Not applicableStudy completedNCT00571025What this trial is testingRisk Evaluation and Education for Alzheimer's DiseaseWho this might be right forAlzheimer's Disease National Human Genome Research Institute (NHGRI) 301
Post-approval studies (Phase 4)Study completedNCT02087865What this trial is testingEffects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's DiseaseWho this might be right forGenetic Risk for Alzheimer's Disease The Cleveland Clinic 89
Large-scale testing (Phase 3)Looking for participantsNCT06647498What this trial is testingA Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationWho this might be right forAlzheimers DiseaseDementiaAlzheimers Disease, Familial Washington University School of Medicine 280
Early research (Phase 1)Ended earlyNCT06673069What this trial is testingHero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) and Pharmacodynamics (PD) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer's Disease (AD)Who this might be right forAlzheimer DiseaseDown Syndrome Ionis Pharmaceuticals, Inc. 1
Not applicableStudy completedNCT00089882What this trial is testingRisk Evaluation and Education for Alzheimer's Disease (REVEAL) IIWho this might be right forAlzheimer Disease National Institute on Aging (NIA) 360
Not applicableNot Yet RecruitingNCT06896201What this trial is testingComfortage - AD Prevention StrategiesWho this might be right forAlzheimer DiseaseSubjective Cognitive ImpairmentMild Cognitive Impairment Fondazione Policlinico Universitario Agostino Gemelli IRCCS 200
Large-scale testing (Phase 3)Looking for participantsNCT05552157What this trial is testingPotential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationWho this might be right forAlzheimers DiseaseDementiaAlzheimers Disease, Familial Washington University School of Medicine 280
Not applicableNot Yet RecruitingNCT05163067What this trial is testingCombined Aerobic Exercise and Cognitive Training in Seniors With Genetic Susceptibility for Alzheimer's DiseaseWho this might be right forAlzheimer Disease Xuanwu Hospital, Beijing 200
Not applicableLooking for participantsNCT06821568What this trial is testingHome-Based Brain Stimulation for Motoric Cognitive Risk SyndromeWho this might be right forAlzheimer Disease and Related DementiasCognitionMobility Disability Hebrew SeniorLife 128
Not applicableLooking for participantsNCT07516119What this trial is testingPredicting Pre-dementiaWho this might be right forMild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Alzheimer Disease (AD)+1 more Prevention Research Consortium Corp. 100
Not applicableStudy completedNCT06432192What this trial is testingA Prospective, Monocentric Clinical Study for the Validation of in Vitro Diagnostic Tests Developed by FiralisWho this might be right forGenetic Health Risks Firalis SA 1,474
Not applicableLooking for participantsNCT05795634What this trial is testingCognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's DiseaseWho this might be right forMild Cognitive ImpairmentAlzheimer Disease Johns Hopkins University 240
Not applicableStudy completedNCT01434667What this trial is testingRisk Evaluation and Education for Alzheimer's Disease (REVEAL) IVWho this might be right forMild Cognitive Impairment Brigham and Women's Hospital 146
Not applicableStudy completedNCT00462917What this trial is testingREVEAL III: Risk Evaluation and Education for Alzheimer's DiseaseWho this might be right forAlzheimer Disease Brigham and Women's Hospital 290
Large-scale testing (Phase 3)Ended earlyNCT06424236What this trial is testingDominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic MutationWho this might be right forAlzheimers DiseaseDementiaAlzheimers Disease, Familial Washington University School of Medicine 73
Large-scale testing (Phase 3)Study completedNCT04623242What this trial is testingDominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.Who this might be right forAlzheimers DiseaseDementiaAlzheimers Disease, Familial Washington University School of Medicine 194
Not applicableLooking for participantsNCT00064870What this trial is testingAlzheimer's Disease Genetics StudyWho this might be right forAlzheimer DiseaseLate Onset Alzheimer DiseaseDementia Indiana University 10,000
Not applicableActive Not RecruitingNCT04748861What this trial is testingCYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)Who this might be right forHigh Intensity ExerciseNormal CognitionExercise Intervention The Cleveland Clinic 150
Not applicableWithdrawnNCT03641768What this trial is testingRisk Prediction for Alzheimer Dementia With Brain Imaging and GeneticsWho this might be right forAlzheimer DementiaPosttraumatic Stress DisorderTraumatic Brain Injury Duke University
Large-scale testing (Phase 3)Active Not RecruitingNCT01760005What this trial is testingDominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001Who this might be right forAlzheimers DiseaseDementiaAlzheimers Disease, Familial Washington University School of Medicine 490