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Results for “HER2-negative Breast Cancer Brain Metastases”

36 trials

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Showing 20 of 36 results

Testing effectiveness (Phase 2)Looking for participantsNCT04923542
What this trial is testing

Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases

Who this might be right for
Brain MetastasesHR+ Metastatic Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT05323955
What this trial is testing

Secondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of Tucatinib

Who this might be right for
Brain MetastasesHuman Epidermal Growth Factor 2 Positive Carcinoma of BreastAdvanced Breast Cancer
Carey Anders, M.D. 48
Testing effectiveness (Phase 2)UnknownNCT04158947
What this trial is testing

HER2+ Breast Cancer Patients With Active Brain Metastases Treated With Afatinib & T-DM1 vs. T-DM1 Alone

Who this might be right for
HER2-positive Breast CancerBrain Metastases
xuexin he 130
Testing effectiveness (Phase 2)Looking for participantsNCT06418594
What this trial is testing

Adebrelimab Plus Apatinib and Etoposide for the Treatment of HER2-Negative Breast Cancer Brain Metastasis

Who this might be right for
HER2-negative Breast Cancer Brain Metastases
Beijing 302 Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07136428
What this trial is testing

Asciminib in HER2+ Breast Cancer Brain Metastases

Who this might be right for
HER2+ Metastatic Breast Cancer
Duke University 42
Large-scale testing (Phase 3)UnknownNCT03613181
What this trial is testing

ANG1005 in Leptomeningeal Disease From Breast Cancer

Who this might be right for
Leptomeningeal CarcinomatosisLeptomeningeal MetastasesBrain Metastases+1 more
Angiochem Inc 150
Not applicableActive Not RecruitingNCT03881605
What this trial is testing

MRI Screening Versus SYMptom-directed Surveillance for Brain Metastases Among Patients with Triple Negative or HER2+ MBC

Who this might be right for
Breast NeoplasmBrain MetastasesTriple Negative Breast Cancer+1 more
Sunnybrook Health Sciences Centre 50
Not applicableLooking for participantsNCT06247449
What this trial is testing

MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer

Who this might be right for
Breast Cancer
Sunnybrook Health Sciences Centre 100
Testing effectiveness (Phase 2)Looking for participantsNCT06176261
What this trial is testing

DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs

Who this might be right for
Breast CancerBreast Cancer FemaleMetastatic Triple-Negative Breast Carcinoma+4 more
Sarah Sammons, MD 58
Testing effectiveness (Phase 2)Looking for participantsNCT04965064
What this trial is testing

Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling

Who this might be right for
Breast Cancer
University of Rochester 22
Testing effectiveness (Phase 2)WithdrawnNCT03637868
What this trial is testing

Eribulin in Brain Metastases From HER2-negative Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Institut Paoli-Calmettes
Testing effectiveness (Phase 2)Ended earlyNCT01132664
What this trial is testing

Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer

Who this might be right for
Metastatic Breast CancerHER2+ Breast Cancer
Novartis Pharmaceuticals 72
Testing effectiveness (Phase 2)Looking for participantsNCT05872347
What this trial is testing

Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.

Who this might be right for
Breast Cancer Brain Metastases
Shanghai Pharmaceuticals Holding Co., Ltd 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07539753
What this trial is testing

Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases

Who this might be right for
Breast CancerBrain MetastasesHR+/HER2- Breast Cancer
Nanfang Hospital, Southern Medical University 46
Testing effectiveness (Phase 2)Study completedNCT02048059
What this trial is testing

ANG1005 in Breast Cancer Patients With Recurrent Brain Metastases

Who this might be right for
Breast CancerBrain Metastases
Angiochem Inc 72
Not applicableUnknownNCT03617341
What this trial is testing

Brain Monitoring for High Risk of Brain Metastases in Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer With HER2 PositiveTriple Negative Breast Cancer
Yonsei University 200
Testing effectiveness (Phase 2)Ended earlyNCT02774681
What this trial is testing

Palbociclib in Treating Patients With Metastatic HER-2 Positive Breast Cancer With Brain Metastasis

Who this might be right for
Breast Carcinoma Metastatic in the BrainEstrogen Receptor NegativeHER2/Neu Negative+4 more
Northwestern University 12
Early research (Phase 1)Study completedNCT01921335
What this trial is testing

ARRY-380 + Trastuzuamab for Breast w/ Brain Mets

Who this might be right for
Brain Metastases From HER2 and Breast CancerAdvanced HER2-positive Breast Cancer
Dana-Farber Cancer Institute 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT04647916
What this trial is testing

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast CarcinomaMetastatic HER2 Negative Breast Carcinoma+2 more
SWOG Cancer Research Network 44
Testing effectiveness (Phase 2)Looking for participantsNCT05386108
What this trial is testing

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Who this might be right for
Breast NeoplasmsBrain NeoplasmsNeoplasms by Site+5 more
Stemline Therapeutics, Inc. 73
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