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Results for “HER2 Negative Gastric Cancer”

89 trials

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Showing 20 of 89 results

Not applicableUnknownNCT06349044
What this trial is testing

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Who this might be right for
Her-2 Negative Adenocarcinoma of the Gastro-oesophageal Junction/Gastric AdenocarcinomaHepatocellular CarcinomaBiliary Tract Carcinoma+1 more
Zhejiang Cancer Hospital 120
Testing effectiveness (Phase 2)Ended earlyNCT05188209
What this trial is testing

Evaluate the Efficacy and Safety of MRG003 in Patients With Advanced Gastric Cancer.

Who this might be right for
Advanced or Metastatic Gastric CancerAdvanced or Metastatic Gastroesophageal Junction Carcinoma
Lepu Biopharma Co., Ltd. 6
Testing effectiveness (Phase 2)Looking for participantsNCT07070466
What this trial is testing

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

Who this might be right for
Stomach Cancer Stage IVEsophagus CancerStomach Cancer
Massachusetts General Hospital 40
Early research (Phase 1)Looking for participantsNCT06999187
What this trial is testing

DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

Who this might be right for
Triple Negative Breast CancerHER2-negative Breast CancerNon Small Cell Lung Cancer+9 more
Dren Bio 96
Testing effectiveness (Phase 2)Study completedNCT04742959
What this trial is testing

Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorCholangiocarcinomaHER2-negative Breast Cancer+8 more
TransThera Sciences (Nanjing), Inc. 203
Large-scale testing (Phase 3)Active Not RecruitingNCT05144854
What this trial is testing

Evaluate the Efficacy and Safety of ONO-4538 in Combination With Ipilimumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)

Who this might be right for
Gastric Cancer
Ono Pharmaceutical Co., Ltd. 626
Large-scale testing (Phase 3)Active Not RecruitingNCT03653507
What this trial is testing

Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.
Early research (Phase 1)Study completedNCT02240212
What this trial is testing

Study of Afuresertib Combined With Paclitaxel in Gastric Cancer

Who this might be right for
Cancer
Novartis Pharmaceuticals 29
Early research (Phase 1)Active Not RecruitingNCT02264678
What this trial is testing

Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents

Who this might be right for
Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer
AstraZeneca 358
Testing effectiveness (Phase 2)WithdrawnNCT02344810
What this trial is testing

C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer

Who this might be right for
Adenocarcinoma of the EsophagusAdenocarcinoma of the Gastroesophageal JunctionDiffuse Adenocarcinoma of the Stomach+11 more
Eastern Cooperative Oncology Group
Testing effectiveness (Phase 2)Active Not RecruitingNCT06256328
What this trial is testing

Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)

Who this might be right for
Gastric Cancer
Ono Pharmaceutical Co., Ltd. 226
Testing effectiveness (Phase 2)UnknownNCT03817411
What this trial is testing

Telatinib in Combination With Capecitabine/ Oxaliplatin in 1st Line Gastric or GEJ Cancer

Who this might be right for
Gastric Cancer
Taizhou EOC Pharma Co., Ltd. 90
Large-scale testing (Phase 3)Study completedNCT02445209
What this trial is testing

Comparison of Efficacy and Frequency of Adverse Events of 1st Line Palliative Chemotherapy EOX and mDCF Regimens in Advanced HER2-negative Gastric Carcinoma

Who this might be right for
HER2 Negative Gastric Cancer
Jagiellonian University 56
Not applicableNot Yet RecruitingNCT07191405
What this trial is testing

Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors

Who this might be right for
ImmunotherapyChemotherapy
Second Affiliated Hospital, Zhejiang University, School of Medicine 156
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802876
What this trial is testing

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors

Who this might be right for
MSI-H Colorectal CancerMelanomaAnal Carcinoma+28 more
SOLTI Breast Cancer Research Group 184
Early research (Phase 1)Looking for participantsNCT05969041
What this trial is testing

Study of MT-302 in Adults With Advanced or Metastatic Epithelial Tumors

Who this might be right for
Epithelial Tumors, Malignant
Myeloid Therapeutics 48
Testing effectiveness (Phase 2)Study completedNCT01590719
What this trial is testing

Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2) Negative Gastroesophageal Cancer

Who this might be right for
Gastric Cancer
Hoffmann-La Roche 123
Very early researchEnrolling By InvitationNCT07356466
What this trial is testing

Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric (Stomach) Cancer
Fujian Medical University 100
Large-scale testing (Phase 3)Study completedNCT01662869
What this trial is testing

Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer

Who this might be right for
Gastric Cancer
Hoffmann-La Roche 564
Testing effectiveness (Phase 2)Looking for participantsNCT06750185
What this trial is testing

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 248
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