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Results for “Genomic Instability”

67 trials

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Showing 20 of 67 results

Not applicableStudy completedNCT06238193
What this trial is testing

Molecular Characteristics of Early-onset Compared With Late-onset Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability
The First Affiliated Hospital with Nanjing Medical University 11,344
Early research (Phase 1)Study completedNCT03538028
What this trial is testing

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Who this might be right for
Cervical CancerMicrosatellite Instability (MSI)-High Endometrial CancerGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+14 more
Incyte Biosciences International Sàrl 22
Testing effectiveness (Phase 2)Study completedNCT03519412
What this trial is testing

Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status

Who this might be right for
Colorectal NeoplasmsMicrosatellite Instability
IFOM ETS - The AIRC Institute of Molecular Oncology 107
Not applicableUnknownNCT03561350
What this trial is testing

Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing

Who this might be right for
Colorectal Neoplasms
Shanghai Minimally Invasive Surgery Center 60
Not applicableUnknownNCT00232960
What this trial is testing

Postoperative Radiotherapy According to Molecular Analysis of Surgical Margins of Oral and Oropharyngeal SCC

Who this might be right for
Oral CancerOropharynx Cancer
Gustave Roussy, Cancer Campus, Grand Paris 310
Testing effectiveness (Phase 2)Active Not RecruitingNCT02314481
What this trial is testing

Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity

Who this might be right for
Non-small Cell Lung Cancer
University College, London 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT03228667
What this trial is testing

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerUrothelial Carcinoma+10 more
ImmunityBio, Inc. 40
Not applicableEnded earlyNCT04106167
What this trial is testing

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Who this might be right for
Advanced Solid TumorLymphomaGastric Cancer+15 more
Fate Therapeutics 20
Testing effectiveness (Phase 2)Study completedNCT03436563
What this trial is testing

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Who this might be right for
Colon AdenocarcinomaHigh-Frequency Microsatellite InstabilityMetastatic Malignant Solid Neoplasm+8 more
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06646445
What this trial is testing

Neoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.

Who this might be right for
Colon Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 60
Not applicableUnknownNCT04122092
What this trial is testing

Evaluation of Ultrasensitive Chromosomal Aneuploidy Detection for Detecting Minimal Residual Disease in Multiple Myeloma

Who this might be right for
Multiple Myeloma
Shanghai Changzheng Hospital 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT03607890
What this trial is testing

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Who this might be right for
Refractory MSI - H Solid Tumors Prior of PD-(L) 1 TherapyMSI-H Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Not applicableUnknownNCT00141466
What this trial is testing

Implementation of a New Strategy to Identify HNPCC Patients

Who this might be right for
Colorectal NeoplasmsHereditary Nonpolyposis Colorectal Cancer
Radboud University Medical Center 360
Testing effectiveness (Phase 2)Active Not RecruitingNCT04817826
What this trial is testing

TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.

Who this might be right for
Gastric CancerMicrosatellite Instability
Gruppo Oncologico del Nord-Ovest 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT04006262
What this trial is testing

Pre-operative Nivolumab and Ipilimumab, Followed by Post-operative Nivolumab, for MSI/dMMR Oeso-gastric Adenocarcinoma.

Who this might be right for
Localized Oesogastric AdenocarcimonaMSI and or dMMR
GERCOR - Multidisciplinary Oncology Cooperative Group 32
Early research (Phase 1)Looking for participantsNCT06004245
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsColorectal Cancer
Vividion Therapeutics, Inc. 280
Not applicableUnknownNCT05845554
What this trial is testing

Application of Chromosomal Instability in Early Diagnosis of Biliary Tract Carcinoma

Who this might be right for
Biliary Tract Carcinoma
Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University 300
Not applicableLooking for participantsNCT05058937
What this trial is testing

Examine the Clinical Value of Comprehensive Genomic Profiling Performed by Belgian NGS Laboratories: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Centre

Who this might be right for
Solid TumorMetastatic Cancer
The Belgian Society of Medical Oncology 936
Not applicableActive Not RecruitingNCT05511688
What this trial is testing

National Cohort of Colorectal Cancers With Microsatellite Instability

Who this might be right for
Colorectal CancerMicrosatellite Instability
Federation Francophone de Cancerologie Digestive 637
Not applicableUnknownNCT03744962
What this trial is testing

MSI in Circulatory DNA of Endometrial Cancer

Who this might be right for
Microsatellite InstabilityLynch SyndromeEndometrial Cancer+1 more
Lei Li 100
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