Testing effectiveness (Phase 2)Study completedNCT00444535What this trial is testingLapatinib and Bevacizumab for Metastatic Breast CancerWho this might be right forNeoplasms, Breast Novartis Pharmaceuticals 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06439550What this trial is testingAdjuvant Treatment With Serplulimab，Trastuzumab and SOX in the HER-2 Positive GC/GEJCWho this might be right forHER2-positive Gastric Cancer The First Affiliated Hospital of Zhengzhou University 42
Not applicableStudy completedNCT05584644What this trial is testingDescribe the Breast Cancer Patient Population, Treatment, and Results in Indian Patients Receiving Combinations of the Medicines Called Palbociclib for Advanced Breast CancerWho this might be right forBreast CancerBreast CarcinomaBreast Neoplasms+2 more Pfizer 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT05323955What this trial is testingSecondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of TucatinibWho this might be right forBrain MetastasesHuman Epidermal Growth Factor 2 Positive Carcinoma of BreastAdvanced Breast Cancer Carey Anders, M.D. 48
Large-scale testing (Phase 3)Study completedNCT00390455What this trial is testingFulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-PositiveWho this might be right forEstrogen Receptor PositiveHER2 Positive Breast CarcinomaHER2/Neu Negative+5 more National Cancer Institute (NCI) 295
Testing effectiveness (Phase 2)UnknownNCT03185988What this trial is testingAnti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive SystemWho this might be right forTargeted TherapyHER2Biliary Tract Cancer+2 more Shen Lin 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04762979What this trial is testingAlpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast CancerWho this might be right forHormone Receptor Positive Breast CarcinomaHER2-negative Breast CancerPIK3CA Mutant Metastatic Breast Cancer Marina N Sharifi 44
Testing effectiveness (Phase 2)Study completedNCT01922921What this trial is testingVaccine Therapy With or Without Polysaccharide-K in Patients With Stage IV HER2 Positive Breast Cancer Receiving HER2-Targeted Monoclonal Antibody TherapyWho this might be right forHER2/Neu PositiveRecurrent Breast CarcinomaStage IV Breast Cancer University of Washington 31
Testing effectiveness (Phase 2)Study completedNCT03613168What this trial is testingTrastuzumab in HER2-positive Biliary Tract CancerWho this might be right forCholangiocarcinomaBiliary Tract CancerHER-2 Protein Overexpression+1 more Changhoon Yoo 4
Early research (Phase 1)Study completedNCT03455270What this trial is testingG1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast CancerWho this might be right forCarcinoma, Ductal, BreastBreast Cancer FemaleBreast Neoplasm+4 more G1 Therapeutics, Inc. 107
Testing effectiveness (Phase 2)Study completedNCT04505826What this trial is testingA Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast CancerWho this might be right forHormone Receptor Positive Breast CarcinomaHER2-negative Breast Cancer Olema Pharmaceuticals, Inc. 153
Testing effectiveness (Phase 2)Looking for participantsNCT06224673What this trial is testingARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast CancerWho this might be right forHER2 Low Breast CarcinomaTriple Negative Breast CancerHormone-receptor-positive Breast Cancer+1 more Laura Huppert, MD, BA 36
Not applicableLooking for participantsNCT07030569What this trial is testingRADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 StudyWho this might be right forRadiomicRadiomicsBreast Cancer Metastatic+13 more Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 500
Testing effectiveness (Phase 2)UnknownNCT02983071What this trial is testingG1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast CancerWho this might be right forCarcinoma, Ductal, BreastBreast CancerBreast Neoplasm G1 Therapeutics, Inc. 102
Testing effectiveness (Phase 2)Active Not RecruitingNCT02957968What this trial is testingNeoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast CaWho this might be right forBreast AdenocarcinomaEstrogen Receptor- Negative Breast CancerEstrogen Receptor-positive Breast Cancer+10 more Virginia Commonwealth University 46
Testing effectiveness (Phase 2)Ended earlyNCT01754519What this trial is testingRadiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing SurgeryWho this might be right forDuctal Breast Carcinoma In SituEstrogen Receptor NegativeEstrogen Receptor Positive+12 more Roswell Park Cancer Institute 1
Early research (Phase 1)Study completedNCT03854903What this trial is testingWI231696: Bosutinib, Palbocicilib and Fulvestrant for HR+HER2- Advanced Breast Cancer Refractory to a CDK4/6 InhibitorWho this might be right forMetastatic Breast CancerHuman Epidermal Growth Factor 2 Negative Carcinoma of BreastHormone Receptor Positive Breast Cancer Georgetown University 19
Testing effectiveness (Phase 2)UnknownNCT06519110What this trial is testingNeratinib Tablets Monotherapy for Advanced Solid Tumors With HER2 MutationsWho this might be right forAdvanced Solid Tumor Convalife (Shanghai) Co., Ltd. 60
Not applicableWithdrawnNCT07136493What this trial is testingCirculating Tumor DNA Based Minimal Residual Disease Detection for Patients With Early-Stage Breast CancerWho this might be right forAnatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+4 more City of Hope Medical Center
Testing effectiveness (Phase 2)WithdrawnNCT03326258What this trial is testingGlembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by SurgeryWho this might be right forAdvanced Malignant Solid NeoplasmEstrogen Receptor NegativeGPNMB Positive+15 more National Cancer Institute (NCI)