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Results for “Gene Deletion”

60 trials

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Showing 20 of 60 results

Not applicableStudy completedNCT05306067
What this trial is testing

Plasmodium Falciparum Genomic Intelligence in Mozambique

Who this might be right for
Malaria,FalciparumMalaria in PregnancyMalaria
Centro de Investigacao em Saude de Manhica 21,848
Early research (Phase 1)Not Yet RecruitingNCT07511062
What this trial is testing

Axatilimab Combined With Decitabine/Venetoclax for the Treatment of TP53-mutated AML

Who this might be right for
Acute Myeloid LeukemiaTP53 Gene Mutation
Northside Hospital, Inc. 32
Early research (Phase 1)Ended earlyNCT05153408
What this trial is testing

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Who this might be right for
Lung NeoplasmCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+24 more
Blueprint Medicines Corporation 20
Testing effectiveness (Phase 2)UnknownNCT04042831
What this trial is testing

Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Who this might be right for
Bile Duct AdenocarcinomaFanconi Anemia Complementation Group Gene MutationMetastatic Bile Duct Carcinoma+1 more
Academic and Community Cancer Research United 36
Not applicableActive Not RecruitingNCT02692872
What this trial is testing

Screening for Alpha Thalassemia in Healthy Volunteers

Who this might be right for
Alpha Thalassemia
National Institute of Allergy and Infectious Diseases (NIAID) 367
Not applicableEnded earlyNCT02527954
What this trial is testing

Aneuploidies in Embryos and Spermatozoa From Patients With Y-chromosome Microdeletions

Who this might be right for
Male Sterility Due to Y-chromosome Deletions
Instituto Valenciano de Infertilidad, IVI Alicante 5
Early research (Phase 1)Ended earlyNCT04862780
What this trial is testing

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

Who this might be right for
Lung NeoplasmsCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+21 more
Blueprint Medicines Corporation 177
Not applicableStudy completedNCT00105274
What this trial is testing

Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study

Who this might be right for
DiGeorge SyndromeVelocardiofacial Syndrome22q11.2 Syndrome
National Institute of Mental Health (NIMH)
Not applicableUnknownNCT04997629
What this trial is testing

Gene Biobank of Sports Injuries

Who this might be right for
Gene InsertionsGene Deletion
Peking University Third Hospital 10,000
Testing effectiveness (Phase 2)Study completedNCT02061384
What this trial is testing

RA-2 13-cis Retinoic Acid (Isotretinoin)

Who this might be right for
Male InfertilityKlinefelter's SyndromeY-chromosome Microdeletions
University of Washington 20
Not applicableLooking for participantsNCT04025515
What this trial is testing

Molecular Profiling Project

Who this might be right for
Lung CancerNon-Small Cell Lung Cancer
National Cancer Centre, Singapore 500
Not applicableLooking for participantsNCT02573636
What this trial is testing

The Predictive Value of Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate Cancer Patients with Biochemical Failure Status Post Salvage or Radical Radiation Therapy

Who this might be right for
Prostate Cancer
Sir Mortimer B. Davis - Jewish General Hospital 208
Not applicableUnknownNCT04701229
What this trial is testing

Haploinsufficiency of the RBM22 and SLU7 Genes in Del(5q) Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic SyndromesMyelodysplastic Syndrome With Isolated Del(5Q)Myelodysplastic Syndrome With Del(5Q)
University Hospital, Brest 100
Not applicableNot Yet RecruitingNCT06662591
What this trial is testing

Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study

Who this might be right for
Autism Spectrum Disorder (ASD)
Research and Treatment Society of Genetic Disorders 3,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT03588299
What this trial is testing

Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle"

Who this might be right for
Hemophilia A
Bayer 11
Not applicableLooking for participantsNCT06659458
What this trial is testing

Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

Who this might be right for
Lung Cancer - Non Small CellEGFR Exon 19 Deletion Mutation
Our Lady of the Lake Hospital 20
Not applicableUnknownNCT05713721
What this trial is testing

Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes

Who this might be right for
ParkinsonDystoniaDYT3+3 more
University Hospital Schleswig-Holstein 120
Very early researchEnded earlyNCT03272633
What this trial is testing

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia in RemissionHematopoietic Cell Transplantation Recipient+16 more
Rutgers, The State University of New Jersey 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT02286687
What this trial is testing

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

Who this might be right for
Advanced Malignant NeoplasmATM Gene MutationBRCA1 Gene Mutation+5 more
M.D. Anderson Cancer Center 150
Testing effectiveness (Phase 2)Study completedNCT00159250
What this trial is testing

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Who this might be right for
Duchenne Muscular Dystrophy
Imperial College London 7
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