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Results for “Glioblastoma, IDH-mutant”

33 trials

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Showing 20 of 33 results

Not applicableLooking for participantsNCT07832734
What this trial is testing

Metabolomics and Transcriptomics of Low- and High-Grade Gliomas

Who this might be right for
IDH Wildtype GlioblastomaIDH Mutant Lower-Grade Gliomas
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 220
Not applicableNot Yet RecruitingNCT06368934
What this trial is testing

Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant Glioblastoma

Who this might be right for
GliomaGlioblastoma
Huashan Hospital 326
Early research (Phase 1)Study completedNCT04908176
What this trial is testing

A Drug-drug Interaction Study of Avapritinib and Midazolam

Who this might be right for
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more
Blueprint Medicines Corporation 10
Post-approval studies (Phase 4)Study completedNCT06625047
What this trial is testing

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Who this might be right for
Astrocytoma, IDH-MutantGlioblastomaGlioma+1 more
Mayo Clinic 30
Early research (Phase 1)Looking for participantsNCT05879367
What this trial is testing

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

Who this might be right for
Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme+4 more
Orbus Therapeutics, Inc. 66
Early research (Phase 1)Looking for participantsNCT07223034
What this trial is testing

177Lu-PSMA-617 in People With Gliomas

Who this might be right for
GliomaDiffuse Astrocytoma, IDH-Wildtype (Grade 2-4)Glioblastoma, IDH-wildtype+3 more
Memorial Sloan Kettering Cancer Center 20
Early research (Phase 1)Enrolling By InvitationNCT06896110
What this trial is testing

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

Who this might be right for
Glioblastoma (GBM)Diffuse Midline Glioma (DMG)Astrocytoma, IDH-Mutant, Grade 4+2 more
Andrew P. Groves 34
Not applicableStudy completedNCT05375318
What this trial is testing

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels

Who this might be right for
Astrocytoma, Grade IVGlioblastomaGlioblastoma Multiforme+5 more
Juan M Garcia-Gomez 50
Not applicableStudy completedNCT05229198
What this trial is testing

ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas

Who this might be right for
Astrocytoma, Grade IV
Juan M Garcia-Gomez 300
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Looking for participantsNCT07468136
What this trial is testing

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Who this might be right for
Anaplastic OligodendrogliomaAstrocytoma, IDH-Mutant, Grade 3Astrocytoma, IDH-Mutant, Grade 4+3 more
Mayo Clinic 33
Large-scale testing (Phase 3)Looking for participantsNCT05303519
What this trial is testing

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

Who this might be right for
GliomaAstrocytoma, Grade IVIDH1-mutant Glioma+5 more
Nuvation Bio Inc. 365
Testing effectiveness (Phase 2)Looking for participantsNCT07831369
What this trial is testing

VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent Glioma

Who this might be right for
GlioblastomaAstrocytoma, IDH-Mutant, Grade 4
Inova Health Care Services 52
Testing effectiveness (Phase 2)Looking for participantsNCT07708961
What this trial is testing

Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma

Who this might be right for
Glioblastoma, IDH-Wildtype
Mayo Clinic 60
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115
What this trial is testing

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT03718767
What this trial is testing

Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype

Who this might be right for
GliomaGlioblastomaHigh Grade Glioma+2 more
National Cancer Institute (NCI) 62
Early research (Phase 1)Looking for participantsNCT06860594
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Adult Diffuse Midline Glioma, H3 K27-Mutant+4 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05565521
What this trial is testing

UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly

Who this might be right for
Glioblastoma Multiforme, AdultGlioblastoma, IDH-mutant
Sunnybrook Health Sciences Centre 55
Testing effectiveness (Phase 2)Ended earlyNCT05267106
What this trial is testing

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations

Who this might be right for
GlioblastomaAdult-type Diffuse Gliomas
Incyte Corporation 83
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