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Results for “HIGM-1”

33 trials

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Showing 20 of 33 results

Early research (Phase 1)Study completedNCT00078520
What this trial is testing

Treatment of B-CLL With Human IL-2 and CD40 Ligand and Plasmid Gene Modified Autologous Tumor Cells

Who this might be right for
LeukemiaLeukemia, B-Cell, Chronic
Baylor College of Medicine 9
Early research (Phase 1)Study completedNCT00058786
What this trial is testing

Treatment of Chronic Lymphocytic B-Leukemia With IL-2 and CD-40 Autologous Tumor Cells

Who this might be right for
Chronic Lymphocytic B-Leukemia
Baylor College of Medicine 9
Not applicableStudy completedNCT04080453
What this trial is testing

Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock.

Who this might be right for
Septic Shock
University Hospital, Bordeaux 202
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Not applicableUnknownNCT00004341
What this trial is testing

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Who this might be right for
X-Linked AgammaglobulinemiaX-Linked Hyper IgM SyndromeWiskott-Aldrich Syndrome+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
Testing effectiveness (Phase 2)Study completedNCT01998633
What this trial is testing

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Who this might be right for
Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus InfectionChronic Granulomatous Disease+3 more
Medical College of Wisconsin 47
Large-scale testing (Phase 3)Study completedNCT01963143
What this trial is testing

Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinaemia+1 more
Bio Products Laboratory 48
Not applicableStudy completedNCT05059431
What this trial is testing

The Effect of Human Prostate Tissue on Platelet Activation

Who this might be right for
Prostate HyperplasiaCoagulation; IntravascularThrombotic Disorder
Tri-Service General Hospital (TSGH) 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT06305286
What this trial is testing

Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

Who this might be right for
Type 1 Diabetes Mellitus
University of Chicago 70
Testing effectiveness (Phase 2)Study completedNCT00730314
What this trial is testing

Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells

Who this might be right for
Sickle Cell DiseaseThalassemiaAnemia+9 more
Children's Hospital Los Angeles 25
Post-approval studies (Phase 4)Study completedNCT01289847
What this trial is testing

Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinemia+2 more
Bio Products Laboratory 25
Not applicableUnknownNCT00006319
What this trial is testing

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Who this might be right for
Wiskott- Aldrich SyndromeADA Deficient SCID
National Human Genome Research Institute (NHGRI) 266
Testing effectiveness (Phase 2)Study completedNCT00053391
What this trial is testing

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Melanoma (Skin)
University Hospital Erlangen 62
Early research (Phase 1)Study completedNCT00458679
What this trial is testing

Treatment of B-Chronic Lymphocytic Leukemia (B-CLL) With Autologous CD40 Ligand and IL-2-Expressing Tumor Cells

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)
Baylor College of Medicine 6
Not applicableActive Not RecruitingNCT01652092
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Who this might be right for
SCIDOmenn's SyndromeReticular Dysgenesis+11 more
Masonic Cancer Center, University of Minnesota 57
Testing effectiveness (Phase 2)WithdrawnNCT00504322
What this trial is testing

Efficacy Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma

Who this might be right for
Esophageal Neoplasms
Weill Medical College of Cornell University
Testing effectiveness (Phase 2)Ended earlyNCT03333486
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more
Roswell Park Cancer Institute 31
Not applicableLooking for participantsNCT06092346
What this trial is testing

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Who this might be right for
AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more
National Human Genome Research Institute (NHGRI)
Not applicableUnknownNCT00008749
What this trial is testing

Role of Altered CD40-Ligand Gene Transcription in Systemic Lupus Erythematosus

Who this might be right for
Lupus Erythematosus, Systemic
National Center for Research Resources (NCRR)
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