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Results for “HER2-positive Early-stage Breast Cancer”

234 trials

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Showing 20 of 234 results

Large-scale testing (Phase 3)UnknownNCT01093235
What this trial is testing

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer

Who this might be right for
Breast CancerCardiac ToxicityPerioperative/Postoperative Complications
Cambridge University Hospitals NHS Foundation Trust 800
Testing effectiveness (Phase 2)Ended earlyNCT04066790
What this trial is testing

Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

Who this might be right for
Breast Cancer
Shanghai Jiao Tong University School of Medicine 12
Large-scale testing (Phase 3)Study completedNCT03726879
What this trial is testing

Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 454
Testing effectiveness (Phase 2)Study completedNCT01973660
What this trial is testing

PAM50 HER2-enriched Phenotype as a Predictor of Response to Dual HER2 Blockade in HER2-positive Early Breast Cancer

Who this might be right for
Breast Cancer
SOLTI Breast Cancer Research Group 151
Testing effectiveness (Phase 2)Study completedNCT05444998
What this trial is testing

Neoadjuvant Inetetamab and Pyrotinib and Nab-paclitaxel for HER2+Breast Cancer

Who this might be right for
Breast Cancer
Xijing Hospital 20
Large-scale testing (Phase 3)Ended earlyNCT04752332
What this trial is testing

Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer

Who this might be right for
Breast Neoplasms
Eli Lilly and Company 111
Large-scale testing (Phase 3)Not Yet RecruitingNCT07153757
What this trial is testing

De-escalation Therapy in Stage I ER-Positive Breast Cancer: A Non-Inferiority Trial

Who this might be right for
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Fudan University 2,934
Not applicableNot Yet RecruitingNCT07589972
What this trial is testing

Neoadjuvant Trastuzumab, Pertuzumab Plus Metronomic Vinorelbine for Elderly HER2-Positive Breast Cancer

Who this might be right for
Neoadjuvant Therapy in Elderly HER2-Positive Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 45
Large-scale testing (Phase 3)Looking for participantsNCT07057427
What this trial is testing

Efficacy of Nab-PHP Versus TCbHP in Neoadjuvant Therapy for HER2-positive Early Breast Cancer

Who this might be right for
Breast Cancer
Henan Cancer Hospital 812
Testing effectiveness (Phase 2)Ended earlyNCT01891357
What this trial is testing

Phase II Trial to Validate Markers for a Response Evaluation of a Combined Therapy in Patients With HER2+ Breast Cancer

Who this might be right for
Carcinoma, Ductal, Breast
Women's Cancer Study Group GmbH 64
Large-scale testing (Phase 3)Active Not RecruitingNCT07196774
What this trial is testing

A Trial of SHR-A1811 Compared to Other Antitumor Therapies as Neoadjuvant Treatments in Early-stage or Locally Advanced HER2-positive Breast Cancer

Who this might be right for
Early-stage or Locally Advanced HER2-positive Breast Cancer
Jiangsu HengRui Medicine Co., Ltd. 740
Testing effectiveness (Phase 2)UnknownNCT04881929
What this trial is testing

Study of KN026 in Combination With Docetaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

Who this might be right for
Breast Cancer
Jiangsu Alphamab Biopharmaceuticals Co., Ltd 30
Large-scale testing (Phase 3)Ended earlyNCT06038539
What this trial is testing

Efficacy and Safety of the Proposed Biosimilar Pertuzumab (PERT-IJS) Versus EU-Perjeta® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer

Who this might be right for
HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients
Biocon Biologics UK Ltd 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT05826964
What this trial is testing

Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer

Who this might be right for
Breast CancerER-positive Breast CancerHER2-negative Breast Cancer+1 more
University of Miami 24
Large-scale testing (Phase 3)Active Not RecruitingNCT02568839
What this trial is testing

Neoadjuvant Response-guided Treatment of HER2 Positive Breast Cancer

Who this might be right for
Early-Stage Breast CarcinomaHER-2 Positive Breast Cancer
Thomas Hatschek 202
Early research (Phase 1)Study completedNCT01576666
What this trial is testing

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Who this might be right for
Dose EscalationSafetyPreliminary Efficacy+9 more
Novartis Pharmaceuticals 120
Testing effectiveness (Phase 2)Looking for participantsNCT04481932
What this trial is testing

Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
Peking University 104
Testing effectiveness (Phase 2)Looking for participantsNCT06001086
What this trial is testing

A Phase II Clinical Study of Treatment With Disitamb Vedotin Plus Pyrotinib in HER2-positive Early Breast Cancer

Who this might be right for
Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 70
Testing effectiveness (Phase 2)Study completedNCT05549505
What this trial is testing

A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery

Who this might be right for
Breast Cancer
Arvinas Inc. 152
Not applicableLooking for participantsNCT06894173
What this trial is testing

EvoLution of Neoadjuvant TreatMent in 'Triple-negative' or 'HER-2-positive' Breast Cancer Diagnosed in the EaRly Phase

Who this might be right for
Breast Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 1,000
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