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Results for “H3 K27M Glioma”

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Showing 19 of 0 results

Early research (Phase 1)Looking for participantsNCT05762419
What this trial is testing

FUS Etoposide for DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Columbia University 10
Testing effectiveness (Phase 2)Ended earlyNCT02525692
What this trial is testing

Oral ONC201 in Adult Recurrent Glioblastoma

Who this might be right for
GlioblastomaDiffuse Midline GliomaH3 K27M Glioma+3 more
Jazz Pharmaceuticals 84
Early research (Phase 1)Temporarily pausedNCT06806228
What this trial is testing

Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)

Who this might be right for
Glioblastoma MultiformeDiffuse Midline Glioma, H3 K27M-MutantGliosarcoma+2 more
Petrov, Andrey 10
Early research (Phase 1)Looking for participantsNCT04732065
What this trial is testing

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Who this might be right for
Diffuse Midline Glioma (DMG)GlioblastomaRecurrent Ependymoma+5 more
Sabine Mueller, MD, PhD 208
Early research (Phase 1)Looking for participantsNCT04943848
What this trial is testing

RHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Ann & Robert H Lurie Children's Hospital of Chicago 36
Early research (Phase 1)Active Not RecruitingNCT05835687
What this trial is testing

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Who this might be right for
Central Nervous System NeoplasmsAtypical Teratoid/Rhabdoid TumorDiffuse Midline Glioma, H3 K27M-Mutant+4 more
St. Jude Children's Research Hospital 29
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Early research (Phase 1)Ended earlyNCT04804709
What this trial is testing

Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma, H3 K27M-Mutant
Columbia University 5
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Early research (Phase 1)Looking for participantsNCT07076498
What this trial is testing

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Who this might be right for
Glioma
M.D. Anderson Cancer Center 20
Not applicableLooking for participantsNCT05259605
What this trial is testing

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Who this might be right for
GliomaGlioneuronal TumorChoroid Plexus Tumor+10 more
European Organisation for Research and Treatment of Cancer - EORTC 1,650
Early research (Phase 1)Study completedNCT03696355
What this trial is testing

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
St. Jude Children's Research Hospital 27
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Not applicableNo Longer AvailableNCT06439849
What this trial is testing

Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline Glioma

Who this might be right for
DIPG Brain TumorDiffuse Brainstem GliomaH3 K27M+2 more
Petrov, Andrey
Large-scale testing (Phase 3)Looking for participantsNCT05476939
What this trial is testing

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantDiffuse Midline Glioma, H3K27-altered
Gustave Roussy, Cancer Campus, Grand Paris 433
Testing effectiveness (Phase 2)Ended earlyNCT03295396
What this trial is testing

ONC201 in Adults With Recurrent H3 K27M-mutant Glioma

Who this might be right for
Glioma
Jazz Pharmaceuticals 73
Large-scale testing (Phase 3)Looking for participantsNCT05580562
What this trial is testing

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

Who this might be right for
H3 K27MGlioma
Jazz Pharmaceuticals 510
Early research (Phase 1)Looking for participantsNCT06305910
What this trial is testing

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantRecurrent High Grade Glioma
OX2 Therapeutics 24
Not applicableNo Longer AvailableNCT05518838
What this trial is testing

Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine Glioma
Oblato, Inc.