Early research (Phase 1)Study completedNCT03821233What this trial is testingA Dose Finding Study of ZW49 in Patients With HER2-Positive CancersWho this might be right forHER2-expressing Cancers Zymeworks BC Inc. 112
Testing effectiveness (Phase 2)Ended earlyNCT05091528What this trial is testingA Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive CancersWho this might be right forHER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more Silverback Therapeutics 2
Early research (Phase 1)Study completedNCT02952729What this trial is testingStudy of Antibody Drug Conjugate in Patients With Advanced Breast Cancer Expressing HER2Who this might be right forAdvanced Breast CancerAdvanced Nonsmall Cell Lung CancerAdvanced Gastric Cancer Mersana Therapeutics 120
Testing effectiveness (Phase 2)WithdrawnNCT04464967What this trial is testingSafety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR CancersWho this might be right forAdvanced Solid TumorMetastatic CancerHER2-positive Breast Cancer+14 more NKGen Biotech, Inc.
Early research (Phase 1)Not Yet RecruitingNCT07036185What this trial is testingA Clinical Trail of KJ015 in Patients With HER2-Expressing Solid TumorsWho this might be right forGastric/Gastroesophageal Junction CancerBreast CancerColorectal Cancer+3 more Shanghai Bao Pharmaceuticals Co., Ltd. 66
Early research (Phase 1)Study completedNCT00005023What this trial is testingVaccine Therapy Plus Sargramostim in Treating Patients With Stage III or Stage IV CancerWho this might be right forBreast CancerLung CancerOvarian Cancer University of Washington
Early research (Phase 1)Looking for participantsNCT05969041What this trial is testingStudy of MT-302 in Adults With Advanced or Metastatic Epithelial TumorsWho this might be right forEpithelial Tumors, Malignant Myeloid Therapeutics 48
Early research (Phase 1)Active Not RecruitingNCT06714617What this trial is testingEvaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid TumorsWho this might be right forBreast Cancer Stage IIIHER2-positive Metastatic Breast CancerUnresectable Breast Carcinoma+11 more SystImmune Inc. 120
Early research (Phase 1)Looking for participantsNCT07334119What this trial is testingSafety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid TumorsWho this might be right forHER2-Expressing Solid Tumors Myeloid Therapeutics 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04561362What this trial is testingStudy BT8009-100 in Subjects With Nectin-4 Expressing Advanced MalignanciesWho this might be right forUrinary Bladder NeoplasmTriple Negative Breast NeoplasmsHormone Receptor Positive, HER2-negative Neoplasms+5 more BicycleTx Limited 329
Early research (Phase 1)UnknownNCT04460456What this trial is testingSBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid TumorsWho this might be right forHER2 Positive Solid Tumors Silverback Therapeutics 58
Early research (Phase 1)Study completedNCT02892123What this trial is testingTrial of ZW25 (Zanidatamab) in Patients With Advanced HER2-expressing CancersWho this might be right forHER2-expressing Cancers Jazz Pharmaceuticals 279
Testing effectiveness (Phase 2)Ended earlyNCT03505710What this trial is testingDS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung CancerWho this might be right forNon-Small Cell Lung Cancer Daiichi Sankyo 181
Testing effectiveness (Phase 2)Ended earlyNCT04278144What this trial is testingA First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid TumorsWho this might be right forHER2-positive Solid TumorsHER2-positive Breast CancerHER2-positive Colorectal Cancer+2 more Bolt Biotherapeutics, Inc. 175
Early research (Phase 1)Study completedNCT00003002What this trial is testingHER-2/Neu Vaccine Plus GM-CSF in Treating Patients With Stage III or Stage IV Breast, Ovarian, or Non-small Cell Lung CancerWho this might be right forBreast CancerLung CancerOvarian Cancer University of Washington 60
Early research (Phase 1)Study completedNCT04319757What this trial is testingACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid TumorsWho this might be right forLocally Advanced Solid TumorMetastatic CancerSolid Tumor+2 more Acepodia Biotech, Inc. 12
Testing effectiveness (Phase 2)Looking for participantsNCT06695845What this trial is testingZanidatamab in Patients With HER2-expressing TumorsWho this might be right forBreast CancerGastric CancerEsophageal Cancer+9 more Jazz Pharmaceuticals 200
Early research (Phase 1)Study completedNCT00228358What this trial is testingCyclophosphamide or Denileukin Diftitox Followed By Expanding a Patient's Own T Cells in the Laboratory in Treating Patients With HER-2/Neu Overexpressing Metastatic Breast Cancer, Ovarian Cancer, or Non-Small Cell Lung Cancer Previously Treated With HER-2/Neu VaccineWho this might be right forHER2-positive Breast CancerRecurrent Breast CancerRecurrent Non-small Cell Lung Cancer+6 more University of Washington 8