Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Genetic Mutations”

1,986 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 1,986 results

Not applicableStudy completedNCT01085227
What this trial is testing

Clinical, Molecular and by Neuroimaging of LRRK2 Mutations

Who this might be right for
Parkinson's Disease
Institut National de la Santé Et de la Recherche Médicale, France 50
Testing effectiveness (Phase 2)Study completedNCT04042558
What this trial is testing

A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

Who this might be right for
NSCLC Stage IIIBNSCLC Stage IVEGFR Gene Mutation+2 more
Centre Francois Baclesse 150
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07360743
What this trial is testing

Immunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 Levels

Who this might be right for
Non Small Cell Lung Cancer (Squamous or Non Squamous)
UNICANCER 275
Not applicableLooking for participantsNCT03564561
What this trial is testing

Natural History of Pompe Disease

Who this might be right for
Glycogen Storage Disease Type II, Adult
Assistance Publique - Hôpitaux de Paris 20
Not applicableEnrolling By InvitationNCT07307469
What this trial is testing

Compassionate Administration of ZVS101e Injection for Extended Treatment

Who this might be right for
Patients With Bietti Crystalline Corneoretinal Dystrophy (Carrying Biallelic CYP4V2 Mutations)
Chigenovo Co., Ltd 32
Testing effectiveness (Phase 2)UnknownNCT04692740
What this trial is testing

Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial)

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Michele Reni 20
Early research (Phase 1)Study completedNCT01969643
What this trial is testing

A Safety Study of SGN-LIV1A in Breast Cancer Patients

Who this might be right for
HER2 Positive Breast NeoplasmsHormone Receptor Positive Breast NeoplasmsTriple Negative Breast Neoplasms+1 more
Seagen Inc. 290
Not applicableUnknownNCT05411276
What this trial is testing

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

Who this might be right for
HER2 Mutant Non-small Cell Lung Cancer
Beijing Chest Hospital 15
Not applicableStudy completedNCT02285361
What this trial is testing

GIOTRIF rPMS in Korean Patients With NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 1,272
Testing effectiveness (Phase 2)Study completedNCT02676843
What this trial is testing

Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

Who this might be right for
Frontotemporal Lobar Degeneration (FTLD)Frontotemporal Dementia (FTD)Tauopathies
Columbia University 7
Early research (Phase 1)Looking for participantsNCT06659341
What this trial is testing

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Who this might be right for
Advanced Solid Tumors Harboring KRAS G12C Mutation
Bayer 104
Not applicableStudy completedNCT02380729
What this trial is testing

Mutation Exploration in Non-acquired, Genetic Disorders and Its Impact on Health Economy and Life Quality

Who this might be right for
Genetic Diseases
Charite University, Berlin, Germany 200
Not applicableStudy completedNCT00342251
What this trial is testing

Investigating Age-Related Macular Degeneration

Who this might be right for
Age-Related Macular Degeneration
National Eye Institute (NEI) 3,000
Large-scale testing (Phase 3)Study completedNCT03537651
What this trial is testing

Evaluate the Safety and Efficacy of Long-term Treatment With TEZ/IVA in CF Participants With an F508del CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 130
Not applicableStudy completedNCT04819490
What this trial is testing

A UK Multicentre, Health-Related Quality of Life Study for Children and Adolescents With XLH

Who this might be right for
X-Linked Hypophosphataemia
Kyowa Kirin Pharmaceutical Development Ltd 32
Early research (Phase 1)Study completedNCT00451074
What this trial is testing

Six Month Study of Gentamicin in Duchenne Muscular Dystrophy With Stop Codons

Who this might be right for
Duchenne Muscular Dystrophy
Nationwide Children's Hospital 12
Testing effectiveness (Phase 2)UnknownNCT02951637
What this trial is testing

Chemotherapy Plus Gefitinib for Advanced Lung Adenocarcinoma and Sensitive EGFR Mutations: a Randomized Controlled Trial

Who this might be right for
Lung Adenocarcinoma
Shanghai Chest Hospital 300
Not applicableLooking for participantsNCT07450612
What this trial is testing

Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection

Who this might be right for
Colorectal CancerAdenoma ColonAdenoma Colon Polyp+16 more
San Raffaele University 1,200
Not applicableStudy completedNCT06582537
What this trial is testing

LAMA2 Genetic Correction

Who this might be right for
MDC1A
Maastricht University 7
Testing effectiveness (Phase 2)Looking for participantsNCT06844383
What this trial is testing

Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate

Who this might be right for
Prostate Cancer (Adenocarcinoma)mCRPC (Metastatic Castration-resistant Prostate Cancer)
Prostate Cancer Clinical Trials Consortium 126
Load More Results