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Results for “Gene Deletion”

62 trials

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Showing 20 of 62 results

Not applicableActive Not RecruitingNCT02692872
What this trial is testing

Screening for Alpha Thalassemia in Healthy Volunteers

Who this might be right for
Alpha Thalassemia
National Institute of Allergy and Infectious Diseases (NIAID) 367
Large-scale testing (Phase 3)WithdrawnNCT06297486
What this trial is testing

Study of a Gene Therapy Treatment for Hemophilia A

Who this might be right for
Hemophilia A
Spark Therapeutics, Inc.
Not applicableLooking for participantsNCT05653544
What this trial is testing

Natural History in Primary Mitochondrial Myopathies

Who this might be right for
Primary Mitochondrial Myopathies
Cristina Domínguez González 150
Not applicableStudy completedNCT00758108
What this trial is testing

Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions

Who this might be right for
WAGR SyndromeWilm's TumorAniridia+2 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 197
Not applicableNot Yet RecruitingNCT06907550
What this trial is testing

Mitochondrial DNA Deletions in Plasma as a Diagnostic Aid for Females Presenting With Symptoms of Endometriosis

Who this might be right for
Endometriosis
Pearsanta, Inc 1,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT02286687
What this trial is testing

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

Who this might be right for
Advanced Malignant NeoplasmATM Gene MutationBRCA1 Gene Mutation+5 more
M.D. Anderson Cancer Center 150
Not applicableStudy completedNCT00001642
What this trial is testing

Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

Who this might be right for
Alagille Syndrome
National Human Genome Research Institute (NHGRI) 225
Not applicableUnknownNCT04701229
What this trial is testing

Haploinsufficiency of the RBM22 and SLU7 Genes in Del(5q) Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic SyndromesMyelodysplastic Syndrome With Isolated Del(5Q)Myelodysplastic Syndrome With Del(5Q)
University Hospital, Brest 100
Not applicableUnknownNCT00161109
What this trial is testing

Genetics and Psychopathology in the 22q11 Deletion Syndrome

Who this might be right for
Chromosome 22q11.2 Deletion Syndrome
UMC Utrecht 175
Early research (Phase 1)Looking for participantsNCT07361562
What this trial is testing

A Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, AdultERBB2 Altered Breast CancerERBB2 Gene Amplification+3 more
Cogent Biosciences, Inc. 100
Not applicableUnknownNCT04093609
What this trial is testing

XIST Gene Deletion in Breast Cancer Therapy

Who this might be right for
Breast Cancer
Assiut University 1
Not applicableUnknownNCT04997629
What this trial is testing

Gene Biobank of Sports Injuries

Who this might be right for
Gene InsertionsGene Deletion
Peking University Third Hospital 10,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT04042831
What this trial is testing

Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Who this might be right for
Bile Duct AdenocarcinomaFanconi Anemia Complementation Group Gene MutationMetastatic Bile Duct Carcinoma+1 more
Academic and Community Cancer Research United 32
Not applicableUnknownNCT02317965
What this trial is testing

Non-Invasive Screening for Fetal Aneuploidy

Who this might be right for
Down SyndromeEdwards Syndrome
Progenity, Inc. 340
Post-approval studies (Phase 4)Study completedNCT02514174
What this trial is testing

Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older

Who this might be right for
Carcinoma, Non-Small-Cell LungErbB Receptors
Boehringer Ingelheim 25
Large-scale testing (Phase 3)Study completedNCT02980731
What this trial is testing

A Study Evaluating the Impact of Venetoclax on the Quality of Life for Subjects With Relapsed (Your Cancer Has Come Back) or Refractory (no Response to Previous Cancer Treatments) Chronic Lymphocytic Leukemia (CLL) While Receiving Venetoclax Monotherapy (a Single Agent).

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)
AbbVie 210
Testing effectiveness (Phase 2)Looking for participantsNCT06630416
What this trial is testing

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

Who this might be right for
Metastatic Bladder Urothelial CarcinomaMetastatic Malignant Solid NeoplasmStage IV Bladder Cancer AJCC v8+1 more
Northwestern University 64
Testing effectiveness (Phase 2)Study completedNCT00159250
What this trial is testing

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Who this might be right for
Duchenne Muscular Dystrophy
Imperial College London 7
Not applicableUnknownNCT05713721
What this trial is testing

Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes

Who this might be right for
ParkinsonDystoniaDYT3+3 more
University Hospital Schleswig-Holstein 120
Testing effectiveness (Phase 2)UnknownNCT00457314
What this trial is testing

The Effects of Exercise Versus Inactivity on People With Mitochondrial Muscle Disease

Who this might be right for
Mitochondrial Myopathy
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 50
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