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Results for “Generalized Myasthenia Gravis (gMG)”

56 trials

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Showing 20 of 56 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05644561
What this trial is testing

Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia GravisgMG
Alexion Pharmaceuticals, Inc. 12
Large-scale testing (Phase 3)Study completedNCT03759366
What this trial is testing

Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)

Who this might be right for
Myasthenia GravisMyasthenia Gravis, Juvenile FormMyasthenia Gravis, Generalized
Alexion Pharmaceuticals, Inc. 12
Early research (Phase 1)Not Yet RecruitingNCT07818291
What this trial is testing

An Open-label, Dose-escalation Phase Ib Study of EA5 Injection in Adults With Anti-AChR Antibody-Positive Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis (gMG)
Shanghai Lanyi Therapeutics Co., Ltd. 18
Large-scale testing (Phase 3)Looking for participantsNCT06744920
What this trial is testing

Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis
Novartis Pharmaceuticals 180
Post-approval studies (Phase 4)Looking for participantsNCT07246564
What this trial is testing

Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
UCB Biopharma SRL 40
Testing effectiveness (Phase 2)Looking for participantsNCT06987539
What this trial is testing

Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG)

Who this might be right for
Generalized Myasthenia Gravis
Amgen 15
Large-scale testing (Phase 3)Active Not RecruitingNCT06149559
What this trial is testing

Rozanolixizumab in Pediatric Study Participants With Moderate to Severe Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis
UCB Biopharma SRL 14
Post-approval studies (Phase 4)Looking for participantsNCT07221838
What this trial is testing

Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab

Who this might be right for
Generalized Myasthenia GravisgMG
Alexion Pharmaceuticals, Inc. 75
Large-scale testing (Phase 3)Looking for participantsNCT07596784
What this trial is testing

Efficacy and Safety of Ravulizumab in Chinese Adults Participants With Generalized Myasthenia Gravis (gMG)

Who this might be right for
Generalized Myasthenia GravisgMG
Alexion Pharmaceuticals, Inc. 20
Testing effectiveness (Phase 2)Looking for participantsNCT06359041
What this trial is testing

RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis (gMG)
Cabaletta Bio 24
Large-scale testing (Phase 3)Study completedNCT02301624
What this trial is testing

Extension Study of ECU-MG-301 to Evaluate Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis

Who this might be right for
Refractory Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 117
Early research (Phase 1)Active Not RecruitingNCT06220201
What this trial is testing

Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

Who this might be right for
Multiple SclerosisMyasthenia Gravis
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 120
Large-scale testing (Phase 3)Enrolling By InvitationNCT06540144
What this trial is testing

An Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis
UCB Biopharma SRL 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04146051
What this trial is testing

Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

Who this might be right for
Myasthenia Gravis, Generalized
Cartesian Therapeutics 30
Not applicableNot Yet RecruitingNCT06827587
What this trial is testing

Efficacy and Safety of Efgartigimod Sequential Therapy with Telitacicept in Generalized Myasthenia Gravis

Who this might be right for
Myasthenia GravisAutoimmune DiseasesNeuromuscular Diseases
First Affiliated Hospital of Wenzhou Medical University 60
Very early researchWithdrawnNCT06419166
What this trial is testing

An Exploratory Clinical Study of GC012F Injection for Refractory gMG

Who this might be right for
Refractory Generalized Myasthenia Gravis
Zhejiang University
Testing effectiveness (Phase 2)Ended earlyNCT00727194
What this trial is testing

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 14
Early research (Phase 1)Looking for participantsNCT06626919
What this trial is testing

Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

Who this might be right for
Muscular DiseasesNeuromuscular ManifestationsAutoimmune+4 more
Arcellx, Inc. 30
Not applicableNot Yet RecruitingNCT07226830
What this trial is testing

Quantification of Change in MG Disease Activity in Individuals With Generalized Myasthenia Gravis (gMG) After Administration of VYVGART® or VYVGART Hytrulo® Using BioDigit MG

Who this might be right for
Myasthenia Gravis Generalized
BioSensics 25
Large-scale testing (Phase 3)Study completedNCT04650854
What this trial is testing

Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis
UCB Biopharma SRL 165
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