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Results for “HER2-positive Primary Malignancy”

69 trials

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Showing 20 of 69 results

Testing effectiveness (Phase 2)Study completedNCT02682693
What this trial is testing

Denosumab as an add-on Neoadjuvant Treatment (GeparX)

Who this might be right for
Breast Cancer Female NOSTubular Breast Cancer Stage IIMucinous Breast Cancer Stage II+4 more
GBG Forschungs GmbH 780
Testing effectiveness (Phase 2)Study completedNCT01432223
What this trial is testing

Primary Chemotherapy With Anthracycline Followed by Nab-paclitaxel and Trastuzumab

Who this might be right for
Breast CancerHER-2 Positive Breast CancerEffects of Chemotherapy
Osaka Medical College 46
Testing effectiveness (Phase 2)Ended earlyNCT01891357
What this trial is testing

Phase II Trial to Validate Markers for a Response Evaluation of a Combined Therapy in Patients With HER2+ Breast Cancer

Who this might be right for
Carcinoma, Ductal, Breast
Women's Cancer Study Group GmbH 64
Not applicableNot Yet RecruitingNCT07198672
What this trial is testing

Primary Prevention of Thrombocytopenia Associated With T-DM1 Therapy in HER2 Positive Breast Cancer With Herombopag

Who this might be right for
HER2-positive Breast Cancer
Zhenzhen Liu 45
Testing effectiveness (Phase 2)Study completedNCT02488564
What this trial is testing

Liposomal Doxorubicin+Docetaxel+Trastuzumab+Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer

Who this might be right for
HER-2 Positive Breast Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 49
Large-scale testing (Phase 3)Study completedNCT02422615
What this trial is testing

Study of Efficacy and Safety of LEE011 in Men and Postmenopausal Women With Advanced Breast Cancer.

Who this might be right for
Advanced Breast Cancer
Novartis Pharmaceuticals 726
Not applicableLooking for participantsNCT04660435
What this trial is testing

To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer

Who this might be right for
Metastatic Breast CancerER Positive Breast CancerHER2-negative Breast Cancer
Fondazione Sandro Pitigliani 150
Testing effectiveness (Phase 2)Ended earlyNCT01217411
What this trial is testing

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Who this might be right for
Adult Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaHER2/Neu Negative+10 more
National Cancer Institute (NCI) 5
Not applicableEnded earlyNCT05068726
What this trial is testing

Clinical Utility of FES F18 PET/CT in Metastatic Breast Cancer Patients

Who this might be right for
Metastatic Breast Cancer
GE Healthcare 51
Large-scale testing (Phase 3)Study completedNCT01358877
What this trial is testing

Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 4,804
Large-scale testing (Phase 3)Ended earlyNCT03050398
What this trial is testing

A Companion Sample Collection Protocol to Support the Discovery of Breast Cancer Aberrations With Treatment of CDK4/6 Therapy/LEE011/Ribociclib

Who this might be right for
Breast Cancer
Novartis Pharmaceuticals 8
Large-scale testing (Phase 3)Looking for participantsNCT03561740
What this trial is testing

The Addition of Metronomic Capecitabine to Standard Adjuvant Therapy in High Risk HER2+ BC paTients

Who this might be right for
Breast Cancer
Sun Yat-sen University 794
Testing effectiveness (Phase 2)Study completedNCT01816594
What this trial is testing

NeoPHOEBE: Neoadjuvant Trastuzumab + BKM120 in Combination With Weekly Paclitaxel in HER2-positive Primary Breast Cancer

Who this might be right for
HER2-positive Newly Diagnosed, Primary Breast Cancer
Novartis Pharmaceuticals 50
Large-scale testing (Phase 3)Study completedNCT01864746
What this trial is testing

Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery

Who this might be right for
Breast CancerHormonreceptor PositiveHer2-normal+2 more
GBG Forschungs GmbH 1,250
Large-scale testing (Phase 3)Active Not RecruitingNCT01805271
What this trial is testing

Safety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse, ER+ and HER2- Primary Breast Cancer, Free of Disease After Receiving at Least One Year of Adjuvant Hormone Therapy

Who this might be right for
Primary Non-metastatic Breast CancerWho Remain Disease-free
UNICANCER 1,278
Not applicableStudy completedNCT00898898
What this trial is testing

Studying Tissue Samples From Women With Breast Cancer Who Were Treated on Clinical Trial NCCTG-N9831

Who this might be right for
Breast Cancer
Alliance for Clinical Trials in Oncology 2,837
Large-scale testing (Phase 3)Study completedNCT04109066
What this trial is testing

Study of Nivolumab Versus Placebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy in Participants With High-risk, Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor 2-Negative (HER2-) Primary Breast Cancer

Who this might be right for
Breast Cancer
Bristol-Myers Squibb 521
Large-scale testing (Phase 3)Active Not RecruitingNCT04622319
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Who this might be right for
HER2-Positive Primary Breast CancerResidual Invasive Breast Cancer
Daiichi Sankyo 1,600
Testing effectiveness (Phase 2)Ended earlyNCT01185509
What this trial is testing

Trastuzumab and Vinorelbine in Advanced Breast Cancer

Who this might be right for
Breast CancerMetastatic Breast Cancer
Dana-Farber Cancer Institute 31
Testing effectiveness (Phase 2)Study completedNCT01172223
What this trial is testing

Primary Chemotherapy in Patients With HER2-positive Early Breast Cancer

Who this might be right for
Breast Cancer
Prof Dirk Elling 81
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