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Results for “HER2-negative Breast Cancer Patients With Brain Metastases”

25 trials

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Showing 20 of 25 results

Testing effectiveness (Phase 2)Study completedNCT02048059
What this trial is testing

ANG1005 in Breast Cancer Patients With Recurrent Brain Metastases

Who this might be right for
Breast CancerBrain Metastases
Angiochem Inc 72
Testing effectiveness (Phase 2)Study completedNCT02260531
What this trial is testing

Cabozantinib +/- Trastuzumab In Breast Cancer Patients w/ Brain Metastases

Who this might be right for
Breast CancerBrain Tumor - Metastatic
Dana-Farber Cancer Institute 36
Post-approval studies (Phase 4)Looking for participantsNCT05376878
What this trial is testing

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT04647916
What this trial is testing

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Invasive Breast CarcinomaMetastatic HER2 Negative Breast Carcinoma+2 more
SWOG Cancer Research Network 44
Not applicableLooking for participantsNCT06247449
What this trial is testing

MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer

Who this might be right for
Breast Cancer
Sunnybrook Health Sciences Centre 100
Testing effectiveness (Phase 2)UnknownNCT04760431
What this trial is testing

TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN)

Who this might be right for
HER2-positive Breast CancerBrain Metastases
Second Affiliated Hospital, Zhejiang University, School of Medicine 120
Testing effectiveness (Phase 2)Ended earlyNCT04791384
What this trial is testing

Phase Ib/II Trial of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer

Who this might be right for
Breast Cancer
Criterium, Inc. 5
Large-scale testing (Phase 3)Looking for participantsNCT03418961
What this trial is testing

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Who this might be right for
CardiotoxicityHER2/Neu PositiveMetastatic Malignant Neoplasm in the Brain+2 more
SWOG Cancer Research Network 491
Testing effectiveness (Phase 2)Looking for participantsNCT06764940
What this trial is testing

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

Who this might be right for
HER2-negative Breast Cancer Patients With Brain Metastases
Biostar Pharma, Inc. 120
Testing effectiveness (Phase 2)UnknownNCT04158947
What this trial is testing

HER2+ Breast Cancer Patients With Active Brain Metastases Treated With Afatinib & T-DM1 vs. T-DM1 Alone

Who this might be right for
HER2-positive Breast CancerBrain Metastases
xuexin he 130
Testing effectiveness (Phase 2)Looking for participantsNCT05535413
What this trial is testing

UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases

Who this might be right for
Metastatic HER2 Negative Breast CarcinomaBrain MetastasesCapecitabine+1 more
Hunan Cancer Hospital 30
Testing effectiveness (Phase 2)Study completedNCT02614794
What this trial is testing

Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer

Who this might be right for
HER2 Positive Breast Cancer
Seagen Inc. 612
Early research (Phase 1)WithdrawnNCT06137651
What this trial is testing

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Who this might be right for
Breast CarcinomaMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges
Northwestern University
Large-scale testing (Phase 3)UnknownNCT03613181
What this trial is testing

ANG1005 in Leptomeningeal Disease From Breast Cancer

Who this might be right for
Leptomeningeal CarcinomatosisLeptomeningeal MetastasesBrain Metastases+1 more
Angiochem Inc 150
Testing effectiveness (Phase 2)Study completedNCT03328884
What this trial is testing

Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients

Who this might be right for
Breast Cancer Metastatic
MedSIR 55
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07539753
What this trial is testing

Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases

Who this might be right for
Breast CancerBrain MetastasesHR+/HER2- Breast Cancer
Nanfang Hospital, Southern Medical University 46
Not applicableActive Not RecruitingNCT03881605
What this trial is testing

MRI Screening Versus SYMptom-directed Surveillance for Brain Metastases Among Patients with Triple Negative or HER2+ MBC

Who this might be right for
Breast NeoplasmBrain MetastasesTriple Negative Breast Cancer+1 more
Sunnybrook Health Sciences Centre 50
Testing effectiveness (Phase 2)Looking for participantsNCT06839560
What this trial is testing

Evaluating the Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With VEX Metronomic Chemotherapy and Concurrent or Delayed Radiotherapy in Patients With Advanced HER2-Negative Breast Cancer With Brain Metastasis

Who this might be right for
Brain Metastasis From Advanced HER2-negative Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102
Testing effectiveness (Phase 2)Looking for participantsNCT05872347
What this trial is testing

Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.

Who this might be right for
Breast Cancer Brain Metastases
Shanghai Pharmaceuticals Holding Co., Ltd 52
Testing effectiveness (Phase 2)Ended earlyNCT01217411
What this trial is testing

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Who this might be right for
Adult Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaHER2/Neu Negative+10 more
National Cancer Institute (NCI) 5
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