie Pediatrique 100
Testing effectiveness (Phase 2)UnknownNCT05163249
What this trial is testing

Osimertinib With or Without Savolitinib as 1L in de Novo MET+, EGFR+ NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Guangdong Association of Clinical Trials 44
Not applicableStudy completedNCT04222296
What this trial is testing

Bimodal, CROS and Severe Profound Hearing Loss Study

Who this might be right for
Cochlear ImplantSevere-Profound Hearing LossHearing Loss, Bilateral+1 more
Cambridge University Hospitals NHS Foundation Trust 30
Not applicableStudy completedNCT03652909
What this trial is testing

Personal Sound Amplification Smartphone Application Feasibility

Who this might be right for
Hearing Loss
Medical College of Wisconsin 32
Not applicableLooking for participantsNCT05703516
What this trial is testing

A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea

Who this might be right for
Non-Small-Cell Lung Carcinoma
Novartis Pharmaceuticals 44
Not applicableUnknownNCT03362827
What this trial is testing

Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients

Who this might be right for
Low Back Pain
Peking University People's Hospital 50
Testing effectiveness (Phase 2)Ended earlyNCT05497453
What this trial is testing

Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene

Who this might be right for
Hepatocellular CarcinomaSolid TumorHepatocellular Carcinoma Non-resectable+4 more
Omega Therapeutics 24
Early research (Phase 1)WithdrawnNCT05510427
What this trial is testing

Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/Amplification

Who this might be right for
CholangiocarcinomaLiver Cancer
M.D. Anderson Cancer Center
Not applicableWithdrawnNCT02294045
What this trial is testing

Analysis of Joint Sounds in the Diagnosis of Knee Disorders

Who this might be right for
Arthritis of KneeNormal KneeKnee Arthroscopy
Loma Linda University
Not applicableStudy completedNCT05902494
What this trial is testing

HER2 and LA/mUC: A Multi-country Chart Review Cohort Study

Who this might be right for
Urothelial Carcinoma
Seagen, a wholly owned subsidiary of Pfizer 389
Testing effectiveness (Phase 2)Active Not RecruitingNCT06136897
What this trial is testing

Testing Trastuzumab and Pertuzumab in Patients With Higher Than Normal Copies of the HER2 Gene Found in Their Tumors (MATCH - Subprotocol J)

Who this might be right for
Malignant Solid Neoplasm
National Cancer Institute (NCI) 35
Large-scale testing (Phase 3)Study completedNCT00047255
What this trial is testing

Docetaxel and Trastuzumab With or Without Carboplatin in Treating Women With HER2-Positive Breast Cancer

Who this might be right for
Breast Cancer
Jonsson Comprehensive Cancer Center 263
Testing effectiveness (Phase 2)UnknownNCT05274191
What this trial is testing

An Exploratory Basket Study of Pyrotinib Maleate Tablets in HER2 Mutated or Amplified of Metastatic Solid Tumors

Who this might be right for
Solid Tumor
Zhongshan Hospital Xiamen University 60
Testing effectiveness (Phase 2)Looking for participantsNCT05800340
What this trial is testing

Neoadjuvant Immunotherapy in Rare Mutations Localized NSCLC

Who this might be right for
Non-Small Cell Lung CancerRET Driver MutationBRAF V600 Mutation+3 more
Guangdong Provincial People's Hospital 30
Not applicableStudy completedNCT02826291
What this trial is testing

SLNM in Endometrial Cancer Combined With OSNA

Who this might be right for
Endometrial Cancer
Charles University, Czech Republic 58
Testing effectiveness (Phase 2)Looking for participantsNCT06947291
What this trial is testing

Safety and Efficacy of Glumetinib Combined With Docetaxel for Injection (Albumin-bound) in Patients With Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors

Who this might be right for
Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma and Other Solid Tumors
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 350
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