Not applicableLooking for participantsNCT00359684What this trial is testingUse of Cysteamine in the Treatment of CystinosisWho this might be right forCystinosis National Human Genome Research Institute (NHGRI) 330
Testing effectiveness (Phase 2)Looking for participantsNCT06383533What this trial is testingDisitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct AdenocarcinomaWho this might be right forBile Duct Adenocarcinoma Non-ResectableHER2 Gene Mutation Zhejiang Cancer Hospital 28
Early research (Phase 1)Ended earlyNCT04835714What this trial is testingFind a Safe and Effective Dose of BI 1701963 Alone and in Combination With BI 3011441 in Patients With Advanced Cancer and a Certain Mutation (Kirsten Rat Sarcoma Viral Oncogene Homologue [KRAS])Who this might be right forSolid Tumors, KRAS Mutation Boehringer Ingelheim 8
Early research (Phase 1)Study completedNCT04330664What this trial is testingAdagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)Who this might be right forAdvanced CancerMetastatic CancerMalignant Neoplastic Disease Mirati Therapeutics Inc. 86
Not applicableStudy completedNCT04425200What this trial is testingPrevalence of HRR-related Genes Mutations and Prognosis in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients in Real World SettingWho this might be right forProstatic Neoplasms AstraZeneca 205
Post-approval studies (Phase 4)Study completedNCT02744664What this trial is testingCryotherapy Combine Icotinib for Advanced NSCLC TreatmentWho this might be right forLung Neoplasms Fuda Cancer Hospital, Guangzhou 60
Testing effectiveness (Phase 2)Study completedNCT00827684What this trial is testingTemsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS MutationsWho this might be right forMetastatic Colorectal Cancer Vejle Hospital 50
Large-scale testing (Phase 3)Study completedNCT02864251What this trial is testingNivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) TherapyWho this might be right forNon-Small-Cell Lung Carcinoma Bristol-Myers Squibb 367
Not applicableLooking for participantsNCT02432092What this trial is testingPediatric Cardiomyopathy Mutation AnalysisWho this might be right forCardiomyopathiesDilated CardiomyopathyHypertrophic Cardiomyopathy+3 more Indiana University 300
Large-scale testing (Phase 3)Active Not RecruitingNCT03839771What this trial is testingIvosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive ChemotherapyWho this might be right forAcute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2 Stichting Hemato-Oncologie voor Volwassenen Nederland 968
Early research (Phase 1)Study completedNCT03636204What this trial is testingA First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) MutationWho this might be right forHealthyFrontotemporal Dementia Alector Inc. 64
Testing effectiveness (Phase 2)Study completedNCT03812809What this trial is testingA Phase IIb Study of BPI-7711 Capsule in Non-small Cell Lung Cancer Patients With T790M Mutation PositiveWho this might be right forNSCLC Beta Pharma Shanghai 226
Not applicableNo Longer AvailableNCT04489433What this trial is testingCompassionate Use Program to Access Trametinib and Dabrafenib for Patients With BRAF Mutation-positive Metastatic MelanomaWho this might be right forMelanoma Novartis Pharmaceuticals
Early research (Phase 1)UnknownNCT05019534What this trial is testingTolerability and Safety of Vemurafenib, Cetuximab Combined With Camrelizumab for BRAF V600E-mutated /MSS Metastatic Colorectal CancerWho this might be right forBRAF V600E-mutated /MSS Metastatic Colorectal CancerVemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal Antibody West China Hospital 12
Not applicableUnknownNCT02738684What this trial is testingPredict Gefitinib' s Efficacy for Lung Cancer by Plasma Free Nucleic Acids EGFR Gene Mutation TestWho this might be right forLung Adenocarcinoma Southwest Hospital, China 100
Not applicableUnknownNCT05162508What this trial is testingImpact of COVID-19 SARS-CoV-2 Variability in ICU Hospitalized Patients With Severe DiseaseWho this might be right forSARS-CoV2 InfectionCOVID-19 Acute Respiratory Distress SyndromeMutation Assistance Publique - Hôpitaux de Paris 2,000
Early research (Phase 1)Ended earlyNCT04916236What this trial is testingCombination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant CancersWho this might be right forPancreatic CancerColorectal CancerNon-small Cell Lung Cancer+1 more The Netherlands Cancer Institute 24
Not applicableActive Not RecruitingNCT04285398What this trial is testingProspective Natural History Study of Retinitis PigmentosaWho this might be right forRetinitis Pigmentosa SparingVision 82
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05640726What this trial is testingThe First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard TherapyWho this might be right forRectal Cancer Fujian Cancer Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06456138What this trial is testingTrametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLCWho this might be right forKRAS Mutation-Related TumorsAdvanced Lung CancerRefractory Tumor Shanghai Chest Hospital 60