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Results for “HER2-Positive Primary Breast Cancer”

67 trials

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Showing 20 of 67 results

Large-scale testing (Phase 3)Study completedNCT00045032
What this trial is testing

Herceptin (Trastuzumab) in Treating Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Primary Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 5,099
Large-scale testing (Phase 3)Study completedNCT00490139
What this trial is testing

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

Who this might be right for
Neoplasms, Breast
Novartis Pharmaceuticals 8,381
Testing effectiveness (Phase 2)Study completedNCT03628066
What this trial is testing

Biological and Clinical Effects of Palbociclib With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Breast Cancer

Who this might be right for
Breast Cancer
NSABP Foundation Inc 24
Testing effectiveness (Phase 2)Study completedNCT02682693
What this trial is testing

Denosumab as an add-on Neoadjuvant Treatment (GeparX)

Who this might be right for
Breast Cancer Female NOSTubular Breast Cancer Stage IIMucinous Breast Cancer Stage II+4 more
GBG Forschungs GmbH 780
Testing effectiveness (Phase 2)Study completedNCT01816594
What this trial is testing

NeoPHOEBE: Neoadjuvant Trastuzumab + BKM120 in Combination With Weekly Paclitaxel in HER2-positive Primary Breast Cancer

Who this might be right for
HER2-positive Newly Diagnosed, Primary Breast Cancer
Novartis Pharmaceuticals 50
Large-scale testing (Phase 3)Active Not RecruitingNCT04622319
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Who this might be right for
HER2-Positive Primary Breast CancerResidual Invasive Breast Cancer
Daiichi Sankyo 1,600
Testing effectiveness (Phase 2)Ended earlyNCT01919229
What this trial is testing

A Pharmacodynamics Pre-surgical Study of LEE011 in Early Breast Cancer Patients (MONALEESA-1)

Who this might be right for
Early Breast Cancer
Novartis Pharmaceuticals 14
Not applicableStudy completedNCT00898898
What this trial is testing

Studying Tissue Samples From Women With Breast Cancer Who Were Treated on Clinical Trial NCCTG-N9831

Who this might be right for
Breast Cancer
Alliance for Clinical Trials in Oncology 2,837
Not applicableApproved For MarketingNCT04100694
What this trial is testing

Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Who this might be right for
NRG1 FusionPancreatic CancerNon Small Cell Lung Cancer+8 more
Merus B.V.
Large-scale testing (Phase 3)Study completedNCT04109066
What this trial is testing

Study of Nivolumab Versus Placebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy in Participants With High-risk, Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor 2-Negative (HER2-) Primary Breast Cancer

Who this might be right for
Breast Cancer
Bristol-Myers Squibb 521
Large-scale testing (Phase 3)Study completedNCT01358877
What this trial is testing

Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 4,804
Large-scale testing (Phase 3)Looking for participantsNCT05063136
What this trial is testing

Adjuvant Metronomic Capecitabine Plus Endocrine Therapy for HR+/HER2- Primary Breast Cancer

Who this might be right for
Breast Cancer
Henan Cancer Hospital 1,979
Testing effectiveness (Phase 2)Study completedNCT04588298
What this trial is testing

Investigate the Biological Effects of AZD9833 in Women With ER-positive, HER2 Negative Primary Breast Cancer

Who this might be right for
HER2-negative Breast Cancer
AstraZeneca 135
Testing effectiveness (Phase 2)Study completedNCT02005887
What this trial is testing

TRial on the Endocrine Activity of Neoadjuvant Degarelix

Who this might be right for
Breast Cancer Invasive Nos
ETOP IBCSG Partners Foundation 51
Testing effectiveness (Phase 2)Ended earlyNCT01185509
What this trial is testing

Trastuzumab and Vinorelbine in Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic Breast Cancer
Dana-Farber Cancer Institute 31
Testing effectiveness (Phase 2)Study completedNCT01548677
What this trial is testing

Efficacy Study of Herceptin to Treat HER2-negative CTC Breast Cancer

Who this might be right for
Breast CancerHuman Epidermal Growth Factor 2 Negative Carcinoma of BreastCirculating Tumor Cells
European Organisation for Research and Treatment of Cancer - EORTC 1,317
Testing effectiveness (Phase 2)Active Not RecruitingNCT01937117
What this trial is testing

Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer

Who this might be right for
Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 88
Not applicableUnknownNCT05880160
What this trial is testing

Safety of Withdrawal of Pharmacological Treatment for Recovered HER2 Targeted Therapy Related Cardiac Dysfunction

Who this might be right for
CardiotoxicityHER2-positive Breast CancerHeart Failure+1 more
University College, London 90
Large-scale testing (Phase 3)Study completedNCT02422615
What this trial is testing

Study of Efficacy and Safety of LEE011 in Men and Postmenopausal Women With Advanced Breast Cancer.

Who this might be right for
Advanced Breast Cancer
Novartis Pharmaceuticals 726
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07417241
What this trial is testing

SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study

Who this might be right for
Breast CancerHER2-positive Breast Cancer
Peking University Cancer Hospital & Institute 100
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