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Results for “Grade 4 Malignant Glioma”

80 trials

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Showing 20 of 80 results

Testing effectiveness (Phase 2)Looking for participantsNCT01906385
What this trial is testing

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Who this might be right for
Glioma
Cerenome 55
Not applicableNot Yet RecruitingNCT07590726
What this trial is testing

PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors

Who this might be right for
Brain Injuries, AcuteBrain Tumor AdultBrain (Nervous System) Cancers+4 more
Rigshospitalet, Denmark 160
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Early research (Phase 1)Study completedNCT02529072
What this trial is testing

Nivolumab With DC Vaccines for Recurrent Brain Tumors

Who this might be right for
Malignant GliomaAstrocytomaGlioblastoma
Gary Archer Ph.D. 6
Not applicableStudy completedNCT03471546
What this trial is testing

Early Palliative Care Intervention in Malignant Glioma

Who this might be right for
Malignant Glioma
Duke University 12
Early research (Phase 1)Study completedNCT01172964
What this trial is testing

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Who this might be right for
Adult Anaplastic AstrocytomaRecurrent Grade III GliomaRecurrent Grade IV Glioma+9 more
City of Hope Medical Center 15
Early research (Phase 1)Looking for participantsNCT06815029
What this trial is testing

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma
City of Hope Medical Center 27
Testing effectiveness (Phase 2)Looking for participantsNCT07416188
What this trial is testing

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

Who this might be right for
Recurrent GlioblastomaGlioblastoma IDH (Isocitrate Dehydrogenase) WildtypeRelapsed Cancer+12 more
National Institute of Neurological Disorders and Stroke (NINDS) 40
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Testing effectiveness (Phase 2)Study completedNCT00071539
What this trial is testing

Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors

Who this might be right for
Recurrent Glioblastoma Multiforme
Teva Branded Pharmaceutical Products R&D, Inc. 56
Not applicableLooking for participantsNCT06118723
What this trial is testing

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

Who this might be right for
GlioblastomaHigh-grade GliomaGlioblastoma, IDH-wildtype+9 more
Jasper Gerritsen 784
Testing effectiveness (Phase 2)Study completedNCT00104091
What this trial is testing

Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors

Who this might be right for
Glioblastoma Multiforme
Teva Branded Pharmaceutical Products R&D, Inc. 56
Early research (Phase 1)Enrolling By InvitationNCT06896110
What this trial is testing

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

Who this might be right for
Glioblastoma (GBM)Diffuse Midline Glioma (DMG)Astrocytoma, IDH-Mutant, Grade 4+2 more
Andrew P. Groves 34
Early research (Phase 1)Ended earlyNCT00272870
What this trial is testing

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

Who this might be right for
Glioblastoma Multiforme (WHO Grade IV)Anaplastic Astrocytoma (WHO Grade III)
Children's Hospital Medical Center, Cincinnati 1
Early research (Phase 1)Study completedNCT01985256
What this trial is testing

Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaAnaplastic Oligodendroglioma+1 more
Tocagen Inc. 17
Testing effectiveness (Phase 2)WithdrawnNCT03973879
What this trial is testing

Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Darell Bigner
Testing effectiveness (Phase 2)Looking for participantsNCT06630260
What this trial is testing

5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours

Who this might be right for
Glioblastoma Multiforme (GBM)Glioblastoma Multiform (Grade IV Astrocytoma)Diffuse Hemispheric Glioma, H3 G34-Mutant+1 more
Institute of Cancer Research, United Kingdom 182
Not applicableWithdrawnNCT03956706
What this trial is testing

Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas

Who this might be right for
GlioblastomaAstrocytoma, Grade IIIAstrocytoma, Grade IV+1 more
Northwell Health
Early research (Phase 1)Active Not RecruitingNCT06632236
What this trial is testing

5G-EMERALD: Amivantamab in Malignant Brain Tumours

Who this might be right for
Malignant Primary GliomasGlioblastoma Multiform (Grade IV Astrocytoma)Diffuse Hemispheric Glioma, H3 G34-Mutant+1 more
Institute of Cancer Research, United Kingdom 12
Testing effectiveness (Phase 2)Study completedNCT02986178
What this trial is testing

Lerapolturev in Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Istari Oncology, Inc. 121
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