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Results for “Gene Insertions”

13 trials

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Showing 13 of 13 results

Testing effectiveness (Phase 2)Looking for participantsNCT06379789
What this trial is testing

Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

Who this might be right for
Hemophilia B
Regeneron Pharmaceuticals 130
Not applicableUnknownNCT04997629
What this trial is testing

Gene Biobank of Sports Injuries

Who this might be right for
Gene InsertionsGene Deletion
Peking University Third Hospital 10,000
Post-approval studies (Phase 4)WithdrawnNCT03311074
What this trial is testing

Retroviral Insertion Site Methodology Study

Who this might be right for
Immune System Diseases
Fondazione Telethon
Early research (Phase 1)Ended earlyNCT04209465
What this trial is testing

BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.

Who this might be right for
Solid Tumor
Black Diamond Therapeutics, Inc. 91
Testing effectiveness (Phase 2)Ended earlyNCT02702115
What this trial is testing

Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-318 in Subjects With MPS I

Who this might be right for
MPS I
Sangamo Therapeutics 3
Not applicableNot Yet RecruitingNCT06662591
What this trial is testing

Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study

Who this might be right for
Autism Spectrum Disorder (ASD)
Research and Treatment Society of Genetic Disorders 3,000
Testing effectiveness (Phase 2)Ended earlyNCT03041324
What this trial is testing

Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-913 in Subjects With MPS II

Who this might be right for
Mucopolysaccharidosis IIMPS II
Sangamo Therapeutics 9
Testing effectiveness (Phase 2)Ended earlyNCT03805841
What this trial is testing

Study of Tarloxotinib in Pts With NSCLC (EGFR Exon 20 Insertion, HER2-activating Mutations) & Other Solid Tumors With NRG1/ERBB Gene Fusions

Who this might be right for
NSCLC, Stage IVNSCLC Stage IIIBNSCLC, Stage IIIC+5 more
Rain Oncology Inc 41
Not applicableWithdrawnNCT05737849
What this trial is testing

Learn About the Tests Looking for a Gene Mutation in Adults With Lung Cancer in China (ELEGANT)

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Takeda
Not applicableUnknownNCT04959890
What this trial is testing

Methodology Study of Retroviral Insertion Site Analysis in Strimvelis Gene Therapy

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
Fondazione Telethon 15
Early research (Phase 1)Looking for participantsNCT07361562
What this trial is testing

A Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, AdultERBB2 Altered Breast CancerERBB2 Gene Amplification+3 more
Cogent Biosciences, Inc. 100
Not applicableLooking for participantsNCT04025515
What this trial is testing

Molecular Profiling Project

Who this might be right for
Lung CancerNon-Small Cell Lung Cancer
National Cancer Centre, Singapore 500
Not applicableStudy completedNCT04268030
What this trial is testing

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

Who this might be right for
Parkinson Disease
Rush University Medical Center 9