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Results for “HER-2 Protein Overexpression”

72 trials

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Showing 20 of 72 results

Testing effectiveness (Phase 2)UnknownNCT06055153
What this trial is testing

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

Who this might be right for
Esophageal Squamous CarcinomaHER-2 Protein Overexpression
Changhai Hospital 20
Testing effectiveness (Phase 2)Study completedNCT01828736
What this trial is testing

Efficacy of Combination of Trastuzumab to Gemcitabine - Platinum Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Recurrent Bladder CancerStage IV Bladder CancerTransitional Cell Carcinoma of the Bladder
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie 61
Early research (Phase 1)UnknownNCT04660929
What this trial is testing

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Who this might be right for
HER2-positiveAdenocarcinomaBile Duct Cancer+28 more
Carisma Therapeutics Inc 48
Not applicableEnded earlyNCT02840110
What this trial is testing

Long-Term Follow-Up Study of Subjects Treated With ACTR T Cell Product

Who this might be right for
B Cell LymphomasMultiple MyelomaSolid Tumor+1 more
Cogent Biosciences, Inc. 22
Not applicableEnded earlyNCT00358098
What this trial is testing

Study to Determine the Utility of FES-PET and FDG-PET in the Prediction of Response to Hormone Therapy in Women With Estrogen Positive Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AHS Cancer Control Alberta 51
Very early researchWithdrawnNCT02735798
What this trial is testing

64-Cu Labeled Brain PET/MRI for MM-302 in Advanced HER2+ Cancers With Brain Mets

Who this might be right for
Brain MetastasesDocumented Her2 OverexpressionAdvanced Solid Tumor+1 more
Pamela Munster
Not applicableActive Not RecruitingNCT02295059
What this trial is testing

Omega 3 Fatty Acids and ERPR(-)HER2(+/-) Breast Cancer Prevention

Who this might be right for
Breast Cancer
City of Hope Medical Center 80
Testing effectiveness (Phase 2)Ended earlyNCT02013765
What this trial is testing

Herceptin (Trastuzumab) Monotherapy in Patients With Metastatic Urothelial Cancer

Who this might be right for
Urinary Tract Cancer
Hoffmann-La Roche 5
Early research (Phase 1)WithdrawnNCT04602117
What this trial is testing

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

Who this might be right for
HER2-positive Breast CancerHER2 LowSYD-985+24 more
QuantumLeap Healthcare Collaborative
Early research (Phase 1)Ended earlyNCT05511844
What this trial is testing

Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors

Who this might be right for
HER2-positive Breast CancerHER-2 Protein OverexpressionHER-2 Gene Amplification+1 more
Orum Therapeutics USA, Inc. 25
Testing effectiveness (Phase 2)Study completedNCT01367288
What this trial is testing

Comparative Study of Neoadjuvant Chemotherapy With and Without Zometa for Management of Locally Advanced Breast Cancers

Who this might be right for
Locally Advanced Breast CancerDuctal Histologic TypeWithout Her 2 Overexpression
Hospices Civils de Lyon 53
Not applicableUnknownNCT02136836
What this trial is testing

Investigation of the Proportion of Human Epidermal Growth Factor Receptor 2 Protein Overexpression of Gastric Adenocarcinoma and Prognostic Effect of HER2, and Analysis of Practice Pattern of Herceptin Use in Stage IV Gastric Cancer

Who this might be right for
Stomach Neoplasms
Yonsei University 860
Testing effectiveness (Phase 2)UnknownNCT05135715
What this trial is testing

RC48-ADC in Advanced Melanoma Subjects With HER2 Variant (Mutation, Amplification, Overexpression)

Who this might be right for
Melanoma, Stage IIHER2-positiveAdvanced Melanoma
RemeGen Co., Ltd. 50
Early research (Phase 1)Looking for participantsNCT05868226
What this trial is testing

PRE-I-SPY Phase I/Ib Oncology Platform Program

Who this might be right for
HER2-positive Breast CancerMetastatic CancerMetastatic Breast Cancer+18 more
QuantumLeap Healthcare Collaborative 124
Early research (Phase 1)Looking for participantsNCT07361562
What this trial is testing

A Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, AdultERBB2 Altered Breast CancerERBB2 Gene Amplification+3 more
Cogent Biosciences, Inc. 100
Testing effectiveness (Phase 2)UnknownNCT05720533
What this trial is testing

Disitamab Vedotin Combined With Sintilimab as First-line Treatment of Elderly Patients With Gastric Cancer

Who this might be right for
Gastric Cancer
Tianjin Medical University Cancer Institute and Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06695845
What this trial is testing

Zanidatamab in Patients With HER2-expressing Tumors

Who this might be right for
Breast CancerGastric CancerEsophageal Cancer+9 more
Jazz Pharmaceuticals 200
Testing effectiveness (Phase 2)Study completedNCT00401427
What this trial is testing

HERVIN: Trastuzumab and Vinorelbine in Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
National Cancer Institute, Naples 50
Early research (Phase 1)Study completedNCT05904730
What this trial is testing

Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations

Who this might be right for
Breast CancerOvarian CancerBreast Neoplasms+5 more
Lynkcell Europe 10
Early research (Phase 1)Ended earlyNCT03410927
What this trial is testing

TAS0728 in Patients With Solid Tumors With HER2 or HER3 Abnormalities

Who this might be right for
Advanced Solid Tumors With HER2 AbnormalitiesAdvanced Solid Tumors With HER3 Abnormalities
Taiho Oncology, Inc. 19
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