Not applicableLooking for participantsNCT05644080What this trial is testing68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 GliomaWho this might be right forHigh Grade Glioma St. Olavs Hospital 10
Early research (Phase 1)Not Yet RecruitingNCT07541781What this trial is testingSitagliptin in Recurrent/Progressive Grade 4 GliomaWho this might be right forGliomaGlioblastomaRecurrent Glioma+2 more Kailin Yang, MD, PhD 45
Early research (Phase 1)Ended earlyNCT04782609What this trial is testingStudy of Icapamespib (PU-AD) in Patients With Recurrent Malignant GliomaWho this might be right forRecurrent Glioblastoma Multiforme (GBM)Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype AstrocytomaGrade 3 or 4 Astrocytoma+1 more Samus Therapeutics, Inc. 7
Early research (Phase 1)Looking for participantsNCT07544992What this trial is testingLocoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade GliomasWho this might be right forRecurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype City of Hope Medical Center 24
Testing effectiveness (Phase 2)Study completedNCT03778294What this trial is testing18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation TherapyWho this might be right forGlioblastomaMalignant Glioma Mayo Clinic 43
Testing effectiveness (Phase 2)Study completedNCT02330562What this trial is testingStage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and BevacizumabWho this might be right forMalignant GliomaGlioblastoma Celgene 121
Testing effectiveness (Phase 2)Looking for participantsNCT06161974What this trial is testingStudy of Olutasidenib and Temozolomide in HGGWho this might be right forHigh Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more Rigel Pharmaceuticals 60
Testing effectiveness (Phase 2)Looking for participantsNCT06444412What this trial is testingAn Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With GliomaWho this might be right forWHO Grade 3 GliomaWHO Grade 4 Glioma Mayo Clinic 25
Early research (Phase 1)Study completedNCT02903069What this trial is testingStudy of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain CancerWho this might be right forGlioblastomaMalignant Glioma Celgene 66
Early research (Phase 1)Looking for participantsNCT06815029What this trial is testingIntracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant AstrocytomaWho this might be right forRecurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma City of Hope Medical Center 27
Not applicableStudy completedNCT03471546What this trial is testingEarly Palliative Care Intervention in Malignant GliomaWho this might be right forMalignant Glioma Duke University 12
Large-scale testing (Phase 3)Looking for participantsNCT06160492What this trial is testingPhase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)Who this might be right for5-aminolevulinic AcidFluorescence-guided Resection Lee's Pharmaceutical Limited 144
Early research (Phase 1)Study completedNCT02529072What this trial is testingNivolumab With DC Vaccines for Recurrent Brain TumorsWho this might be right forMalignant GliomaAstrocytomaGlioblastoma Gary Archer Ph.D. 6
Not applicableLooking for participantsNCT06623565What this trial is testingExtensive Resection of Malignant Brain Tumors Using Advanced Imaging TechniquesWho this might be right forGlioblastomaAstrocytoma, IDH-Mutant, Grade 4 Amsterdam UMC, location VUmc 30
Testing effectiveness (Phase 2)WithdrawnNCT03973879What this trial is testingCombination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant GliomaWho this might be right forMalignant Glioma Darell Bigner
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849What this trial is testingStudy of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)Who this might be right forHigh Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more Nationwide Children's Hospital 79
Early research (Phase 1)Study completedNCT03434262What this trial is testingSJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsWho this might be right forAnaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more St. Jude Children's Research Hospital 68
Early research (Phase 1)Study completedNCT00612651What this trial is testingPH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant GliomasWho this might be right forGliosarcomaGlioblastomaAnaplastic Astrocytoma Duke University 37
Very early researchActive Not RecruitingNCT05182905What this trial is testingAZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma PatientsWho this might be right forGlioblastomaGliomaGlioblastoma Multiforme+1 more Nader Sanai 97
Early research (Phase 1)Ended earlyNCT00272870What this trial is testingTreatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to ChemotherapyWho this might be right forGlioblastoma Multiforme (WHO Grade IV)Anaplastic Astrocytoma (WHO Grade III) Children's Hospital Medical Center, Cincinnati 1