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Results for “Gene Mutation-Related Cancer”

116 trials

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Showing 20 of 116 results

Testing effectiveness (Phase 2)WithdrawnNCT05041972
What this trial is testing

ARX788 in Selected HER2-mutated or HER2-amplified/Overexpressed Solid Tumors (ACE-Pan Tumor-02)

Who this might be right for
HER2 Mutation-Related TumorsHER2 Amplified Solid Tumors
Ambrx, Inc.
Not applicableUnknownNCT05136014
What this trial is testing

Evaluation of the Response to Tyrosine Kinase Inhibitors in Localized Non-small Cell Lung Cancer (NSCLC) Patients With EGFR Mutation in a Patient-derived Organoid Model

Who this might be right for
Lung CancerLung AdenocarcinomaEGFR Activating Mutation+2 more
Central Hospital, Nancy, France 200
Not applicableStudy completedNCT04651920
What this trial is testing

A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerChineseHomologous Recombination Deficiency+4 more
Lei Li 240
Testing effectiveness (Phase 2)UnknownNCT06237413
What this trial is testing

ZG2001 in Participants With KRAS Mutated Advanced Solid Tumours

Who this might be right for
Solid TumorKRAS Mutation-Related Tumors
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 110
Not applicableEnrolling By InvitationNCT06807515
What this trial is testing

Pilot Observational Study and Safety Analysis of FL Nourish Capsules in Cancer Patients in Remission

Who this might be right for
CancerCancer Survivor
Thong Chai Institute of Medical Research 24
Not applicableUnknownNCT04524260
What this trial is testing

The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients

Who this might be right for
Lower Gastrointestinal Neoplasms BenignPancreas CancerPosttraumatic Stress Disorder+1 more
University of Zurich 80
Testing effectiveness (Phase 2)Looking for participantsNCT07148128
What this trial is testing

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Who this might be right for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic AdenocarcinomaAdvanced or Metastatic KRAS-mutant Tumor in Colorectal CancerAdvanced or Metastatic KRAS-mutant Tumor in Non Small Cell Lung Cancer+2 more
Auricula Biosciences Inc.
Not applicableLooking for participantsNCT01247597
What this trial is testing

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

Who this might be right for
Pleuropulmonary BlastomaCystic NephromaOvarian Sertoli-Leydig Cell Tumors+2 more
National Cancer Institute (NCI) 1,500
Early research (Phase 1)WithdrawnNCT04602117
What this trial is testing

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

Who this might be right for
HER2-positive Breast CancerHER2 LowSYD-985+24 more
QuantumLeap Healthcare Collaborative
Testing effectiveness (Phase 2)Active Not RecruitingNCT04238624
What this trial is testing

Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer

Who this might be right for
Anaplastic Thyroid CancerThyroid CancerBRAF Gene Mutation+1 more
Memorial Sloan Kettering Cancer Center 16
Not applicableStudy completedNCT03424213
What this trial is testing

Race-related Alternative Splicing: Novel Targets in Prostate Cancer

Who this might be right for
Prostate Cancer
Duke University 169
Not applicableActive Not RecruitingNCT06497270
What this trial is testing

A 3D Bioprinted Hormone-producing Model for BRCA Mutated Patients After Risk Reducing Surgery: the DISC-OVARY Trial

Who this might be right for
BRCA MutationEstrogen DeficiencySurgical Menopause+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 3
Not applicableLooking for participantsNCT05512169
What this trial is testing

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia

Who this might be right for
ALL, ChildhoodPediatric CancerToxicity, Drug+5 more
University of Geneva, Switzerland 556
Not applicableStudy completedNCT04425200
What this trial is testing

Prevalence of HRR-related Genes Mutations and Prognosis in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients in Real World Setting

Who this might be right for
Prostatic Neoplasms
AstraZeneca 205
Not applicableLooking for participantsNCT04395495
What this trial is testing

RASopathy Biorepository

Who this might be right for
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Children's Hospital Medical Center, Cincinnati 1,000
Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Post-approval studies (Phase 4)Looking for participantsNCT05183828
What this trial is testing

Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+2 more
University of Washington 68
Not applicableStudy completedNCT04976439
What this trial is testing

Patogenic Mutation in 5 Genes

Who this might be right for
Colorectal CancerAPC Gene MutationTP53 Gene Mutation+3 more
Dr Cipto Mangunkusumo General Hospital 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT03330847
What this trial is testing

To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

Who this might be right for
Metastatic Triple Negative Breast Cancer
AstraZeneca 273
Testing effectiveness (Phase 2)Study completedNCT02553642
What this trial is testing

Relationship Between Tumor Mutation Burden and Predicted Neo-antigen Burden in Patients With Advanced Melanoma or Bladder Cancer Treated With Nivolumab or Nivolumab Plus Ipilimumab (CA209-260)

Who this might be right for
Bladder CancerMelanoma
Memorial Sloan Kettering Cancer Center 81
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