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Results for “HER2-Positive Primary Breast Cancer”

66 trials

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Showing 20 of 66 results

Large-scale testing (Phase 3)Study completedNCT01966471
What this trial is testing

Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Operable HER2-Positive Primary Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 1,846
Testing effectiveness (Phase 2)Ended earlyNCT03519178
What this trial is testing

PF-06873600 in People With Cancer

Who this might be right for
HR+ HER2- Metastatic Breast Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Triple Negative Breast Cancer, Male Breast Cancer
Pfizer 155
Large-scale testing (Phase 3)Active Not RecruitingNCT04622319
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Who this might be right for
HER2-Positive Primary Breast CancerResidual Invasive Breast Cancer
Daiichi Sankyo 1,600
Testing effectiveness (Phase 2)Ended earlyNCT00820924
What this trial is testing

Study of Lapatinib in Breast Cancer Patients With HER-2 Non-amplified Primary Tumors and HER-2 Positive or EGFR Positive Circulating Tumor Cells

Who this might be right for
Neoplasms, Breast
GlaxoSmithKline 23
Testing effectiveness (Phase 2)WithdrawnNCT00434031
What this trial is testing

CETRA: Neoadjuvant Caelyx and Trastuzumab in Her-2 Positive Breast Cancer

Who this might be right for
Breast Cancer
National Cancer Institute, Naples
Large-scale testing (Phase 3)Looking for participantsNCT03561740
What this trial is testing

The Addition of Metronomic Capecitabine to Standard Adjuvant Therapy in High Risk HER2+ BC paTients

Who this might be right for
Breast Cancer
Sun Yat-sen University 794
Not applicableNot Yet RecruitingNCT07198672
What this trial is testing

Primary Prevention of Thrombocytopenia Associated With T-DM1 Therapy in HER2 Positive Breast Cancer With Herombopag

Who this might be right for
HER2-positive Breast Cancer
Zhenzhen Liu 45
Testing effectiveness (Phase 2)Ended earlyNCT00674414
What this trial is testing

Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery

Who this might be right for
Breast Cancer
UNICANCER 82
Large-scale testing (Phase 3)Study completedNCT01772472
What this trial is testing

Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Who this might be right for
Breast Cancer
Hoffmann-La Roche 1,486
Large-scale testing (Phase 3)Study completedNCT01358877
What this trial is testing

Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 4,804
Early research (Phase 1)Ended earlyNCT05194072
What this trial is testing

Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsPeritoneal NeoplasmsFallopian Tube Neoplasms+8 more
Seagen, a wholly owned subsidiary of Pfizer 250
Testing effectiveness (Phase 2)Study completedNCT02760030
What this trial is testing

Endocrine Therapy Fulvestrant & Palbociclib or Aromatase Inhibitor Therapy in Treating Older Patients With Hormone Responsive Breast Cancer That Cannot Be Removed by Surgery

Who this might be right for
Estrogen Receptor and/or Progesterone Receptor PositiveHER2/Neu NegativeStage IA Breast Cancer+6 more
Ohio State University Comprehensive Cancer Center 14
Testing effectiveness (Phase 2)Study completedNCT04588298
What this trial is testing

Investigate the Biological Effects of AZD9833 in Women With ER-positive, HER2 Negative Primary Breast Cancer

Who this might be right for
HER2-negative Breast Cancer
AstraZeneca 135
Not applicableEnded earlyNCT05068726
What this trial is testing

Clinical Utility of FES F18 PET/CT in Metastatic Breast Cancer Patients

Who this might be right for
Metastatic Breast Cancer
GE Healthcare 51
Not applicableLooking for participantsNCT04660435
What this trial is testing

To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer

Who this might be right for
Metastatic Breast CancerER Positive Breast CancerHER2-negative Breast Cancer
Fondazione Sandro Pitigliani 150
Early research (Phase 1)Study completedNCT03236974
What this trial is testing

Study to Compare the Effects of AZD9496 vs Fulvestrant in Breast Cancer.

Who this might be right for
Postmenopausal Women With ER+ HER2- Primary Breast Cancer
AstraZeneca 49
Testing effectiveness (Phase 2)Ended earlyNCT01185509
What this trial is testing

Trastuzumab and Vinorelbine in Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic Breast Cancer
Dana-Farber Cancer Institute 31
Testing effectiveness (Phase 2)Study completedNCT02005887
What this trial is testing

TRial on the Endocrine Activity of Neoadjuvant Degarelix

Who this might be right for
Breast Cancer Invasive Nos
ETOP IBCSG Partners Foundation 51
Early research (Phase 1)Active Not RecruitingNCT04692831
What this trial is testing

Testing a New Imaging Agent to Identify Cancer

Who this might be right for
HER-2 Positive Malignant Carcinoma of BreastHER-2 Protein OverexpressionHER2-positive Metastatic Breast Cancer
Memorial Sloan Kettering Cancer Center 60
Large-scale testing (Phase 3)Study completedNCT00553358
What this trial is testing

Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study

Who this might be right for
Neoplasms, Breast
Novartis Pharmaceuticals 455
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