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Results for “HER2 Positive Advanced Solid Tumors”

140 trials

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Showing 20 of 140 results

Early research (Phase 1)Looking for participantsNCT04872166
What this trial is testing

BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

Who this might be right for
Advanced Solid TumorMetastatic Breast Cancer
Edgewood Oncology Inc. 112
Testing effectiveness (Phase 2)UnknownNCT04934514
What this trial is testing

Clinical Study of IAH0968 in Patients With HER2-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
SUNHO（China）BioPharmaceutical CO., Ltd. 97
Testing effectiveness (Phase 2)Ended earlyNCT01569412
What this trial is testing

Open Label, Dose Escalating Study With Ertumaxomab In Patients With HER-2/Neu Expressing Advanced Solid Tumors

Who this might be right for
Her2/Neu Positive Advanced Solid Tumors
Krankenhaus Nordwest 14
Not applicableLooking for participantsNCT07030569
What this trial is testing

RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

Who this might be right for
RadiomicRadiomicsBreast Cancer Metastatic+13 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 500
Testing effectiveness (Phase 2)Looking for participantsNCT05681650
What this trial is testing

HER2 Targeted HypoSti.CAR-T Cells in HER2 Positive Advanced Solid Tumors

Who this might be right for
HER2 Positive Advanced Solid Tumors
Chinese PLA General Hospital 30
Early research (Phase 1)Study completedNCT03219268
What this trial is testing

MGD013 in Patients With Unresectable or Metastatic Neoplasms

Who this might be right for
Advanced Solid TumorsHematologic NeoplasmsOvarian Cancer+7 more
MacroGenics 277
Testing effectiveness (Phase 2)WithdrawnNCT07570966
What this trial is testing

Study of ERW316 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Who this might be right for
Advanced HR+/HER2- Breast CancerAdvanced CCNE1-amplified Solid TumorsMetastatic Castration-resistant Prostate Cancer (mCRPC)
Novartis Pharmaceuticals
Early research (Phase 1)Ended earlyNCT03680560
What this trial is testing

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

Who this might be right for
Solid TumorHER-2 Protein Overexpression
Cogent Biosciences, Inc. 6
Testing effectiveness (Phase 2)UnknownNCT04151329
What this trial is testing

A Phase I Clinical Trial of BAT1306 and BAT8001 Injection in Patients With Solid Tumor

Who this might be right for
Solid Tumor
Bio-Thera Solutions 72
Early research (Phase 1)Study completedNCT00803556
What this trial is testing

Clinical Trial of the Combination of Intravenous Alvespimycin (KOS-1022), Trastuzumab With or Without Paclitaxel in Patients With Advanced Solid Tumor Malignancies or Her2 Positive Metastatic Breast Cancer Who Have Previously Failed Trastuzumab Therapy

Who this might be right for
Solid TumorBreast Cancer
Bristol-Myers Squibb 29
Testing effectiveness (Phase 2)Study completedNCT04521179
What this trial is testing

Study of KN026 Combined With KN046 in Patients With Locally Advanced HER2-positive Solid Tumors

Who this might be right for
HER2-positive Solid Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd 102
Early research (Phase 1)Looking for participantsNCT06625775
What this trial is testing

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultMetastatic Breast CancerAdvanced Breast Cancer+8 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 392
Testing effectiveness (Phase 2)Active Not RecruitingNCT04492488
What this trial is testing

MRG002 in Patients with HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

Who this might be right for
Advanced Solid TumorsAdvanced or Metastatic Gastric CancerAdvanced or Metastatic Gastroesophageal Junction Cancer
Shanghai Miracogen Inc. 129
Early research (Phase 1)Looking for participantsNCT07318805
What this trial is testing

Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Breast CancerMetastatic Breast Cancer (HR+/ HER2-)Colorectal Cancer+2 more
Pfizer 260
Testing effectiveness (Phase 2)Looking for participantsNCT06726148
What this trial is testing

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

Who this might be right for
Advanced HR+/HER2- Breast CancerAdvanced CCNE1-amplified Solid TumorsExtensive-stage Small Cell Lung Cancer
Novartis Pharmaceuticals 280
Early research (Phase 1)Temporarily pausedNCT04650451
What this trial is testing

Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors

Who this might be right for
HER-2 Gene AmplificationHER2-positive Gastric CancerHER2-positive Breast Cancer+2 more
Bellicum Pharmaceuticals 220
Testing effectiveness (Phase 2)Active Not RecruitingNCT04550494
What this trial is testing

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate Carcinoma+28 more
National Cancer Institute (NCI) 29
Testing effectiveness (Phase 2)Looking for participantsNCT07486089
What this trial is testing

Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)

Who this might be right for
Breast Cancer (Locally Advanced or Metastatic)HER2-positive Breast CancerTriple-Negative Breast Cancer (TNBC)
Beijing Biotech 60
Early research (Phase 1)Study completedNCT02881138
What this trial is testing

RC48-ADC in Subjects With HER2-Positive Advanced Malignant Solid Tumors

Who this might be right for
Solid Tumors
RemeGen Co., Ltd. 24
Testing effectiveness (Phase 2)Looking for participantsNCT07510802
What this trial is testing

Dual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBC

Who this might be right for
Breast Cancer (Advanced/Metastatic)HER2-positive Breast CancerTriple-negative Breast Cancer
Beijing Biotech 60
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