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Results for “HER2-mutant Non-Small Cell Lung Cancer”

16 trials

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Showing 16 of 16 results

Testing effectiveness (Phase 2)UnknownNCT05016544
What this trial is testing

Inetetamab in Combination With Pyrotinib in HER2 Mutant or Amplified Advanced Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Sun Yat-sen University 48
Early research (Phase 1)Active Not RecruitingNCT06714617
What this trial is testing

Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

Who this might be right for
Breast Cancer Stage IIIHER2-positive Metastatic Breast CancerUnresectable Breast Carcinoma+11 more
SystImmune Inc. 120
Testing effectiveness (Phase 2)Study completedNCT01827267
What this trial is testing

Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung Cancer

Who this might be right for
HER2-mutant Non-Small Cell Lung Cancer
Puma Biotechnology, Inc. 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT05246514
What this trial is testing

A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC

Who this might be right for
HER2-mutant Non-Small Cell Lung Cancer
AstraZeneca 72
Early research (Phase 1)Active Not RecruitingNCT05650879
What this trial is testing

ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer

Who this might be right for
HER2 Mutant Non-small Cell Lung CancerHER2-positive Metastatic Breast CancerHER2 Gene Mutation+1 more
Enliven Therapeutics 198
Not applicableLooking for participantsNCT06809764
What this trial is testing

Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERUN)

Who this might be right for
Non-small Cell Lung Cancer
Daiichi Sankyo 150
Testing effectiveness (Phase 2)Ended earlyNCT03066206
What this trial is testing

Poziotinib in EGFR Exon 20 Mutant Advanced NSCLC

Who this might be right for
EGFR Exon 20 MutationERBB2 Gene MutationRecurrent Lung Non-Small Cell Carcinoma+1 more
M.D. Anderson Cancer Center 93
Early research (Phase 1)Study completedNCT05926180
What this trial is testing

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients with EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Who this might be right for
Non-small Cell Lung Cancer
Dizal Pharmaceuticals 25
Testing effectiveness (Phase 2)Looking for participantsNCT06734182
What this trial is testing

Neoadjuvant Envafolimab Plus Disitamab Vedotin and Carboplatin in Resectable HER2-Mutant Non-Small-Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Guangdong Provincial People's Hospital 25
Large-scale testing (Phase 3)Looking for participantsNCT07178795
What this trial is testing

BL-M07D1 vs Pembrolizumab-platinum Chemotherapy in First-line Treatment of HER2-mutant Advanced or Metastatic Non-squamous NSCLC

Who this might be right for
Non-squamous Non-small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 440
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06250777
What this trial is testing

Efficacy and Safety of T-DXd in HER2-mutant Advanced Lung Cancer Patients With Asymptomatic Brain Metastases

Who this might be right for
Non Small Cell Lung Cancer
Yonsei University 27
Testing effectiveness (Phase 2)Looking for participantsNCT07192068
What this trial is testing

Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.

Who this might be right for
Non-Small Cell Lung CancerSarcomaHead &Amp; Neck Cancer+2 more
UNICANCER 105
Early research (Phase 1)Looking for participantsNCT06625775
What this trial is testing

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultMetastatic Breast CancerAdvanced Breast Cancer+8 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 392
Testing effectiveness (Phase 2)UnknownNCT04706949
What this trial is testing

Pyrotinib Combined With Pemetrexed Plus Carboplatin in the First-line Treatment

Who this might be right for
Lung Cancer, Non-small Cell
Fudan University 26
Not applicableUnknownNCT05411276
What this trial is testing

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

Who this might be right for
HER2 Mutant Non-small Cell Lung Cancer
Beijing Chest Hospital 15
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300