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Results for “HGPS”

22 trials

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Showing 20 of 22 results

Testing effectiveness (Phase 2)Study completedNCT00879034
What this trial is testing

Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

Who this might be right for
ProgeriaHutchinson-Gilford Syndrome
Boston Children's Hospital 5
Not applicableStudy completedNCT02876809
What this trial is testing

A Model for Healthy Aging: Moscow Centenarians (AGE-100)

Who this might be right for
Aging
Pirogov Russian National Research Medical University 100
Early research (Phase 1)Study completedNCT04512963
What this trial is testing

Phase I Study of Progerinin in Healthy Volunteers

Who this might be right for
Hutchinson-Gilford Progeria SyndromeWerner Syndrome
PRG Science & Technology Co., Ltd. 64
Not applicableStudy completedNCT01776125
What this trial is testing

Genetic Evaluation of NF1 and Scoliosis Patients

Who this might be right for
Neurofibromatosis 1Scoliosis
University of Minnesota 59
Not applicableNo Longer AvailableNCT05154851
What this trial is testing

HBCMD01- Expanded Access for the Treatment of Congenital Muscular Dystrophy.

Who this might be right for
Congenital Muscular Dystrophy Due to Lamin A/C Mutation
Hope Biosciences Research Foundation
Large-scale testing (Phase 3)Ended earlyNCT03439514
What this trial is testing

ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation

Who this might be right for
Dilated CardiomyopathyLamin A/C Gene Mutation
Pfizer 77
Testing effectiveness (Phase 2)Active Not RecruitingNCT06775041
What this trial is testing

Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)

Who this might be right for
Hutchinson-Gilford Progeria Syndrome
PRG Science & Technology Co., Ltd. 10
Not applicableLooking for participantsNCT06628895
What this trial is testing

Effect of Modified Poco-Poco Exercise to Frailty Stages, Expression of Global DNA Methylation, GDF15 and Lamin A COP

Who this might be right for
Frail Elderly
Universitas Padjadjaran 17
Not applicableApproved For MarketingNCT03895528
What this trial is testing

Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome or Progeroid Laminopathy

Who this might be right for
ProgeriaHGPS
Eiger BioPharmaceuticals
Not applicableUnknownNCT03860454
What this trial is testing

The Deep Phenotype of Lamin A/C Cardiomyopathy

Who this might be right for
Lamin A/C Gene MutationDilated Cardiomyopathy, Familial
University College, London 150
Testing effectiveness (Phase 2)Study completedNCT02351856
What this trial is testing

A Rollover Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy

Who this might be right for
LMNA-Related Dilated Cardiomyopathy
Pfizer 8
Not applicableStudy completedNCT06936098
What this trial is testing

Deep Learning-Based Analysis of Colorectal Cancer Pathology Images: An Innovative Approach for Predicting Colorectal Cancer Subtypes

Who this might be right for
Colorectal Liver Metastasis (CRLM)Histopathological Growth Patterns (HGPs)Artificial Intelligence (AI) in Diagnosis+2 more
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 431
Not applicableStudy completedNCT00094393
What this trial is testing

Clinical Studies of Progeria

Who this might be right for
Progeria
National Human Genome Research Institute (NHGRI) 15
Not applicableLooking for participantsNCT03059420
What this trial is testing

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Who this might be right for
Congenital Fibrosis of Extraocular MusclesDuane Retraction SyndromeDuane Radial Ray Syndrome+23 more
Boston Children's Hospital 20,000
Testing effectiveness (Phase 2)Study completedNCT03871972
What this trial is testing

Umbilical Cord Blood Transfusion in Progeria Syndrome

Who this might be right for
Hutchinson-Gilford Progeria Syndrome
Bundang CHA Hospital 2
Not applicableLooking for participantsNCT03058185
What this trial is testing

Observatoire Des Patients Atteints de Laminopathies et Emerinopathies (Observatory for PAtients With Laminopathies and Emerinopathies)

Who this might be right for
LaminopathiesEmerinopathies
Pitié-Salpêtrière Hospital 800
Not applicableUnknownNCT04904393
What this trial is testing

Subanalysis in Patients With CARDIoLAMinopathy Enrolled to REPORT-CCM Registry

Who this might be right for
LaminopathyLamin A/C Gene MutationHeart Failure
Monaldi Hospital 20
Not applicableStudy completedNCT04646980
What this trial is testing

Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses

Who this might be right for
Influenza-like Illness
Zagazig University 80
Testing effectiveness (Phase 2)Study completedNCT00731016
What this trial is testing

Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledronic Acid

Who this might be right for
Hutchinson-Gilford Progeria Syndrome
Assistance Publique Hopitaux De Marseille 15
Testing effectiveness (Phase 2)Study completedNCT00425607
What this trial is testing

Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria

Who this might be right for
ProgeriaHutchinson-Gilford Syndrome
Monica E. Kleinman 29
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