Not applicableActive Not RecruitingNCT07387874What this trial is testingA Real-World Study of Trastuzumab Rezetecan in HER2+ Solid TumorsWho this might be right forRecurrent or Metastatic Solid Tumors Lixiaoling 30
Testing effectiveness (Phase 2)Looking for participantsNCT07117851What this trial is testingDisitamab Vedotin + Bicalutamide in HER2/AR-Positive Scrotal Paget's DiseaseWho this might be right forExtramammary Paget DiseaseScrotum Disease Fudan University 20
Post-approval studies (Phase 4)Not Yet RecruitingNCT05488353What this trial is testingA Clinical Study of Disitamab Vedotin for Injection Combined With Penpulimab Injection in Neoadjuvant Therapy for Patients With HER2-expressing Cisplatin-intolerant cT2-T4aNxM0 Bladder Urothelial CarcinomaWho this might be right forBladder Cancer Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 48
Large-scale testing (Phase 3)Looking for participantsNCT06819007What this trial is testingStudy of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)Who this might be right forOvarian Cancer Daiichi Sankyo 582
Large-scale testing (Phase 3)Ended earlyNCT00272987What this trial is testingErbB2 Over-expressing Metastatic Breast Cancer Study Using Paclitaxel, Trastuzumab, and LapatinibWho this might be right forNeoplasms, Breast Novartis Pharmaceuticals 63
Early research (Phase 1)Study completedNCT00647114What this trial is testingTest V930/V932 in Patients With Cancers Expressing Human Epidermal Growth Factor Receptor 2 (HER-2) and/or Carcinoembryonic Antigen (CEA)(V930-003)(COMPLETED)Who this might be right forCancer Merck Sharp & Dohme LLC 41
Early research (Phase 1)Study completedNCT03821233What this trial is testingA Dose Finding Study of ZW49 in Patients With HER2-Positive CancersWho this might be right forHER2-expressing Cancers Zymeworks BC Inc. 112
Not applicableStudy completedNCT06386263What this trial is testingHER-TEMPO - Real World Treatment-related Outcomes on T-DXd in CanadaWho this might be right forUnresectable Breast CancerMetastatic Breast CancerHER2-low Expressing Breast Cancer+1 more AstraZeneca 22
Early research (Phase 1)Looking for participantsNCT06293898What this trial is testingOpen Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid TumorsWho this might be right forEndometrial CancerCervical CancerOvarian Cancer+7 more SystImmune Inc. 280
Early research (Phase 1)Active Not RecruitingNCT03448042What this trial is testingRunimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing CancersWho this might be right forSolid Tumors Genentech, Inc. 123
Testing effectiveness (Phase 2)Ended earlyNCT05091528What this trial is testingA Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive CancersWho this might be right forHER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more Silverback Therapeutics 2
Early research (Phase 1)Study completedNCT03366428What this trial is testingPhase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast CancerWho this might be right forMalignant Neoplasm of Breast Daiichi Sankyo Co., Ltd. 51
Large-scale testing (Phase 3)Study completedNCT02581462What this trial is testingFLOT vs. FLOT/Herceptin/Pertuzumab for Perioperative Therapy of HER-2 Expressing Gastric or GEJ CancerWho this might be right forStomach CancerGastroesophageal Junction Cancer Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 81
Testing effectiveness (Phase 2)Study completedNCT00284180What this trial is testingVinflunine Plus Trastuzumab in Human Epidermal Growth Factor Receptor 2 (HER2neu) Over-Expressing Metastatic Breast CancerWho this might be right forBreast NeoplasmsBreast Cancer SCRI Development Innovations, LLC 32
Early research (Phase 1)Study completedNCT03523572What this trial is testingTrastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial CancerWho this might be right forBreast CancerUrothelial Carcinoma Daiichi Sankyo 86
Testing effectiveness (Phase 2)Ended earlyNCT01779050What this trial is testingEffect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor CellsWho this might be right forBreast Neoplasms Washington University School of Medicine 7
Testing effectiveness (Phase 2)Study completedNCT00558103What this trial is testingPazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Inflammatory Breast CancerWho this might be right forNeoplasms, Breast GlaxoSmithKline 163
Early research (Phase 1)Study completedNCT02952729What this trial is testingStudy of Antibody Drug Conjugate in Patients With Advanced Breast Cancer Expressing HER2Who this might be right forAdvanced Breast CancerAdvanced Nonsmall Cell Lung CancerAdvanced Gastric Cancer Mersana Therapeutics 120
Early research (Phase 1)Study completedNCT02576548What this trial is testingMEDI4276 in Adults Subjects With Select HER2-expressing Advanced Solid Tumors.Who this might be right forHER2 Expressing Breast or Gastric/Stomach Cancers MedImmune LLC 47
Early research (Phase 1)Study completedNCT03383692What this trial is testingStudy of DS-8201a for Participants With Advanced Solid Malignant TumorsWho this might be right forNeoplasm Metastasis Daiichi Sankyo Co., Ltd. 40