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Results for “Gene Mutations”

2,085 trials

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Showing 20 of 2,085 results

Testing effectiveness (Phase 2)Looking for participantsNCT06383533
What this trial is testing

Disitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct Adenocarcinoma

Who this might be right for
Bile Duct Adenocarcinoma Non-ResectableHER2 Gene Mutation
Zhejiang Cancer Hospital 28
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Testing effectiveness (Phase 2)Ended earlyNCT01857271
What this trial is testing

Erlotinib Hydrochloride Before Surgery in Treating Patients With Stage III Non-Small Cell Lung Cancer

Who this might be right for
Stage IIIA Non-Small Cell Lung CancerStage IIIB Non-Small Cell Lung Cancer
Albert Einstein College of Medicine 3
Not applicableStudy completedNCT04425200
What this trial is testing

Prevalence of HRR-related Genes Mutations and Prognosis in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients in Real World Setting

Who this might be right for
Prostatic Neoplasms
AstraZeneca 205
Testing effectiveness (Phase 2)Study completedNCT00827684
What this trial is testing

Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations

Who this might be right for
Metastatic Colorectal Cancer
Vejle Hospital 50
Not applicableStudy completedNCT01773655
What this trial is testing

Clinical and Histopathologic Characteristics of BAP1 Mutations

Who this might be right for
Malignant Pleural Mesothelioma (MPM)Choroidal NevusPrimary Uveal Melanoma (UM)+3 more
Memorial Sloan Kettering Cancer Center 196
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05232006
What this trial is testing

PARP-inhibitor on Advanced Metastatic Breast Cancer in Germline PALB2 Mutations Carriers

Who this might be right for
Metastatic Breast Cancer in Germline-PALB2 Mutations Carriers
Assistance Publique - Hôpitaux de Paris 12
Testing effectiveness (Phase 2)Looking for participantsNCT07294144
What this trial is testing

Tofersen in Non-SOD1 ALS

Who this might be right for
ALS (Amyotrophic Lateral Sclerosis)
Washington University School of Medicine 30
Not applicableUnknownNCT02738684
What this trial is testing

Predict Gefitinib' s Efficacy for Lung Cancer by Plasma Free Nucleic Acids EGFR Gene Mutation Test

Who this might be right for
Lung Adenocarcinoma
Southwest Hospital, China 100
Not applicableActive Not RecruitingNCT04285398
What this trial is testing

Prospective Natural History Study of Retinitis Pigmentosa

Who this might be right for
Retinitis Pigmentosa
SparingVision 82
Testing effectiveness (Phase 2)Study completedNCT02321540
What this trial is testing

A Phase I/II Study of Ibrutinib in Previously Treated Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
M.D. Anderson Cancer Center 13
Large-scale testing (Phase 3)Not Yet RecruitingNCT06335355
What this trial is testing

A Phase II/III Study of Adebrelimab in Combination With SHR-8068 and Chemotherapy in Advanced or Metastatic NSCLC Patients

Who this might be right for
Non-squamous Non-small Cell Lung Cancer
Shanghai Shengdi Pharmaceutical Co., Ltd 401
Large-scale testing (Phase 3)Study completedNCT02965378
What this trial is testing

Lung-MAP: AZD4547 as Second-Line Therapy in Treating FGFR Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
FGFR1 Gene AmplificationFGFR1 Gene MutationFGFR2 Gene Amplification+5 more
SWOG Cancer Research Network 43
Testing effectiveness (Phase 2)Study completedNCT04174716
What this trial is testing

Basket Trial of IDX-1197, a PARP Inhibitor, in Patients with HRR Mutated Solid Tumors (VASTUS)

Who this might be right for
Solid TumorsHomologous Recombination Repair Gene MutationHomologous Recombination Deficiency
Idience Co., Ltd. 108
Not applicableLooking for participantsNCT03193476
What this trial is testing

Registry for Patients With X-Linked Hypophosphatemia

Who this might be right for
X-Linked Hypophosphatemia
Kyowa Kirin Pharmaceutical Development Ltd 1,343
Not applicableStudy completedNCT00999947
What this trial is testing

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

Who this might be right for
CardiomyopathyArrhythmogenic Right Ventricular Dysplasia
Assistance Publique - Hôpitaux de Paris 351
Not applicableEnded earlyNCT03127449
What this trial is testing

AST2818 in Advanced Non-Small Cell Lung Cancer With EGFR Mutations

Who this might be right for
Advanced NSCLC
Allist Pharmaceuticals, Inc. 116
Large-scale testing (Phase 3)Not Yet RecruitingNCT06380348
What this trial is testing

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Who this might be right for
Local Advanced or Metastatic NSCLC
Shanghai JMT-Bio Inc. 398
Testing effectiveness (Phase 2)Study completedNCT00109590
What this trial is testing

Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 175
Testing effectiveness (Phase 2)Study completedNCT02676843
What this trial is testing

Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

Who this might be right for
Frontotemporal Lobar Degeneration (FTLD)Frontotemporal Dementia (FTD)Tauopathies
Columbia University 7
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