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Results for “Genetically”

273 trials

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Showing 20 of 273 results

Not applicableStudy completedNCT01719367
What this trial is testing

Genetically Determined Response to Atenolol in Patients With Persistent Atrial Fibrillation

Who this might be right for
Atrial Fibrillation
Vanderbilt University Medical Center 38
Testing effectiveness (Phase 2)Ended earlyNCT02976038
What this trial is testing

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 28
Early research (Phase 1)Study completedNCT00408525
What this trial is testing

Donepezil and Brain Activity Patterns in Those at Risk For Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Vanderbilt University 41
Early research (Phase 1)Active Not RecruitingNCT04526834
What this trial is testing

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Who this might be right for
Anaplastic Large Cell LymphomaPeripheral T Cell LymphomaExtranodal NK/T-cell Lymphoma+2 more
Tessa Therapeutics 21
Large-scale testing (Phase 3)Study completedNCT03505099
What this trial is testing

Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2

Who this might be right for
Spinal Muscular Atrophy
Novartis Gene Therapies 30
Early research (Phase 1)Looking for participantsNCT05432635
What this trial is testing

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

Who this might be right for
B-Cell Non-Hodgkin LymphomaDiffuse Large B-Cell LymphomaMantle Cell Lymphoma+5 more
City of Hope Medical Center 15
Not applicableActive Not RecruitingNCT02354079
What this trial is testing

HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism

Who this might be right for
Hypobetalipoproteinemia
Nantes University Hospital 435
Early research (Phase 1)Study completedNCT00621452
What this trial is testing

Genetically Engineered Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Indolent B-Cell Non-Hodgkin Lymphoma

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaExtranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell Lymphoma+8 more
Fred Hutchinson Cancer Center 12
Testing effectiveness (Phase 2)UnknownNCT03276455
What this trial is testing

Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically Modified

Who this might be right for
Beta Thalassemia Major
Nanfang Hospital, Southern Medical University 10
Testing effectiveness (Phase 2)Study completedNCT01643330
What this trial is testing

Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure

Who this might be right for
Ischemic CardiomyopathyNon-ischemic CardiomyopathyHeart Failure+1 more
Celladon Corporation 250
Not applicableWithdrawnNCT01769911
What this trial is testing

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Who this might be right for
Adult Nasal Type Extranodal NK/T-cell LymphomaAIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell Lymphoma+42 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT04639245
What this trial is testing

Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Solid Neoplasm+3 more
Fred Hutchinson Cancer Center 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT02068794
What this trial is testing

MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Who this might be right for
Fallopian Tube Clear Cell AdenocarcinomaFallopian Tube Endometrioid AdenocarcinomaFallopian Tube Mucinous Adenocarcinoma+15 more
Mayo Clinic 34
Testing effectiveness (Phase 2)Active Not RecruitingNCT01318317
What this trial is testing

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

Who this might be right for
Recurrent Grade 1 Follicular LymphomaRecurrent Grade 2 Follicular LymphomaRecurrent Grade 3 Follicular Lymphoma+2 more
City of Hope Medical Center 8
Not applicableNot Yet RecruitingNCT06673004
What this trial is testing

Ovarian Tissue Allo-transplantation

Who this might be right for
Ovarian FailureOvarian InsufficiencyMenopause Ovarian Failure+3 more
Rebecca Flyckt 10
Testing effectiveness (Phase 2)Ended earlyNCT02346422
What this trial is testing

High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure

Who this might be right for
Ischemic CardiomyopathyNon-ischemic CardiomyopathyHeart Failure+1 more
Celladon Corporation 9
Testing effectiveness (Phase 2)Temporarily pausedNCT04846036
What this trial is testing

The KHENERGYC Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMELAS+1 more
Khondrion BV 24
Early research (Phase 1)Study completedNCT00004216
What this trial is testing

VNP20009 in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Therapy

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Vion Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT03138096
What this trial is testing

Safety and Protective Efficacy of Pb(PfCS@UIS4)

Who this might be right for
Malaria,FalciparumPlasmodium FalciparumPlasmodium Berghei+1 more
Radboud University Medical Center 24
Not applicableLooking for participantsNCT06264570
What this trial is testing

Evaluation of a Genetically Determined Personalized Approach in Prescribing Biologically Active Substances in Patients With Elevated Blood Homocysteine Levels.

Who this might be right for
Hyperhomocysteinemia
S.LAB (SOLOWAYS) 111
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