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Results for “Grade 4 Malignant Glioma”

80 trials

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Showing 20 of 80 results

Testing effectiveness (Phase 2)Looking for participantsNCT06630260
What this trial is testing

5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours

Who this might be right for
Glioblastoma Multiforme (GBM)Glioblastoma Multiform (Grade IV Astrocytoma)Diffuse Hemispheric Glioma, H3 G34-Mutant+1 more
Institute of Cancer Research, United Kingdom 182
Testing effectiveness (Phase 2)Ended earlyNCT01966809
What this trial is testing

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas

Who this might be right for
Brain Tumor, Recurrent
Harry T Whelan, MD 1
Early research (Phase 1)Ended earlyNCT02664363
What this trial is testing

EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma

Who this might be right for
GlioblastomaGliosarcoma
Daniel Landi 3
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Not applicableNot Yet RecruitingNCT07366892
What this trial is testing

Leica Microsystems Sponsored PMCF Study to Collect and Confirm Clinical Data on the Performance of the GLOW400 Device When Used in Accordance With Its Intended Use

Who this might be right for
Suspected Grade III and IV Gliomas Requiring Surgical InterventionNeurosurgical ProcedureGlioma+1 more
Leica Microsystems (Schweiz) AG 37
Very early researchNot Yet RecruitingNCT07784985
What this trial is testing

NST-628 in Recurrent Grade 4 Glioma

Who this might be right for
Glioma, Recurrent High GradeGrade 4 Malignant Glioma
Nader Sanai 12
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Early research (Phase 1)Study completedNCT01144247
What this trial is testing

Cellular Immunotherapy Study for Brain Cancer

Who this might be right for
GliomasAnaplastic AstrocytomaAnaplastic Oligodendroglioma+3 more
Jonsson Comprehensive Cancer Center 10
Not applicableNot Yet RecruitingNCT07590726
What this trial is testing

PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors

Who this might be right for
Brain Injuries, AcuteBrain Tumor AdultBrain (Nervous System) Cancers+4 more
Rigshospitalet, Denmark 160
Early research (Phase 1)Study completedNCT01156584
What this trial is testing

A Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma

Who this might be right for
GlioblastomaAnaplastic AstrocytomaAnaplastic Oligodendroglioma+1 more
Tocagen Inc. 54
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Very early researchActive Not RecruitingNCT05182905
What this trial is testing

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Who this might be right for
GlioblastomaGliomaGlioblastoma Multiforme+1 more
Nader Sanai 97
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Very early researchLooking for participantsNCT06333899
What this trial is testing

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 15
Large-scale testing (Phase 3)UnknownNCT05479136
What this trial is testing

18F-Fluciclovine PET Imaging for Detecting High Grade Glioma Recurrence After Radiochemotherapy

Who this might be right for
Grade III or Grade IV Glioma
Nicole Hill 30
Early research (Phase 1)Study completedNCT03072134
What this trial is testing

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

Who this might be right for
GliomaAnaplastic AstrocytomaAnaplastic Oligodendroglioma+5 more
Northwestern University 12
Testing effectiveness (Phase 2)UnknownNCT01903330
What this trial is testing

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

Who this might be right for
GlioblastomaGliosarcoma
Epitopoietic Research Corporation 84
Testing effectiveness (Phase 2)Active Not RecruitingNCT06413706
What this trial is testing

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

Who this might be right for
Glioma
Eli Lilly and Company 45
Early research (Phase 1)Looking for participantsNCT06815029
What this trial is testing

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma
City of Hope Medical Center 27
Early research (Phase 1)Looking for participantsNCT06482905
What this trial is testing

Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.

Who this might be right for
High-grade GliomaWHO Grade Ⅳ Glioma
Tcelltech Inc. 52
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