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Results for “Gene Transfer”

1,140 trials

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Showing 20 of 1,140 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05407636
What this trial is testing

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

Who this might be right for
AMDnAMDWet Age-related Macular Degeneration+3 more
AbbVie 735
Testing effectiveness (Phase 2)Active Not RecruitingNCT03326336
What this trial is testing

Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa

Who this might be right for
Non-syndromic Retinitis Pigmentosa
GenSight Biologics 10
Not applicableStudy completedNCT01416467
What this trial is testing

Characterization of the Patient Population With Galactosialidosis

Who this might be right for
Galactosialidosis
St. Jude Children's Research Hospital 3
Early research (Phase 1)Looking for participantsNCT06885697
What this trial is testing

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Who this might be right for
MesotheliomaNeoplasmsStomach Neoplasms+5 more
National Cancer Institute (NCI) 100
Testing effectiveness (Phase 2)Ended earlyNCT06716853
What this trial is testing

A Clinical Gene Therapy Study With Hematopoietic Stem Cells for the Treatment, With Single Dose of Temferon, of Patients Suffering From Metastatic Renal Cell Carcinoma

Who this might be right for
Clear Cell RCC
Genenta Science 10
Large-scale testing (Phase 3)Active Not RecruitingNCT05606614
What this trial is testing

A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)

Who this might be right for
Rett Syndrome
Taysha Gene Therapies, Inc. 17
Early research (Phase 1)Study completedNCT00403221
What this trial is testing

Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer

Who this might be right for
Prostatic Neoplasms
Baylor College of Medicine 19
Early research (Phase 1)Study completedNCT00003588
What this trial is testing

Gene Therapy in Treating Patients With Ovarian Cancer

Who this might be right for
Ovarian Cancer
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)WithdrawnNCT06297486
What this trial is testing

Study of a Gene Therapy Treatment for Hemophilia A

Who this might be right for
Hemophilia A
Spark Therapeutics, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT05824169
What this trial is testing

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 1 Patients

Who this might be right for
Spinal Muscular Atrophy
GeneCradle Inc 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT04201405
What this trial is testing

Gene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type IIIA

Who this might be right for
Mucopolysaccharidosis Type IIIA
University of Manchester 5
Early research (Phase 1)Study completedNCT05144386
What this trial is testing

Study of EBT-101 in Aviremic HIV-1 Infected Adults on Stable ART

Who this might be right for
HIV-1-infection
Excision BioTherapeutics 6
Testing effectiveness (Phase 2)WithdrawnNCT05778877
What this trial is testing

Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA

Who this might be right for
Methylmalonic Acidemia (MMA)
Selecta Biosciences, Inc.
Early research (Phase 1)Looking for participantsNCT05686798
What this trial is testing

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Who this might be right for
Malignant Glioma of BrainAstrocytomaMalignant Astrocytoma+6 more
Henry Ford Health System 18
Testing effectiveness (Phase 2)Ended earlyNCT00924287
What this trial is testing

Gene Therapy Using Anti-Her-2 Cells to Treat Metastatic Cancer

Who this might be right for
Metastatic Cancer
National Cancer Institute (NCI) 1
Early research (Phase 1)Ended earlyNCT05062980
What this trial is testing

Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-Small Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Genprex, Inc. 5
Testing effectiveness (Phase 2)Looking for participantsNCT03412877
What this trial is testing

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

Who this might be right for
Endocrine TumorsNon-Small Cell Lung CancerOvarian Cancer+4 more
National Cancer Institute (NCI) 285
Not applicableStudy completedNCT04312672
What this trial is testing

Long-term Follow-up Gene Therapy Study for RPGR- XLRP

Who this might be right for
X-Linked Retinitis Pigmentosa
Janssen Research & Development, LLC 42
Testing effectiveness (Phase 2)Ended earlyNCT01856439
What this trial is testing

Long Term Safety and Efficacy Study of ProSavin in Parkinson's Disease

Who this might be right for
Parkinson's Disease
Axovant Sciences Ltd. 15
Testing effectiveness (Phase 2)Study completedNCT02991144
What this trial is testing

Safety and Dose-Finding Study of DTX301 (scAAV8OTC) in Adults With Late-Onset Ornithine Transcarbamylase (OTC) Deficiency

Who this might be right for
Ornithine Transcarbamylase (OTC) Deficiency
Ultragenyx Pharmaceutical Inc 16
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