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Results for “Grade 4 Malignant Glioma of Brain (Disorder)”

29 trials

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Showing 20 of 29 results

Early research (Phase 1)Not Yet RecruitingNCT07541781
What this trial is testing

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

Who this might be right for
GliomaGlioblastomaRecurrent Glioma+2 more
Kailin Yang, MD, PhD 45
Testing effectiveness (Phase 2)Study completedNCT02330562
What this trial is testing

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

Who this might be right for
Malignant GliomaGlioblastoma
Celgene 121
Early research (Phase 1)Study completedNCT02903069
What this trial is testing

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Who this might be right for
GlioblastomaMalignant Glioma
Celgene 66
Testing effectiveness (Phase 2)WithdrawnNCT03973879
What this trial is testing

Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Darell Bigner
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Study completedNCT00612651
What this trial is testing

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

Who this might be right for
GliosarcomaGlioblastomaAnaplastic Astrocytoma
Duke University 37
Not applicableNot Yet RecruitingNCT07590726
What this trial is testing

PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors

Who this might be right for
Brain Injuries, AcuteBrain Tumor AdultBrain (Nervous System) Cancers+4 more
Rigshospitalet, Denmark 160
Testing effectiveness (Phase 2)Study completedNCT01738646
What this trial is testing

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

Who this might be right for
Recurrent Glioblastoma MultiformeMalignant GliomaAdult Brain Tumor
Duke University 48
Not applicableStudy completedNCT00897611
What this trial is testing

Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma

Who this might be right for
High Grade Glioma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 42
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Testing effectiveness (Phase 2)UnknownNCT02772094
What this trial is testing

Dendritic Cell-Based Tumor Vaccine Adjuvant Immunotherapy of Human Glioblastoma Multiforme (WHO Grade IV Gliomas)

Who this might be right for
Glioblastoma MultiformeGlioblastoma
China Medical University Hospital 50
Early research (Phase 1)Study completedNCT01491893
What this trial is testing

PVSRIPO for Recurrent Glioblastoma (GBM)

Who this might be right for
GBMGlioblastomaGlioma+1 more
Istari Oncology, Inc. 61
Testing effectiveness (Phase 2)Study completedNCT01740258
What this trial is testing

Bevacizumab Beyond Progression (BBP)

Who this might be right for
Malignant GliomaGrade 4 Malignant GliomaGlioblastoma+1 more
Duke University 68
Testing effectiveness (Phase 2)Study completedNCT02986178
What this trial is testing

Lerapolturev in Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Istari Oncology, Inc. 121
Early research (Phase 1)Study completedNCT01156584
What this trial is testing

A Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma

Who this might be right for
GlioblastomaAnaplastic AstrocytomaAnaplastic Oligodendroglioma+1 more
Tocagen Inc. 54
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Early research (Phase 1)Ended earlyNCT04327011
What this trial is testing

A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

Who this might be right for
Glioblastoma MultiformeAstrocytomaGliomas, Malignant
Tocagen Inc. 65
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Early research (Phase 1)Study completedNCT01470794
What this trial is testing

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaAnaplastic Oligodendroglioma+1 more
Tocagen Inc. 58
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