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Results for “Gene Transfer”

1,099 trials

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Enrolling by Invitation

Showing 20 of 1,099 results

Testing effectiveness (Phase 2)Enrolling By InvitationNCT03999801
What this trial is testing

Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

Who this might be right for
Neovascular Age-related Macular DegenerationWet Macular Degeneration
AbbVie 865
Testing effectiveness (Phase 2)WithdrawnNCT02390739
What this trial is testing

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing Human Thyroglobulin to People With Thyroglobulin Expressing Thyroid Cancer

Who this might be right for
Metastatic Thyroid Cancer
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT06399107
What this trial is testing

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle-Cell Disease With Crisis
Essen Biotech 85
Testing effectiveness (Phase 2)Study completedNCT00001493
What this trial is testing

Antimetabolite Induction, High-Dose Alkylating Agent Consolidation and Retroviral Transduction of the MDR1 Gene Into Peripheral Blood Progenitor Cells Followed by Intensification Therapy With Sequential Paclitaxel and Doxorubicin for Stage 4 Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasm Metastasis
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Study completedNCT02556736
What this trial is testing

AGN-151597 (Formerly RST-001) Phase I/II Trial for Advanced Retinitis Pigmentosa

Who this might be right for
Advanced Retinitis Pigmentosa
AbbVie 14
Early research (Phase 1)Ended earlyNCT00072098
What this trial is testing

Interleukin-12 Gene in Treating Patients With Liver Metastases Secondary to Colorectal Cancer

Who this might be right for
Colorectal CancerMetastatic Cancer
Max Sung 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT04069533
What this trial is testing

Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A

Who this might be right for
Fanconi Anemia Complementation Group A
Rocket Pharmaceuticals Inc. 7
Testing effectiveness (Phase 2)WithdrawnNCT06690281
What this trial is testing

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

Who this might be right for
Gastrointestinal CarcinomaPancreatic CancerHepatocellular Cancer+5 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT00019136
What this trial is testing

Gene Therapy and Biological Therapy in Treating Patients With Ovarian Epithelial Cancer

Who this might be right for
Ovarian Cancer
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)WithdrawnNCT01531244
What this trial is testing

Isolated Limb Infusion Chemotherapy With Targeted Gene Therapy for Advanced, Unresectable Extremity Melanoma

Who this might be right for
Melanoma
Washington University School of Medicine
Very early researchNot Yet RecruitingNCT06178432
What this trial is testing

Evaluation of the Safety, Tolerability and Efficacy of Gene Therapy Drug for Late Onset Pompe Disease (LOPD)

Who this might be right for
Pompe Disease (Late-onset)
Huashan Hospital 6
Testing effectiveness (Phase 2)Study completedNCT00300521
What this trial is testing

Liver Transplantation With ADV-TK Gene Therapy Improves Survival in Patients With Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaLiver Transplantation
Beijing Chao Yang Hospital 40
Very early researchNot Yet RecruitingNCT06963008
What this trial is testing

A Prospective, Single-center, Open-label Clinical Study to Evaluate the Safety and Efficacy of Inhaled BMD003(CFTR mRNA) in Chinese Adult Patients With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis (CF)Gene Therapy
Peking Union Medical College Hospital 12
Early research (Phase 1)Ended earlyNCT01952730
What this trial is testing

Pilot Study of GVAX in Colorectal Cancer Cells

Who this might be right for
Colorectal Cancer
Massachusetts General Hospital 1
Large-scale testing (Phase 3)Active Not RecruitingNCT00999609
What this trial is testing

Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis

Who this might be right for
Inherited Retinal Dystrophy Due to RPE65 MutationsLeber Congenital Amaurosis
Spark Therapeutics, Inc. 31
Early research (Phase 1)Active Not RecruitingNCT03635632
What this trial is testing

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Who this might be right for
Relapsed NeuroblastomaRefractory NeuroblastomaRelapsed Osteosarcoma+4 more
Baylor College of Medicine 94
Not applicableStudy completedNCT00001353
What this trial is testing

Safety and Survival of Genetically Modified White Blood Cells in HIV-Infected Persons - A Study in Identical Twin Pairs

Who this might be right for
Acquired Immunodeficiency SyndromeHIV Infection
National Institute of Allergy and Infectious Diseases (NIAID) 24
Large-scale testing (Phase 3)Study completedNCT03496012
What this trial is testing

Efficacy and Safety of BIIB111 for the Treatment of Choroideremia

Who this might be right for
Choroideremia
Biogen 169
Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Early research (Phase 1)Ended earlyNCT04443907
What this trial is testing

Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)

Who this might be right for
Sickle Cell Disease
Novartis Pharmaceuticals 4
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