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Results for “Glioblastoma Multiforme (GBM) WHO Grade IV”

124 trials

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Showing 20 of 124 results

Testing effectiveness (Phase 2)WithdrawnNCT05218408
What this trial is testing

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type

Who this might be right for
Astrocytoma, Grade IVGlioblastomaGiant Cell Glioblastoma+1 more
Celularity Incorporated
Very early researchLooking for participantsNCT04135807
What this trial is testing

Implantable Microdevice In Primary Brain Tumors

Who this might be right for
Grade II GliomaGrade III GliomaGrade IV Glioma+5 more
Oliver Jonas 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195139
What this trial is testing

Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM

Who this might be right for
Glioblastoma Multiforme
University of Sydney 103
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Testing effectiveness (Phase 2)Study completedNCT00752323
What this trial is testing

Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma

Who this might be right for
Brain and Central Nervous System Tumors
Andrew Sloan, MD 73
Testing effectiveness (Phase 2)Study completedNCT01866449
What this trial is testing

Prospective Phase 2 Trial of Cabazitaxel in Patients With Temozolomide Refractory Glioblastoma Multiforme

Who this might be right for
Glioblastoma Multiforme (GBM) WHO Grade IV
University of Ulm 24
Early research (Phase 1)Study completedNCT02903069
What this trial is testing

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Who this might be right for
GlioblastomaMalignant Glioma
Celgene 66
Not applicableActive Not RecruitingNCT03251027
What this trial is testing

Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma

Who this might be right for
GlioblastomaWHO Grade II GliomaWHO Grade III Glioma
Sidney Kimmel Cancer Center at Thomas Jefferson University 100
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Testing effectiveness (Phase 2)Ended earlyNCT03927222
What this trial is testing

Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma

Who this might be right for
Glioblastoma
Mustafa Khasraw, MBChB, MD, FRCP, FRACP 6
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Very early researchStudy completedNCT01091792
What this trial is testing

Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM)

Who this might be right for
Glioblastoma Multiforme
Dartmouth-Hitchcock Medical Center 13
Early research (Phase 1)Study completedNCT01470794
What this trial is testing

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaAnaplastic Oligodendroglioma+1 more
Tocagen Inc. 58
Testing effectiveness (Phase 2)Looking for participantsNCT05736406
What this trial is testing

A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma

Who this might be right for
Primary Glioblastoma
Hemerion Therapeutics 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03405792
What this trial is testing

Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)

Who this might be right for
GlioblastomaGlioblastoma, WHO Grade IV
University of Florida 40
Early research (Phase 1)Study completedNCT02270034
What this trial is testing

Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma Multiforme (Grade IV) of Cerebellum
Grupo Español de Investigación en Neurooncología 38
Early research (Phase 1)Study completedNCT03072134
What this trial is testing

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

Who this might be right for
GliomaAnaplastic AstrocytomaAnaplastic Oligodendroglioma+5 more
Northwestern University 12
Not applicableWithdrawnNCT03956706
What this trial is testing

Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas

Who this might be right for
GlioblastomaAstrocytoma, Grade IIIAstrocytoma, Grade IV+1 more
Northwell Health
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Very early researchActive Not RecruitingNCT06333899
What this trial is testing

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 15
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