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Results for “Genetic Mutation”

3,468 trials

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Showing 20 of 3,468 results

Testing effectiveness (Phase 2)WithdrawnNCT05279859
What this trial is testing

Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia
Erasca, Inc.
Not applicableUnknownNCT05133388
What this trial is testing

The Prevelence of HBB c.93-21 G-A in β Thalassemia Patients

Who this might be right for
Beta-Thalassemia
Assiut University 150
Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Not applicableUnknownNCT02309866
What this trial is testing

Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases

Who this might be right for
Retinitis Pigmentosa
Hillel Yaffe Medical Center 100
Not applicableUnknownNCT05604573
What this trial is testing

DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Seoul National University Hospital 150
Not applicableUnknownNCT04909073
What this trial is testing

Observational Study of Afatinib 30 mg Daily

Who this might be right for
Non-Small Cell Lung CancerEpidermal Growth Factor Receptor Mutation
National University Hospital, Singapore 69
Not applicableEnded earlyNCT06140329
What this trial is testing

Natural History of Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Who this might be right for
Autosomal Dominant Optic AtrophyOptic Atrophy, Autosomal DominantOptic Atrophies, Hereditary+1 more
PYC Therapeutics 1
Testing effectiveness (Phase 2)WithdrawnNCT02355431
What this trial is testing

Itacitinib in Combination With Erlotinib in Non Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Activating Mutations

Who this might be right for
Solid Tumors and Hematologic MalignancyNSCLC (Non-small Cell Lung Carcinoma)
Incyte Corporation
Large-scale testing (Phase 3)UnknownNCT02387086
What this trial is testing

Gefitinib Combined With Thalidomide to Treat NSCLC

Who this might be right for
NSCLC
Bai Jun 380
Early research (Phase 1)Looking for participantsNCT06892054
What this trial is testing

Sotorasib Combined With First-line Chemotherapy for Advanced Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic Adenocarcinoma
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 15
Not applicableStudy completedNCT01150305
What this trial is testing

Epidemiology of Non-syndromic Dominant Deafness

Who this might be right for
Hearing Impairment
Assistance Publique - Hôpitaux de Paris 183
Not applicableStudy completedNCT06582537
What this trial is testing

LAMA2 Genetic Correction

Who this might be right for
MDC1A
Maastricht University 7
Not applicableStudy completedNCT02035046
What this trial is testing

Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter

Who this might be right for
Heterozygous Carriers of Gitelman Syndrome
Assistance Publique - Hôpitaux de Paris 250
Not applicableUnknownNCT03837054
What this trial is testing

Does Chemotherapy Train the Mutation of the Pig-A Gene? (PIGA)

Who this might be right for
Breast Cancer Female
Assistance Publique Hopitaux De Marseille 30
Testing effectiveness (Phase 2)UnknownNCT02407366
What this trial is testing

Icotinib With Concurrent Radiotherapy vs. Chemoradiotherapy in Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
People's Hospital of Guangxi Zhuang Autonomous Region 80
Not applicableLooking for participantsNCT05378204
What this trial is testing

Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer.

Who this might be right for
Breast Cancer
Institut Claudius Regaud 120
Not applicableStudy completedNCT04560270
What this trial is testing

CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer

Who this might be right for
Pancreatic CancerCirculating Tumor DNAKRAS Mutation-Related Tumors
Poitiers University Hospital 69
Testing effectiveness (Phase 2)UnknownNCT01131429
What this trial is testing

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Who this might be right for
Neoplasms, LungCarcinoma, Non-Small Cell LungDrug Therapy+1 more
Chinese PLA General Hospital 60
Not applicableLooking for participantsNCT06357845
What this trial is testing

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Who this might be right for
Somatic Mutation
Case Comprehensive Cancer Center 500
Testing effectiveness (Phase 2)Study completedNCT01854294
What this trial is testing

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Genervon Biopharmaceuticals, LLC 12
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