Early research (Phase 1)Study completedNCT04818632What this trial is testingAZD9833 China PK StudyWho this might be right forER+, HER2-, Metastatic Breast Cancer AstraZeneca 28
Early research (Phase 1)Looking for participantsNCT05683418What this trial is testingEvaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast CancerWho this might be right forHR+/HER2-negative Breast Cancer Totus Medicines 241
Testing effectiveness (Phase 2)Looking for participantsNCT07610720What this trial is testingDalpiciclib, Anti-HER2 Therapy, and Endocrine Therapy for Hormone-Receptor-Positive, HER2-Positive Metastatic Breast CancerWho this might be right forAdvanced/Metastatic Breast CancerHER2-Positive Metastatic Breast Cancer Sun Yat-sen University 57
Not applicableLooking for participantsNCT07376174What this trial is testingThe Prognostic Impact of HER2 Expression in Non-Metastatic HER2-Positive Breast Cancer Treated With Dual HER2-Targeted TherapyWho this might be right forBreast CancerHER2/CEP17 Ratio Shandong Cancer Hospital and Institute 300
Testing effectiveness (Phase 2)Ended earlyNCT04467515What this trial is testingEvaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) CancerWho this might be right forAdvanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment Precirix 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05979220What this trial is testingStudy of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line ChemotherapyWho this might be right forBreast Cancer Shuangyue Liu 178
Not applicableActive Not RecruitingNCT05036252What this trial is testingStudy of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild CardiotoxicityWho this might be right forBreast CancerHER2-positive Breast CancerHER2-positive Metastatic Breast Cancer+5 more Memorial Sloan Kettering Cancer Center 23
Not applicableUnknownNCT02597868What this trial is testingA Multicenter, Randomized Clinical Trail Evaluate Effectiveness and Security of Capecitabine or Endocrinotherapy as a Maintenance Therapy Regimen After the 1st-line Chemotherapy With Capecitabine Combine Regimen in Hormone Receptor Positive and HER2 Negative Metastatic Breast Cancer(Overstep)Who this might be right forBreast Cancer Zhejiang Cancer Hospital 132
Not applicableActive Not RecruitingNCT04597580What this trial is testingPersonalised Disease Monitoring in Metastatic Breast CancerWho this might be right forBreast Cancer MetastaticEstrogen Receptor-positive Breast Cancer The Christie NHS Foundation Trust 97
Not applicableStudy completedNCT02023359What this trial is testingDanish Observational Study of Everolimus Plus Exemestane in Hormone Receptor (HR) Positive, Human Epidermal Growth Factor 2 (HER2) - Metastatic Breast CancerWho this might be right forBreast Cancer Novartis Healthcare A/S 7
Testing effectiveness (Phase 2)Study completedNCT01160718What this trial is testingFulvestrant With or Without AZD6244 in Treating Patients With Advanced Breast Cancer That Progressed After Aromatase Inhibitor TherapyWho this might be right forBreast Cancer Swiss Cancer Institute 46
Testing effectiveness (Phase 2)Looking for participantsNCT06875128What this trial is testingEvaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant DiseaseWho this might be right forMetastatic Breast Cancer in the Liver Delcath Systems Inc. 90
Early research (Phase 1)Looking for participantsNCT06756932What this trial is testingBGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast CancerWho this might be right forHormone-receptor-positive Breast CancerHER2-negative Breast CancerMetastatic Breast Cancer BeOne Medicines 120
Early research (Phase 1)Study completedNCT00485277What this trial is testingA Safety and Immunology Study of a Modified Vaccinia Vaccine for HER-2(+) Metastatic Breast CancerWho this might be right forBreast Cancer Bavarian Nordic 9
Large-scale testing (Phase 3)Looking for participantsNCT06757634What this trial is testingPhase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)Who this might be right forBreast Cancer Celcuity Inc 1,180
Large-scale testing (Phase 3)Active Not RecruitingNCT02246621What this trial is testingNonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast CancerWho this might be right forBreast Cancer Eli Lilly and Company 493
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07340619What this trial is testingClinical Trial Evaluating the Biological Activity of a New Drug Identified as Prifetrastat (PF-07248144), Combined With Fulvestrant for the Treatment of Patients With Hormone Receptor Positive (HR+) and HER2 Negative (HER2-) Breast Cancer Extended to Other Organs.Who this might be right forMetastatic (Stage IV) Melanoma UNICANCER 51
Not applicableLooking for participantsNCT07347600What this trial is testingEvaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast CancerWho this might be right forLocally Advanced Breast CancerMetastatic Breast Cancer Hoffmann-La Roche 500
Testing effectiveness (Phase 2)UnknownNCT02238509What this trial is testingSafety and QoL of Trastuzumab With Lapatinib or Chemiotherapy in MBC and HER2+ Patients Refractory to Anti HER2 TherapiesWho this might be right forMetastatic Breast Cancer Consorzio Oncotech 154
Testing effectiveness (Phase 2)Active Not RecruitingNCT06590857What this trial is testingTrial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.Who this might be right forMetastatic Breast CancerHER2-negative Breast CancerER+ Breast Cancer+7 more RayzeBio, Inc. 16