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Results for “HER2-positive Colorectal Cancer”

60 trials

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Showing 20 of 60 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT06589830
What this trial is testing

TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticAdvanced Colorectal Cancer
Suzhou Teligene Ltd. 80
Testing effectiveness (Phase 2)Looking for participantsNCT07407465
What this trial is testing

Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer.

Who this might be right for
Colorectal CancerColorectal AdenocarcinomaRectal Adenocarcinoma+4 more
Gruppo Oncologico del Nord-Ovest 42
Early research (Phase 1)Study completedNCT03251378
What this trial is testing

A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers

Who this might be right for
Advanced Solid TumorsMetastatic Colon CancerMetastatic Breast Cancer+4 more
Hutchison Medipharma Limited 129
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243938
What this trial is testing

Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET)

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Locally Advanced Gastric/Gastroesophageal Junction AdenocarcinomaMetastatic Colorectal Cancer (mCRC)+1 more
Tao Zhang 70
Testing effectiveness (Phase 2)WithdrawnNCT05356897
What this trial is testing

Tucatinib Combined with Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Rectal Adenocarcinoma+3 more
Academic and Community Cancer Research United
Testing effectiveness (Phase 2)UnknownNCT03225937
What this trial is testing

Evaluation of Trastuzumab in Combination With Lapatinib or Pertuzumab in Combination With Trastuzumab-Emtansine to Treat Patients With HER2-positive Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Fondazione del Piemonte per l'Oncologia 54
Not applicableEnded earlyNCT04106167
What this trial is testing

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Who this might be right for
Advanced Solid TumorLymphomaGastric Cancer+15 more
Fate Therapeutics 20
Early research (Phase 1)Looking for participantsNCT04704661
What this trial is testing

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Who this might be right for
Advanced Breast CarcinomaAdvanced Colon CarcinomaAdvanced Colorectal Carcinoma+37 more
National Cancer Institute (NCI) 51
Testing effectiveness (Phase 2)Temporarily pausedNCT05062889
What this trial is testing

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients

Who this might be right for
Stage II Colon CancerStage III Colon CancerHER2-positive Colon Cancer+1 more
Gruppo Oncologico del Nord-Ovest 477
Early research (Phase 1)UnknownNCT04460456
What this trial is testing

SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid Tumors

Who this might be right for
HER2 Positive Solid Tumors
Silverback Therapeutics 58
Early research (Phase 1)Looking for participantsNCT07318805
What this trial is testing

Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Breast CancerMetastatic Breast Cancer (HR+/ HER2-)Colorectal Cancer+2 more
Pfizer 260
Testing effectiveness (Phase 2)UnknownNCT03185988
What this trial is testing

Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System

Who this might be right for
Targeted TherapyHER2Biliary Tract Cancer+2 more
Shen Lin 100
Not applicableApproved For MarketingNCT04100694
What this trial is testing

Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Who this might be right for
NRG1 FusionPancreatic CancerNon Small Cell Lung Cancer+8 more
Merus B.V.
Early research (Phase 1)Study completedNCT01576666
What this trial is testing

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Who this might be right for
Dose EscalationSafetyPreliminary Efficacy+9 more
Novartis Pharmaceuticals 120
Testing effectiveness (Phase 2)Ended earlyNCT05091528
What this trial is testing

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Who this might be right for
HER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more
Silverback Therapeutics 2
Testing effectiveness (Phase 2)WithdrawnNCT04464967
What this trial is testing

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Who this might be right for
Advanced Solid TumorMetastatic CancerHER2-positive Breast Cancer+14 more
NKGen Biotech, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT04899908
What this trial is testing

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Who this might be right for
Brain CancerBrain MetastasesMelanoma+13 more
Brigham and Women's Hospital 134
Early research (Phase 1)Looking for participantsNCT06500052
What this trial is testing

BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors

Who this might be right for
Esophageal CancerGastric CancerPancreatic Cancer+2 more
Sichuan Baili Pharmaceutical Co., Ltd. 20
Early research (Phase 1)Active Not RecruitingNCT06328738
What this trial is testing

ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer

Who this might be right for
HER2-positive Breast CancerHER2-positive Gastric CancerHER2 Positive Solid Tumors+2 more
Enliven Therapeutics 275
Testing effectiveness (Phase 2)UnknownNCT03418558
What this trial is testing

Study of Trastuzumab-emtansine in Patients With HER2-positive Metastatic Colorectal Cancer Progressing After Trastuzumab and Lapatinib.

Who this might be right for
Metastatic Colorectal Cancer
Fondazione del Piemonte per l'Oncologia 13
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