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Results for “HER2 + Gastric Cancer”

355 trials

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Showing 20 of 355 results

Testing effectiveness (Phase 2)Looking for participantsNCT07474324
What this trial is testing

Disitamab Vedotin Combined With SOX Regimen Versus SOX Alone as Adjuvant Therapy for HER2-Moderate/High Expressing Stage Ⅲ Gastric Cancer: A Prospective, Multicenter, Randomized, Phase Ⅱ Clinical Trial

Who this might be right for
GC/GEJC
The First Affiliated Hospital with Nanjing Medical University 124
Large-scale testing (Phase 3)Study completedNCT00486954
What this trial is testing

Lapatinib in Combination With Weekly Paclitaxel in Patients With ErbB2 Amplified Advanced Gastric Cancer

Who this might be right for
Neoplasms, Gastrointestinal Tract
GlaxoSmithKline 273
Not applicableStudy completedNCT05540145
What this trial is testing

Neo-Sequence 1: Neoadjuvant Chemotherapy With or Without Antiangiogenesis and Sequential Immunotherapy for HER2-negative MMR-proficient Locally Advanced Gastric or Gastroesophageal Adenocarcinoma

Who this might be right for
Gastric Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 70
Testing effectiveness (Phase 2)Ended earlyNCT01402401
What this trial is testing

Phase II of AUY922 in Second-line Gastric Cancer in Combination With Trastuzumab in HER2 Positive Patients

Who this might be right for
Advanced Gastric Cancer
Novartis Pharmaceuticals 21
Testing effectiveness (Phase 2)Looking for participantsNCT06650332
What this trial is testing

Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients

Who this might be right for
Metastatic HER2 Positive Gastroesophageal Junction Cancer
Zhejiang Cancer Hospital 90
Not applicableLooking for participantsNCT05993234
What this trial is testing

Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)

Who this might be right for
HER2-positive Advanced Gastric CancerHER2-positive Gastroesophageal Junction Adenocarcinoma
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company 257
Not applicableStudy completedNCT05955833
What this trial is testing

89Zr-DFO*-Trastuzumab PET in Patients With Gastric or Breast Cancer - a Pilot Study

Who this might be right for
Breast CancerMetastatic Breast CancerHER2-positive Breast Cancer+3 more
Amsterdam UMC, location VUmc 6
Early research (Phase 1)Study completedNCT01576666
What this trial is testing

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Who this might be right for
Dose EscalationSafetyPreliminary Efficacy+9 more
Novartis Pharmaceuticals 120
Large-scale testing (Phase 3)Looking for participantsNCT05427383
What this trial is testing

KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy

Who this might be right for
Stomach Cancer
Shanghai JMT-Bio Inc. 286
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06888037
What this trial is testing

Fruquintinib Combined With PD-1 Inhibitor as First-line Maintenance Therapy for Advanced Gastric Cancer

Who this might be right for
Gastric AdenocarcinomaGEJ AdenocarcinomaFirst-line Therapy+3 more
Ruijin Hospital 55
Testing effectiveness (Phase 2)Looking for participantsNCT07523529
What this trial is testing

Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors

Who this might be right for
Advanced UnresectableMetastatic
Beijing Biotech 72
Testing effectiveness (Phase 2)Study completedNCT01396707
What this trial is testing

Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC): Her+XELOX

Who this might be right for
Metastatic or Recurrent Gastric AdenocarcinomaHer-2 Positive Gastric Cancer
Asan Medical Center 55
Early research (Phase 1)UnknownNCT04660929
What this trial is testing

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Who this might be right for
HER2-positiveAdenocarcinomaBile Duct Cancer+28 more
Carisma Therapeutics Inc 48
Testing effectiveness (Phase 2)Looking for participantsNCT05150691
What this trial is testing

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Who this might be right for
HER2-positive Advanced Solid Tumor
DualityBio Inc. 796
Testing effectiveness (Phase 2)Looking for participantsNCT06330064
What this trial is testing

Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

Who this might be right for
Recurrent or Metastatic Solid Tumors
Daiichi Sankyo 520
Not applicableEnded earlyNCT02358863
What this trial is testing

Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and Stomach

Who this might be right for
Esophageal CancerGastric Cancer
Georgetown University 13
Testing effectiveness (Phase 2)Ended earlyNCT07040059
What this trial is testing

A Phase 1b/2 Clinical Trial Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
HER 2 Positive Gastric CancerGastroesophageal Junction Adenocarcinoma
Aurigene Discovery Technologies Limited 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Testing effectiveness (Phase 2)Looking for participantsNCT07070466
What this trial is testing

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

Who this might be right for
Stomach Cancer Stage IVEsophagus CancerStomach Cancer
Massachusetts General Hospital 40
Large-scale testing (Phase 3)Ended earlyNCT01641939
What this trial is testing

Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
Hoffmann-La Roche 415
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