Early research (Phase 1)Study completedNCT02276300What this trial is testingHER2-Peptide Vaccination of Patients With Solid TumorsWho this might be right forGastric CancerBreast Cancer Technical University of Munich 2
Testing effectiveness (Phase 2)UnknownNCT05912205What this trial is testingDisitamab Vedotin Combined With Radiotherapy for Bladder PreservationWho this might be right forUrothelial Carcinoma Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 30
Not applicableUnknownNCT06857747What this trial is testingDisitamab Vedotin in Combination with Metronomic Chemotherapy in Advanced HER2-expressing Breast Cancer.Who this might be right forBreast Cancer QIAO LI 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07150208What this trial is testingT-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain MetastasisWho this might be right forBreast Cancer With Brain MetastasisHER2-low Expressing Breast Cancer Fudan University 140
Not applicableLooking for participantsNCT05945732What this trial is testingDESTINY Breast Respond HER2-(Ultra)Low EuropeWho this might be right forUnresectable Breast CancerMetastatic Breast CancerHER2-low Expressing Breast Cancer+1 more Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company 2,295
Early research (Phase 1)Active Not RecruitingNCT00902044What this trial is testingHer2 Chimeric Antigen Receptor Expressing T Cells in Advanced SarcomaWho this might be right forSarcoma Baylor College of Medicine 36
Testing effectiveness (Phase 2)Ended earlyNCT05091528What this trial is testingA Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive CancersWho this might be right forHER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more Silverback Therapeutics 2
Testing effectiveness (Phase 2)Looking for participantsNCT06026657What this trial is testingGemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast CancerWho this might be right forAnatomic Stage IV Breast Cancer AJCC v8HER2-Negative Breast Carcinoma Margaret Gatti-Mays 42
Testing effectiveness (Phase 2)Study completedNCT01730612What this trial is testingImmunoTEP au 68-Ga- IMP-288 for Patients With a Recurrence of HER2 Negative Breast Carcinoma Expressing CEAWho this might be right forHER2 Negative Breast Carcinoma Expressing CEA Nantes University Hospital 23
Large-scale testing (Phase 3)Looking for participantsNCT06221748What this trial is testingDV Combined With Cadonilimab in Subjects With HER2-expressing Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on First-line TherapyWho this might be right forGastric CancerGastroesophageal Junction Adenocarcinoma RemeGen Co., Ltd. 90
Early research (Phase 1)Not Yet RecruitingNCT07036185What this trial is testingA Clinical Trail of KJ015 in Patients With HER2-Expressing Solid TumorsWho this might be right forGastric/Gastroesophageal Junction CancerBreast CancerColorectal Cancer+3 more Shanghai Bao Pharmaceuticals Co., Ltd. 66
Early research (Phase 1)Ended earlyNCT05511844What this trial is testingStudy of ORM-5029 in Subjects With HER2-Expressing Advanced Solid TumorsWho this might be right forHER2-positive Breast CancerHER-2 Protein OverexpressionHER-2 Gene Amplification+1 more Orum Therapeutics USA, Inc. 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT04482309What this trial is testingT-DXd in Patients With Selected HER2 Expressing TumorsWho this might be right forPart 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal CancerPart 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer AstraZeneca 477
Testing effectiveness (Phase 2)Looking for participantsNCT06015048What this trial is testingA Trial of SHR-A1811 Combined With Other Antitumor Therapies in Advanced Solid Tumors.Who this might be right forHER2-expressing Advanced Solid Tumors Jiangsu HengRui Medicine Co., Ltd. 364
Early research (Phase 1)Study completedNCT00291473What this trial is testingSafety and Immunogenicity of CHP-HER2 and CHP-NY-ESO-1 Protein With OK-432 in Antigen-Expressing CancersWho this might be right forEsophageal CancerLung CancerStomach Cancer+2 more Ludwig Institute for Cancer Research 9
Large-scale testing (Phase 3)Study completedNCT03130790What this trial is testingVarlitinib in Combination With mFOLFOX6 for Advanced or Metastatic Gastric Cancer (First Line)Who this might be right forGastric Cancer ASLAN Pharmaceuticals 52
Early research (Phase 1)Looking for participantsNCT07137416What this trial is testingTesting the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast CancerWho this might be right forAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast Carcinoma+13 more National Cancer Institute (NCI) 36
Large-scale testing (Phase 3)Looking for participantsNCT05302284What this trial is testingRC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial CarcinomaWho this might be right forUrothelial CarcinomaHER2-expressing RemeGen Co., Ltd. 452
Testing effectiveness (Phase 2)Active Not RecruitingNCT05625087What this trial is testingDetection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or RibociclibWho this might be right forBreast Cancer Stage IV UNICANCER 162
Early research (Phase 1)Study completedNCT06710990What this trial is testingInvestigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast CancerWho this might be right forAdvanced Breast Cancer Jiangsu HengRui Medicine Co., Ltd. 17