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Results for “HIGM-1”

33 trials

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Showing 20 of 33 results

Large-scale testing (Phase 3)Study completedNCT01963143
What this trial is testing

Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinaemia+1 more
Bio Products Laboratory 48
Testing effectiveness (Phase 2)WithdrawnNCT00504322
What this trial is testing

Efficacy Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma

Who this might be right for
Esophageal Neoplasms
Weill Medical College of Cornell University
Not applicableStudy completedNCT05059431
What this trial is testing

The Effect of Human Prostate Tissue on Platelet Activation

Who this might be right for
Prostate HyperplasiaCoagulation; IntravascularThrombotic Disorder
Tri-Service General Hospital 8
Testing effectiveness (Phase 2)Study completedNCT00001145
What this trial is testing

Study of Immune Responses and Safety of Recombinant Human CD40 Ligand in Patients With X-Linked Hyper-IgM Syndrome

Who this might be right for
Immunoproliferative Disorder
National Institute of Allergy and Infectious Diseases (NIAID) 5
Not applicableUnknownNCT00006319
What this trial is testing

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Who this might be right for
Wiskott- Aldrich SyndromeADA Deficient SCID
National Human Genome Research Institute (NHGRI) 266
Early research (Phase 1)Study completedNCT00058799
What this trial is testing

Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine

Who this might be right for
Leukemia
Baylor College of Medicine 11
Large-scale testing (Phase 3)Study completedNCT01884311
What this trial is testing

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinaemia+1 more
Bio Products Laboratory 38
Testing effectiveness (Phase 2)Ended earlyNCT00006113
What this trial is testing

Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Melanoma (Skin)
University of Southern California 25
Testing effectiveness (Phase 2)Study completedNCT01998633
What this trial is testing

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Who this might be right for
Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus InfectionChronic Granulomatous Disease+3 more
Medical College of Wisconsin 47
Testing effectiveness (Phase 2)Study completedNCT00730314
What this trial is testing

Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells

Who this might be right for
Sickle Cell DiseaseThalassemiaAnemia+9 more
Children's Hospital Los Angeles 25
Testing effectiveness (Phase 2)Study completedNCT00053391
What this trial is testing

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Melanoma (Skin)
University Hospital Erlangen 62
Not applicableUnknownNCT00004341
What this trial is testing

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Who this might be right for
X-Linked AgammaglobulinemiaX-Linked Hyper IgM SyndromeWiskott-Aldrich Syndrome+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Not applicableLooking for participantsNCT06092346
What this trial is testing

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Who this might be right for
AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more
National Human Genome Research Institute (NHGRI)
Not applicableUnknownNCT00008749
What this trial is testing

Role of Altered CD40-Ligand Gene Transcription in Systemic Lupus Erythematosus

Who this might be right for
Lupus Erythematosus, Systemic
National Center for Research Resources (NCRR)
Early research (Phase 1)WithdrawnNCT00224354
What this trial is testing

Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells

Who this might be right for
CHRONIC LYMPHOCYTIC B-LEUKEMIA
Baylor College of Medicine
Post-approval studies (Phase 4)Study completedNCT01289847
What this trial is testing

Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinemia+2 more
Bio Products Laboratory 25
Not applicableEnded earlyNCT00266513
What this trial is testing

Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States

Who this might be right for
Hyper-IgM SyndromeEctodermal Dysplasia
National Institute of Allergy and Infectious Diseases (NIAID) 119
Early research (Phase 1)Study completedNCT00078520
What this trial is testing

Treatment of B-CLL With Human IL-2 and CD40 Ligand and Plasmid Gene Modified Autologous Tumor Cells

Who this might be right for
LeukemiaLeukemia, B-Cell, Chronic
Baylor College of Medicine 9
Early research (Phase 1)Study completedNCT00058786
What this trial is testing

Treatment of Chronic Lymphocytic B-Leukemia With IL-2 and CD-40 Autologous Tumor Cells

Who this might be right for
Chronic Lymphocytic B-Leukemia
Baylor College of Medicine 9
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