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Results for “Gorlin Syndrome”

43 trials

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Showing 20 of 43 results

Not applicableEnrolling By InvitationNCT06330324
What this trial is testing

Reproductive Options in Inherited Skin Diseases

Who this might be right for
IchthyosisPalmoplantar KeratosesEpidermolysis Bullosa+7 more
Maastricht University Medical Center 650
Testing effectiveness (Phase 2)Study completedNCT01556009
What this trial is testing

Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas

Who this might be right for
Basal Cell Nevus SyndromeGorlin's Syndrome
UCSF Benioff Children's Hospital Oakland 24
Testing effectiveness (Phase 2)Study completedNCT00961896
What this trial is testing

A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients

Who this might be right for
Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients
Novartis Pharmaceuticals 18
Not applicableLooking for participantsNCT05463757
What this trial is testing

Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study

Who this might be right for
Basal Cell CarcinomaLocally Advanced Basal Cell CarcinomaMetastatic Basal Cell Carcinoma+8 more
Maastricht University Medical Center 80
Testing effectiveness (Phase 2)Ended earlyNCT04155190
What this trial is testing

Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Who this might be right for
Recurrent Basal Cell Carcinoma
Sol-Gel Technologies, Ltd. 47
Large-scale testing (Phase 3)Active Not RecruitingNCT06050122
What this trial is testing

Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome

Who this might be right for
Gorlin Syndrome
Sol-Gel Technologies, Ltd. 140
Early research (Phase 1)Study completedNCT03467789
What this trial is testing

Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma

Who this might be right for
Basal Cell CarcinomaBasal Cell Nevus Syndrome
Case Comprehensive Cancer Center 37
Testing effectiveness (Phase 2)Study completedNCT00023621
What this trial is testing

Celecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome

Who this might be right for
Non-melanomatous Skin Cancer
University of California, San Francisco 60
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Large-scale testing (Phase 3)WithdrawnNCT03070691
What this trial is testing

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Who this might be right for
Basal Cell Carcinoma
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT00783965
What this trial is testing

Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back

Who this might be right for
Skin Carcinoma
UCSF Benioff Children's Hospital Oakland 34
Early research (Phase 1)Looking for participantsNCT06623201
What this trial is testing

Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas

Who this might be right for
Basal Cell Carcinoma (BCC)
Nathalie Zeitouni 20
Testing effectiveness (Phase 2)Temporarily pausedNCT03208296
What this trial is testing

Study of ASN-002 to Treat Basal Cell Carcinomas (BCCs) in Individuals With Basal Cell Nevus Syndrome (BCNS)

Who this might be right for
Basal Cell Carcinoma in Basal Cell Nevus Syndrome
Ascend Biopharmaceuticals Ltd 24
Testing effectiveness (Phase 2)Study completedNCT01350115
What this trial is testing

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Who this might be right for
Basal Cell CarcinomaGorlin SyndromeNevoid Basal Cell Carcinoma Syndrome
Novartis Pharmaceuticals 10
Testing effectiveness (Phase 2)Ended earlyNCT02303041
What this trial is testing

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Who this might be right for
Carcinoma, Basal CellRecurrent Skin CancerSkin Neoplasms+1 more
Anne Chang 10
Not applicableUnknownNCT05898347
What this trial is testing

Nevoid Basal Cell Carcinomas in Gorlin Syndrome

Who this might be right for
Basal Cell CarcinomaGorlin Syndrome
Oslo University Hospital 10
Testing effectiveness (Phase 2)Study completedNCT00957229
What this trial is testing

To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)

Who this might be right for
Basal Cell Nevus SyndromeGorlin Syndrome
UCSF Benioff Children's Hospital Oakland 41
Early research (Phase 1)Study completedNCT02639117
What this trial is testing

Photodynamic Therapy and Vismodegib for Multiple Basal Cell Carcinomas

Who this might be right for
Basal Cell Carcinoma
University of Arizona 4
Not applicableStudy completedNCT00555633
What this trial is testing

Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients

Who this might be right for
Skin CancerXeroderma PigmentosumBasal Cell Nevus Syndrome
Medical University of Graz 13
Not applicableStudy completedNCT01014819
What this trial is testing

A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions

Who this might be right for
Basal Cell Carcinoma
UCSF Benioff Children's Hospital Oakland 30
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