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Results for “Grade 3 or 4 Astrocytoma”

9 trials

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Showing 9 of 9 results

Early research (Phase 1)Ended earlyNCT04782609
What this trial is testing

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma

Who this might be right for
Recurrent Glioblastoma Multiforme (GBM)Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype AstrocytomaGrade 3 or 4 Astrocytoma+1 more
Samus Therapeutics, Inc. 7
Early research (Phase 1)Looking for participantsNCT06815029
What this trial is testing

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma
City of Hope Medical Center 27
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Ended earlyNCT02255461
What this trial is testing

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Who this might be right for
Childhood Choroid Plexus TumorChildhood EpendymoblastomaChildhood Grade III Meningioma+16 more
Pediatric Brain Tumor Consortium 35
Early research (Phase 1)Study completedNCT00006368
What this trial is testing

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerGastrointestinal Carcinoid Tumor+5 more
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)Looking for participantsNCT05084430
What this trial is testing

Study of Pembrolizumab and M032 (NSC 733972)

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaGliosarcoma
University of Alabama at Birmingham 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07468136
What this trial is testing

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Who this might be right for
Anaplastic OligodendrogliomaAstrocytoma, IDH-Mutant, Grade 3Astrocytoma, IDH-Mutant, Grade 4+3 more
Mayo Clinic 33
Early research (Phase 1)Looking for participantsNCT06860594
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Adult Diffuse Midline Glioma, H3 K27-Mutant+4 more
National Cancer Institute (NCI) 30